Results 21 to 30 of about 26,969 (280)

Neutralization Determinants on Poxviruses

open access: yesViruses, 2023
Smallpox was a highly contagious disease caused by the variola virus. The disease affected millions of people over thousands of years and variola virus ranked as one of the deadliest viruses in human history. The complete eradication of smallpox in 1980,
Vernuccio Riccardo, Guardado-Calvo Pablo
doaj   +1 more source

The role of research in viral disease eradication and elimination programs: Lessons for malaria eradication [PDF]

open access: yes, 2011
By examining the role research has played in eradication or regional elimination initiatives for three viral diseases-smallpox, poliomyelitis, and measles-we derive nine cross-cutting lessons applicable to malaria eradication.
Breman, JG   +6 more
core   +1 more source

Ectromelia Virus Infections of Mice as a Model to Support the Licensure of Anti-Orthopoxvirus Therapeutics

open access: yesViruses, 2010
The absence of herd immunity to orthopoxviruses and the concern that variola or monkeypox viruses could be used for bioterroristic activities has stimulated the development of therapeutics and safer prophylactics.
R. Mark Buller   +4 more
doaj   +1 more source

Evaluation of Taterapox Virus in Small Animals

open access: yesViruses, 2017
Taterapox virus (TATV), which was isolated from an African gerbil (Tatera kempi) in 1975, is the most closely related virus to variola; however, only the original report has examined its virology.
Scott Parker   +3 more
doaj   +1 more source

The Virology of Taterapox Virus In Vitro

open access: yesViruses, 2018
Taterapox virus (TATV) is phylogenetically the closest related virus to variola—the etiological agent of smallpox. Despite the similarity, few studies have evaluated the virus.
Scott Parker   +8 more
doaj   +1 more source

Regulators of complement activity mediate inhibitory mechanisms through a common C3b‐binding mode [PDF]

open access: yes, 2016
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Atkinson, John P   +14 more
core   +2 more sources

Variola minor in coalfield areas of England and Wales, 1921–34: geographical determinants of a national smallpox epidemic that spread out of effective control [PDF]

open access: yes, 2017
This paper uses techniques of binary logistic regression to identify the spatial determinants of the last national epidemic of smallpox to spread in England and Wales, the variola minor epidemic of 1921–34.
Cliffe, Andrew   +2 more
core   +2 more sources

Avaliação de fungicidas no controle de Asperisporium caricae na cultura do mamoeiro

open access: yesRevista Brasileira de Fruticultura, 2011
Dentre as doenças fúngicas do mamoeiro, a varíola (Asperisporium caricae) é umas das doenças mais importantes. Os objetivos deste trabalho foram avaliar a eficácia de fungicidas no controle da varíola em folhas e frutos do mamoeiro.
Lívia Felício Barreto   +3 more
doaj   +1 more source

Vaccine Development against Infectious Diseases: State of the Art, New Insights, and Future Directions

open access: yesVaccines, 2023
In the 18th century, English physician Edward Jenner laid the foundation for modern vaccination by achieving protection against variola [...]
Fatima Conceição Silva   +2 more
doaj   +1 more source

Machine Learning‐Augmented Loop‐Mediated Isothermal Amplification‐Enabled Point‐of‐Care for Mpox‐Specific Detection

open access: yesAdvanced Intelligent Systems, EarlyView.
A low‐cost, portable point‐of‐care platform for rapid Mpox detection using loop‐mediated isothermal amplification is reported. The device integrates fluorescence readout and mobile monitoring. A machine‐learning model analyzes temperature data and correlates thermal changes with DNA concentration, enabling sensitive and reliable molecular diagnosis in ...
Nazente Atceken   +4 more
wiley   +1 more source

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