Results 81 to 90 of about 2,071 (159)

The genes for variant antigens in trypanosomes.

, 1980
We have studied the mechanism of antigenic variation by using DNA complementary to the messenger RNAs for four variant surface glycoproteins of Trypanosoma brucei.
Hoeijmakers, J.H.J. (Jan), Frasch, A.C.C., Borst, P. (Piet), Bernards, A. (André), G. A. M. Cross, A. C. C. Frasch, Ploeg, L.H.T. van der, P. Borst, A. Bernards, J. H. J. Hoeijmakers, Cross, G.A.M., L. H. T. van der Ploeg   +11 more
core   +1 more source

Carbohydrate-binding agents act as potent trypanocidals that elicit modifications in VSG glycosylation and reduced virulence in Trypanosoma brucei

, 2013
The surface of Trypanosoma brucei is covered by a dense coat of glycosylphosphatidylinositol-anchored glycoproteins. The major component is the variant surface glycoprotein (VSG) which is glycosylated by both paucimannose and oligomannose N-glycans ...
Igarashi, Yasuhiro, Castillo-Acosta, Víctor M., Ruiz-Pérez, Luis M., Van Damme, Els J. M., Vidal, Antonio E., Van Damme, Els J.M., Vidal, Antonio E, Ruiz-Pérez, Luis M, Van Damme, Els, Ruiz-Pérez, Luis Miguel, Castillo-Acosta, Victor M, González-Pacanowska, Dolores, Balzarini, Jan   +12 more
core   +1 more source

The glycosylation of the variant surface glycoproteins and procyclic acidic repetitive proteins of Trypanosoma brucei

, 1998
Trypanosoma brucei, in common with the other African trypanosomes, exhibits unusual cell-surface molecular architecture, The bloodstream form of the parasite is coated with a continuous layer of approximately five million variant surface glycoprotein ...
Richardson, Julia M., Ferguson, Michael A.J., Treumann, Achim, Mehlert, Angela, Zitzmann, Nicole, Ferguson, Michael A. J. ; id_orcid   +5 more
core   +1 more source

Protein structure controls the processing of the N-linked oligosaccharides and glycosylphosphatidylinositol glycans of variant surface glycoproteins expressed in bloodstream form Trypanosoma brucei

, 2000
The variant surface glycoproteins (VSGs) of Trypanosoma brucei are a family of homodimeric glycoproteins that adopt similar shapes. An individual trypanosome expresses one VSG at a time in the form of a dense protective mono­layer on the plasma membrane.
Ferguson, Michael A.J., Carroue, S, Rudd, Pauline M., Mehlert, A, Rudd, PM, Ferguson, Michael A. J.; id_orcid, Ferguson, MAJ, Zitzmann, N, Carrouée, S, Carroué, Sandra, Zitzmann, Nicole, Mehlert, Angela, Carrouée, Sandra   +12 more
core   +1 more source

The glycoforms of a Trypanosoma brucei variant surface glycoprotein and molecular modeling of a glycosylated surface coat

, 2002
The plasma membrane of the African sleeping sickness parasite Trypanosoma brucei is covered with a dense, protective surface coat. This surface coat is a monolayer of five million variant surface glycoprotein (VSG) dimers that form a macromolecular ...
C. S. Bond, A. Mehlert, M. A.J. Ferguson, Bond, Charles S., Mehlert, Angela, Ferguson, Michael A. J. ; id_orcid   +5 more
core   +1 more source

The membrane-anchoring systems of vertebrate acetylcholinesterase and variant surface glycoproteins of African trypanosomes share a common antigenic determinant

, 1986
Amphiphilic detergent-soluble acetylcholinesterase (AChE) from Torpedo is converted to a hydrophilic form by digestion with phospholipase C from Trypanosoma brucei or from Bacillus cereus. This lipase digestion uncovers an immunological determinant which
A. Stieger, Stieger, A., Brodbeck, U., C. Bordier, Bordier, C., M.-L.Cardoso de Almeida, U. Brodbeck, de Almeida, M.-L.Cardoso, Blatter, M.-C., M.-C. Blatter   +9 more
core   +1 more source

Candidate glycophospholipid precursor for the glycosylphosphatidylinositol membrane anchor of Trypanosoma brucei variant surface glycoproteins

, 1988
Trypanosoma brucei variant surface glycoproteins are apparently synthesized with a hydrophobic carboxyl-terminal peptide that is cleaved and replaced by a complex glycosylphosphatidylinositol membrane anchor within 1 min of the completion of the ...
Duszenko, Michael, Cross, George A. M., Ferguson, Michael A. J.; id_orcid, Menon, Anant K., Mayor, Satyajit   +4 more
core  

Epidemiology, control and potential insect vectors of Trypanosoma evansi (surra) in village livestock in southern Philippines

, 2010
The objective of this project was to determine the extent and impact of infection with Trypanosoma evansi in livestock in Mindanao, Philippines, evaluate economic benefits of control options and determine its vectors.
Dargantes, Alan
core  

The primary structure of Trypanosoma (Nannomonas) congolense variant surface glycoproteins

, 2013
The complete nucleotide sequences were determined for three transcripts each encoding a different variant surface glycoprotein (VSG) of Trypanosoma (Nannomonas) congolense.
Urakawa, T., Eshita, Y., Majiwa, Phelix A.O.   +2 more
core  

Glucose induces lipolytic cleavage of a glycolipidic plasma membrane anchor in yeast [PDF]

, 1993
W Bandlow, G Müller, Bandlow, Wolfhard, Müller, Günter   +3 more
core   +1 more source