Results 81 to 90 of about 44,318 (258)

Passive Variable Impedance For Shared Control

open access: yes
submitted for publication at the IEEE Robotics and Automation Letters (RA-L)
Mühlbauer, Maximilian   +6 more
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

An Advanced Adaptive Control of Lower Limb Rehabilitation Robot

open access: yesFrontiers in Robotics and AI, 2018
Rehabilitation robots play an important role in the rehabilitation field, and effective human-robot interaction contributes to promoting the development of the rehabilitation robots. Though many studies about the human-robot interaction have been carried
Yihao Du   +5 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Fuzzy adaptive variable impedance control on deformable shield of defecation smart care robot

open access: yesBiomimetic Intelligence and Robotics
Precise control of the contact force is crucial in the application of non-wearable defecation smart care (DSC) robot. A deformable shield equipped with a pressure sensing function is designed, with a bending angle that can be adjusted according to ...
Lingling Chen   +3 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

A Comparative Case Study of EMG-Driven Controllers in Transtibial Prostheses

open access: yesIEEE Transactions on Neural Systems and Rehabilitation Engineering
Lower limb amputation greatly affects quality of life by restricting functional mobility. Despite advancements in prosthetic design, powered transtibial prostheses still have limitations in user control and adaptability to dynamic environments.
M. Abdelbar   +5 more
doaj   +1 more source

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