Results 121 to 130 of about 1,665,482 (247)
Viruses, 2016 In 2007, the United States– Food and Drug Administration (FDA) issued guidance concerning animal models for testing the efficacy of medical countermeasures against variola virus (VARV), the etiologic agent for smallpox.
Jennifer Garver +7 more
doaj +1 more source
Genome signatures, self-organizing maps and higher order phylogenies: a parametric analysis [PDF]
, 2007 Genome signatures are data vectors derived from the compositional statistics of DNA. The self-organizing map (SOM) is a neural network method for the conceptualisation of relationships within complex data, such as genome signatures.
Gatherer, Derek
core +4 more sources
Health Expectations, Volume 28, Issue 3, June 2025.ABSTRACT Background Limited data exists regarding long Covid burden following Omicron infection in highly vaccinated populations. Objective To (1) characterise long Covid prevalence and predictors and (2) identify key symptom clusters and their correlates among long Covid patients, during an Omicron‐predominant period in a highly vaccinated population.
Essa Tawfiq +9 more
wiley +1 more source
Variola virus E3L Zα domain, but not its Z-DNA binding activity, is required for PKR inhibition
RNA: A publication of the RNA Society, 2014 Diverse genetic and biochemical assays are used to conclude that the Z-DNA/RNA binding domain of the vaccinia E3L protein contributes to the interdiction of PKR activity, but that this function is not affected by mutations that disrupt Z-DNA binding.
M. Thakur, E. Seo, T. Dever
semanticscholar +1 more source
Studies of the Suitability of Fowlpox as a Decontamination and Thermal Stability Simulant for Variola Major [PDF]
, 2009 Variola major, the causative agent of smallpox, has been eradicated from nature. However, stocks still exist; thus, there is a need for relevant decontamination studies, preferably with nonpathogenic simulants. Previous studies have shown a similarity in
Chambers, Amanda E. +2 more
core +4 more sources
International Nursing Review, Volume 72, Issue 2, June 2025.ABSTRACT Aim To explore emergency room nurses’ perceptions of preparedness for bioterrorism. Introduction In the context of evolving global security threats, including wars, terrorism, and emerging infectious diseases, it is critical to evaluate the bioterrorism response competencies of emergency room nurses and identify strategies to enhance their ...
Mi‐Kyeong Jeon, Yujeong Kim
wiley +1 more source
Poxvirus Viability and Signatures in Historical Relics
Emerging Infectious Diseases, 2014 Although it has been >30 years since the eradication of smallpox, the unearthing of well-preserved tissue material in which the virus may reside has called into question the viability of variola virus decades or centuries after its original occurrence ...
Andrea M. McCollum +7 more
doaj +1 more source
Frontiers in Public HealthBiological threat agents such as Bacillus anthracis, Variola virus, and botulinum toxin pose serious risk to national security and public health due to their high transmissibility, lethality, and potential for weaponization.
Jungeun Lee
doaj +1 more source
mSphere, 2018 This article evaluates the scientific and commercial rationales for the synthesis of horsepox virus. I find that the claimed benefits of using horsepox virus as a smallpox vaccine rest on a weak scientific foundation and an even weaker business case that
Gregory D. Koblentz
doaj +1 more source
The Role of Brincidofovir in Preparation for a Potential Smallpox Outbreak
Viruses, 2017 Smallpox (variola) virus is considered a Category A bioterrorism agent due to its ability to spread rapidly and the high morbidity and mortality rates associated with infection. Current recommendations recognize the importance of oral antivirals and call
Scott A. Foster +2 more
doaj +1 more source