Results 71 to 80 of about 44,318 (258)

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Variable-Parameter Impedance Control of Manipulator Based on RBFNN and Gradient Descent

Sensors
During the interaction process of a manipulator executing a grasping task, to ensure no damage to the object, accurate force and position control of the manipulator’s end-effector must be concurrently implemented. To address the computationally intensive
Linshen Li, Fan Wang, Huilin Tang, Yanbing Liang   +3 more
doaj   +1 more source

Hammerstein Adaptive Impedance Controller for Bionic Wrist Joint Actuated by Pneumatic Muscles

IEEE Access, 2019
For the nonlinear, time-variable and unpredictable environment (such as the manipulator workspace that has many random and moveable obstacles), a Hammerstein adaptive (HA) impedance controller based on a Hammerstein impedance model is proposed in this ...
Hui Yang, Xifeng Gao, Yang Chen, Lina Hao   +3 more
doaj   +1 more source

Data-Driven Variable Impedance Control of a Powered Knee-Ankle Prosthesis for Adaptive Speed and Incline Walking. [PDF]

IEEE Trans Robot, 2023
Best TK, Welker CG, Rouse EJ, Gregg RD.
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Design and Application of MVIC for Hydraulic Drive Unit of Legged Robot

IEEE Access, 2019
A hydraulic drive unit (HDU), applied in each joint of a hydraulic driven legged robot, usually adopts the impedance control outer loop based on the hydraulic position or the force control inner loop during the motion process.
Bin Yu, Kaixian Ba, Yaliang Liu, Zhengguo Jin, Qixin Zhu, Zhengjie Gao, Guoliang Ma, Xiangdong Kong   +7 more
doaj   +1 more source

Data-Driven Variable Impedance Control of a Powered Knee-Ankle Prosthesis for Sit, Stand, and Walk with Minimal Tuning. [PDF]

Rep U S, 2022
Welker CG, Best TK, Gregg RD.
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Impedance Learning-Based Hybrid Adaptive Control of Upper Limb Rehabilitation Robots

Actuators
This paper presents a hybrid adaptive control strategy for upper limb rehabilitation robots using impedance learning. The hybrid adaptation consists of a differential updating mechanism for the estimation of robotic modeling uncertainties and periodic ...
Zhenhua Jiang, Zekai Wang, Qipeng Lv, Jiantao Yang   +3 more
doaj   +1 more source