Results 71 to 80 of about 2,948 (168)

Experimental substantiation of an opportunity of the use of vardenafil for pharmacological preconditioning in surgery

open access: yesКубанский научный медицинский вестник, 2015
The possibility of vardenafil using for pharmacological preconditioning in surgery is studied. Experiment was carried out on Wistar rats. The influence of vardenafil on the survival of pedicled isolated skin flap and the state of the microvasculature in ...
I. M. Kolesnik   +2 more
doaj  

Optimization of the Factors Affecting the Absorption of Vardenafil from Oral Disintegrating Tablets: A Clinical Pharmacokinetic Investigation

open access: yesPharmaceutics, 2019
Because of poor solubility and considerable metabolism, vardenafil (VRD) bioavailability is 15%. To overcome this obstacle, this study aimed to increase the solubility, hasten the onset of action, and mask the unpleasant taste of VRD utilizing &beta ...
Hytham A. Al-Gethmy   +4 more
doaj   +1 more source

Classical activation of macrophages and vardenafil [PDF]

open access: yesClinical Science, 2017
Inhibitors of phosphodiesterase 5 (PDE5) – sildenafil citrate (Viagra; Pfizer) and vardenafil hydrochloride (Levitra; Bayer/GlaxoSmithKline) – approved for the treatment of erectile dysfunction and pulmonary arterial hypertension also rescue the loss of cystic fibrosis (CF) chloride channel function and the mislocalization of F508del-CFTR in affected ...
openaire   +3 more sources

Evolution of phosphodiesterase type 5 inhibitors in treatment of erectile dysfunction in Taiwan

open access: yesUrological Science, 2016
Erectile dysfunction (ED) is a prevalent form of male sexual dysfunction. Phosphodiesterase type 5 (PDE5) inhibitor is the first-line treatment for ED. Numerous well-designed and -conducted clinical trials and postmarketing studies have established the ...
Bang-Ping Jiann
doaj   +1 more source

Vardenafil for the treatment of erectile dysfunction: an overview of the clinical evidence

open access: yesClinical Interventions in Aging, 2009
Antonio Martín Morales1, Vincenzo Mirone2, John Dean3, Pierre Costa41Department of Urology, Hospital Carlos Haya, Malaga, Spain; 2Department of Urology, University Federico II, Naples, Italy; 3St.
Antonio Martín Morales   +3 more
doaj  

Influence of regular use of vardenafil on endothelial and erectile functions in patients with arteriogenic erectile dysfunction

open access: yesТерапевтический архив, 2009
Aim. To study the influence of long-term of vardenafil use on endothelial and erectile functions in patients with arteriogenic erectile dysfunction (ED) Subjects and methods. The study included 74 arteriogenic ED patients (mean age 57.4 ± 4.7 years).
Safar Israilovich Gamidov   +7 more
doaj  

Erectile dysfunction drugs and oxidative stress in the liver of male rats

open access: yesToxicology Reports, 2015
Erectile dysfunction (ED) affected the lives of more than 300 million men worldwide. Erectile dysfunction drugs (EDD), known as phosphodiesterase inhibitors (PDEIs), have been used for treatment of ED.
Salah Sheweita   +2 more
doaj   +1 more source

A Bayesian network meta-analysis on the efficacy and safety of eighteen targeted drugs or drug combinations for pulmonary arterial hypertension

open access: yesDrug Delivery, 2018
Pulmonary arterial hypertension (PAH) can be relieved by pharmacological interventions, especially the targeted drug, which is classified into endothelin receptor antagonist, phosphodiesterase 5 inhibitor, prostaglandin I2, soluble guanylate cyclase ...
Sumei Wang   +3 more
doaj   +1 more source

Patient Insight and Treatment Expectations in Erectile Dysfunction [PDF]

open access: yesEuropean Medical Journal, 2016
In the literature, a strong preference towards pharmacological management with oral phosphodiesterase type 5 (PDE5) inhibitors has been demonstrated in men with erectile dysfunction (ED) versus other methods. However, following pharmacological management,
Hartmut Porst
doaj  

Sildenafil or Vardenafil Nonresponders’ Erectile Response to Tadalafil

open access: yesUrology Journal, 2009
Introduction: Erectile dysfunction has usually been treated by a phosphodiesterase 5 inhibitor in men, especially in the past decade. Although sildenafil and vardenafil are widely used, there is a high percentage of people who do not respond to these ...
Berat Cem Ozgur   +2 more
doaj  

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