Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz +3 more
wiley +1 more source
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
A Multi-Neighborhood Multi-Operator Algorithm for the Uncapacitated Exam Proximity Problem [PDF]
An algorithm featuring multiple local search operators and multiple neighborhood structures is applied to the uncapacitated exam proximity problem. The use of multiplicity is to enable effective interplay between intensification and diversification ...
Tony Wong, Salah Assal
doaj
Novel variable neighborhood search heuristics for truck management in distribution warehouses problem. [PDF]
Sarhan AY +5 more
europepmc +1 more source
ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick +14 more
wiley +1 more source
Multi-objective home health care routing: a variable neighborhood search method. [PDF]
Kordi G, Divsalar A, Emami S.
europepmc +1 more source
Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle +11 more
wiley +1 more source
Critical-Path-Based Variable Neighborhood Descent for the Joint Scheduling of FJSP and AGVs
This study addresses the joint scheduling problem of flexible job shop scheduling and automated guided vehicles with the objective of minimizing the makespan.
Han Jia +4 more
doaj +1 more source
This paper considers the problem of scheduling a set of jobs on unrelated parallel machines subject to several constraints which are non-zero arbitrary release dates, limited additional resources, and non-anticipatory sequence-dependent setup times.
Ibrahim M. Al-harkan, Ammar A. Qamhan
doaj +1 more source
Variable Neighborhood Search for Multi-Cycle Medical Waste Recycling Vehicle Routing Problem with Time Windows. [PDF]
Zhang W, Zeng M, Guo P, Wen K.
europepmc +1 more source

