Results 131 to 140 of about 92,807 (239)

Application and Challenges of Chimeric Antigen Receptor T Cell Therapy in Systemic Rheumatic Diseases and Autoimmune Disorders

open access: yesMedComm, Volume 7, Issue 4, April 2026.
CAR‐T cell therapy in systemic rheumatic diseases and autoimmune disorders. (This figure was created using BioRender.com.) ABSTRACT Chimeric antigen receptor T (CAR‐T) cell therapy, originally developed for hematologic malignancies, has emerged as a transformative candidate for systemic rheumatic diseases and autoimmune disorders (AIDs).
Zhidan Fan, Li Zhang, Haiguo Yu
wiley   +1 more source

Unraveling Chronic Pain: From Mechanisms and Risks to Diagnosis and Treatment

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Chronic pain arises through distinct molecular pathways categorized into nociceptive, neuropathic, and nociplastic types. Nociceptive pain begins with TRP channel activation in peripheral nociceptors, signaling via Aδ‐ and C‐fibers through the spinal dorsal horn and spinothalamic tracts to the brain, regulated by descending inhibition and involving ...
Xiaofeng Dai   +3 more
wiley   +1 more source

Tafasitamab as Monotherapy or in Combination in Japanese Patients With B‐Cell Non‐Hodgkin Lymphoma: Results From the Phase 1b J‐MIND Study

open access: yesCancer Science, Volume 117, Issue 4, Page 1093-1105, April 2026.
J‐MIND evaluated the safety and tolerability of tafasitamab, a CD19‐targeting monoclonal antibody, alone or in combination with other therapies in Japanese patients with B‐cell non‐Hodgkin lymphoma (NHL). Most common treatment‐emergent adverse events across all groups were hematological, and no serious tafasitamab treatment‐related or fatal adverse ...
Koji Izutsu   +7 more
wiley   +1 more source

Using qualitative methods to validate a stated preference survey for evaluating health services, CHERE Discussion Paper No 47 [PDF]

open access: yes
This study used a qualitative approach to assess parents? opinions of a self-completed stated preference discrete choice modelling (SPDCM) questionnaire for assessing the uptake of a new childhood vaccination against chickenpox. The aim was to assess the
Angela Yeoh   +4 more
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Factors Affecting Immune Reconstitution Post‐Allogeneic HSCT in Children: The Case for an Individualized Approach to Vaccination

open access: yesEuropean Journal of Haematology, Volume 116, Issue 4, Page 336-349, April 2026.
ABSTRACT Allogeneic hematopoietic stem cell transplantation (HSCT) is increasingly used to treat malignant and non‐malignant diseases. Following allogeneic HSCT, patients are particularly vulnerable to vaccine‐preventable diseases (VPD) because conditioning depletes immune cells, including memory cells.
Hélène Buvelot   +3 more
wiley   +1 more source

A time series study of the association between extreme temperature and ozone on varicella incidence

open access: yesScientific Reports
This study aimed to discuss the effects of extreme temperatures and ozone on the incidence of varicella in Shijiazhuang City from 2014 to 2022, which provides new ideas for preventing public health events.
Juan Zhang   +10 more
doaj   +1 more source

Varicella chorioretinitis [PDF]

open access: yesActa Ophthalmologica Scandinavica, 2007
Ozlem, Aslan   +2 more
openaire   +2 more sources

Impact of the BioFire FilmArray Meningitis‐Encephalitis Panel on Management of Suspected Paediatric Central Nervous System Infections: A Single‐Centre Retrospective Cohort Study

open access: yesJournal of Paediatrics and Child Health, Volume 62, Issue 4, Page 586-593, April 2026.
ABSTRACT Background Meningoencephalitis causes significant morbidity and mortality in children worldwide. Prompt diagnosis remains challenging, yet advances in molecular diagnostic technology have improved diagnostic performance. This study examined whether the introduction of the BioFire FilmArray meningitis/encephalitis (ME) multiplex panel impacted ...
Louisa Mary Churcher   +4 more
wiley   +1 more source

Does clinical exposure to different skin tones during training improve diagnostic ability?

open access: yesMedical Education, Volume 60, Issue 4, Page 410-417, April 2026.
Abstract Background Previous studies have shown that medical students demonstrate poorer performance when diagnosing pathology in skin of colour (SOC) compared to white skin (WS); it is important to understand the reasons underpinning this. If not addressed, poorer differential diagnostic ability in certain skin tones could entrench existing racial ...
Yusra Shammoon   +10 more
wiley   +1 more source

Strategies for the control and investigation of varicella outbreaks 2008 [PDF]

open access: yes
originally created 6/24/08; modified 12/8/17Following implementation of the one-dose varicella vaccination program in the United States in 1995, varicella vaccination coverage has steadily increased and the number of varicella cases has decreased ...

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