Results 111 to 120 of about 1,835,894 (312)

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

HD-and-RNA-variants-Chr17.vcf

, 2017
All HD and RNAseq variants on chromosome 17.
Thomas Lopdell (511314), Russell Snell (387740), Davis, Steve, Christine Couldrey (169434), Maksim Struchalin (166855), Steve Davis (5017841), Kathryn Tiplady (511313), Littlejohn, Mathew, Couldrey, Christine, Spelman, Richard, Struchalin, Maksim, Thomas Johnson (363281), Ric Sherlock (511317), Mathew Littlejohn (4690033), Tiplady, Kathryn, Sherlock, Ric, Richard Spelman (387738), Lopdell, Thomas, Johnson, Thomas, Keehan, Michael, Michael Keehan (4690036), Snell, Russell   +21 more
core   +1 more source

The Impact of Tenapanor on Body Composition and Blood Pressure in Peritoneal Dialysis Patients: A Pilot Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Instruction Tenapanor potentially affects fluid volume and blood pressure. This study explored its effects on these parameters in patients undergoing peritoneal dialysis (PD). Methods We conducted a single‐arm, prospective observational study that enrolled 10 patients on PD with hyperphosphatemia who were newly initiated on tenapanor.
Shun Yoshida, Kengo Asahina, Keiichi Osano, Natsumi Saegusa, Kohei Yamamura, Kie Ohkoshi, Miho Shikata, Toshihisa Ishii, Makiko Konishi, Kazuya Takahashi, Kohei Uchimura, Ayumu Nakashima   +11 more
wiley   +1 more source

HD-and-RNA-variants-Chr5.vcf

, 2017
All HD and RNAseq variants on chromosome 5.
Thomas Lopdell (511314), Russell Snell (387740), Davis, Steve, Christine Couldrey (169434), Maksim Struchalin (166855), Steve Davis (5017841), Kathryn Tiplady (511313), Littlejohn, Mathew, Couldrey, Christine, Spelman, Richard, Struchalin, Maksim, Thomas Johnson (363281), Ric Sherlock (511317), Mathew Littlejohn (4690033), Tiplady, Kathryn, Sherlock, Ric, Richard Spelman (387738), Lopdell, Thomas, Johnson, Thomas, Keehan, Michael, Michael Keehan (4690036), Snell, Russell   +21 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

HD-and-RNA-variants-Chr2.vcf

, 2017
All HD and RNAseq variants on chromosome 2.
Thomas Lopdell (511314), Russell Snell (387740), Davis, Steve, Christine Couldrey (169434), Maksim Struchalin (166855), Steve Davis (5017841), Kathryn Tiplady (511313), Littlejohn, Mathew, Couldrey, Christine, Spelman, Richard, Struchalin, Maksim, Thomas Johnson (363281), Ric Sherlock (511317), Mathew Littlejohn (4690033), Tiplady, Kathryn, Sherlock, Ric, Richard Spelman (387738), Lopdell, Thomas, Johnson, Thomas, Keehan, Michael, Michael Keehan (4690036), Snell, Russell   +21 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Lee-Carter mortality forecasting: a multi-country comparison of variants and extensions [PDF]

We compare the short- to medium-term accuracy of five variants or extensions of the Lee-Carter method for mortality forecasting. These include the original Lee-Carter, the Lee-Miller and Booth-Maindonald-Smith variants, and the more flexible Hyndman ...
Heather Booth, Leonie Tickle, Piet de Jong, Rob J Hyndman   +3 more
core  

HD-and-RNA-variants-Chr4.vcf

, 2017
All HD and RNAseq variants on chromosome 4.
Thomas Lopdell (511314), Russell Snell (387740), Davis, Steve, Christine Couldrey (169434), Maksim Struchalin (166855), Steve Davis (5017841), Kathryn Tiplady (511313), Littlejohn, Mathew, Couldrey, Christine, Spelman, Richard, Struchalin, Maksim, Thomas Johnson (363281), Ric Sherlock (511317), Mathew Littlejohn (4690033), Tiplady, Kathryn, Sherlock, Ric, Richard Spelman (387738), Lopdell, Thomas, Johnson, Thomas, Keehan, Michael, Michael Keehan (4690036), Snell, Russell   +21 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source