Results 31 to 40 of about 14,417 (236)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Effects of Different Rice Varieties and Water Management Practices on Greenhouse Gas (CH4 and N2O) Emissions in the Ratoon Rice System in the Upper Yangtze River Region, China

open access: yesAgriculture
Ratoon rice can improve rice yield by increasing the multiple cropping index in China. However, the greenhouse gas (CH4 and N2O) emission characteristics from ratoon rice fields and the cultivation methods to reduce CH4 and N2O emissions are rarely ...
Wujun Zhang   +6 more
doaj   +1 more source

Product of Local Points of Subvarieties of Almost Isotrivial Semi-Abelian Varieties Over a Global Function Field [PDF]

open access: yesInternational Mathematics Research Notices, 2012
For a semi-abelian variety over a global function field which is isogenous to an isotrivial one, we show that on the product of local points of a subvariety satisfying a minor condition, the topological closure of a finitely generated subgroup of %the group of its global points cuts out exactly the global points of the subvariety lying in this subgroup.
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Failure of the Brauer-Manin principle for a simply connected fourfold over a global function field, via orbifold Mordell

open access: yes, 2021
Almost one decade ago, Poonen constructed the first examples of algebraic varieties over global fields for which Skorobogatov's etale Brauer-Manin obstruction does not explain the failure of the Hasse principle.
Kebekus, Stefan   +2 more
core   +1 more source

Biotechnology: Two Decades of Experimentation with Genetically Modified Foods

open access: yesApplied Food Biotechnology, 2016
Background and Objective: Over the recent years, genetically modified food in varieties of corn, soybeans, canola and cotton have been introduced to the global market.
Marjan Ajami   +2 more
doaj  

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