Snakebite: An Exploratory Cost-Effectiveness Analysis of Adjunct Treatment Strategies. [PDF]
, 2018 The cost-effectiveness of the standard of care for snakebite treatment, antivenom, and supportive care has been established in various settings. In this study, based on data from South Indian private health-care providers, we address an additional ...
Bulfone, Tommaso C +5 more
core +2 more sources
Clinical management of snakebite envenoming: Future perspectives
Toxicon: X, 2021 Snakebite envenoming is a major cause of morbidity and mortality in rural communities throughout the tropics. Generally, the main clinical features of snakebites are local swelling, tissue necrosis, shock, spontaneous systemic hemorrhage, incoagulable ...
Muhammad Hamza +6 more
doaj
Validity and reliability of telephone administration of the patient-specific functional scale for the assessment of recovery from snakebite envenomation [PDF]
, 2019 OBJECTIVES: Although more than 1.8 million people survive snakebite envenomation each year, their recovery is understudied. Obtaining long-term follow-up is challenging in both high- and low-resource settings. The Patient-Specific Functional Scale (PSFS)
et al., +2 more
core +1 more source
Novel strategies to treat snake venom induced muscle damage [PDF]
Snakebite envenoming is a propriety neglected tropical disease that annually claims a life of around 150,000 and is responsible for 500,000 disabilities. Skeletal muscle damage is a primary factor for snake venom-induced permanent disabilities.
Sonavane, Medha
core +1 more source
The genetic architecture of Secretory PLA2 (sPLA2)genes and their impact on sPLA2 activity/mass and association with CHD risk. [PDF]
, 2012 Secretory phospholipase A2 group (sPLA2) enzymes hydrolyze the sn-2 ester bond of phospholipids, producing lysophospholipids and free fatty acids. SPLA2s have been identified as biomarkers of atherosclerosis in observational and animal studies.
Exeter, HJ
core
ASSESSING TARGET SPECIFICITY OF THE SMALL MOLECULE INHIBITOR MARIMASTAT TO SNAKE VENOM TOXINS: A NOVEL APPLICATION OF THERMAL PROTEOME PROFILING [PDF]
New treatments that circumvent the pitfalls of traditional antivenom therapies are critical to address the problem of snakebite globally. Numerous snake venom toxin inhibitors have shown promising cross-species neutralization of medically significant ...
Bahrabadi, Lilyrose +15 more
core +2 more sources
The Evolving Pharmacotherapeutic Landscape for the Treatment of Sickle Cell Disease. [PDF]
, 2020 Sickle cell disease (SCD) is an extremely heterogeneous disease that has been associated with global morbidity and early mortality. More effective and inexpensive therapies are needed.
Ballas, Samir K
core +1 more source
Limits of Mendelian Randomization Analyses in Selection of Secretory Phospholipase A2-IIA as a Valid Therapeutic Target for Prevention of Cardiovascular Disease [PDF]
, 2014 Hurt-Camejo, Eva, Rosenson, Robert S.
core +1 more source
Analytics for assessing the efficacy of snakebite treatment at neutralizing venom toxins [PDF]
, 2021 Xie, Chunfang
core
The Need for Next-Generation Antivenom for Snakebite Envenomation in India. [PDF]
Toxins (Basel), 2023 Vanuopadath M +4 more
europepmc +1 more source