Results 91 to 100 of about 45,923 (289)

Hammerstein Adaptive Impedance Controller for Bionic Wrist Joint Actuated by Pneumatic Muscles

open access: yesIEEE Access, 2019
For the nonlinear, time-variable and unpredictable environment (such as the manipulator workspace that has many random and moveable obstacles), a Hammerstein adaptive (HA) impedance controller based on a Hammerstein impedance model is proposed in this ...
Hui Yang   +3 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Design and Application of MVIC for Hydraulic Drive Unit of Legged Robot

open access: yesIEEE Access, 2019
A hydraulic drive unit (HDU), applied in each joint of a hydraulic driven legged robot, usually adopts the impedance control outer loop based on the hydraulic position or the force control inner loop during the motion process.
Bin Yu   +7 more
doaj   +1 more source

Passive Variable Impedance For Shared Control

open access: yes
submitted for publication at the IEEE Robotics and Automation Letters (RA-L)
Mühlbauer, Maximilian   +6 more
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Micro-impedance cytometry

open access: yes, 2010
Electrical impedance spectroscopy is a non-invasive and label free technique that allows for rapid counting and characterisation of particles in suspension based on their response to applied AC potentials. In recent years, lab-on-a-chip technologies have
Bernabini, Catia
core  

Impedance Learning-Based Hybrid Adaptive Control of Upper Limb Rehabilitation Robots

open access: yesActuators
This paper presents a hybrid adaptive control strategy for upper limb rehabilitation robots using impedance learning. The hybrid adaptation consists of a differential updating mechanism for the estimation of robotic modeling uncertainties and periodic ...
Zhenhua Jiang   +3 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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