Results 91 to 100 of about 205,060 (282)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Global dataset of monthly growing areas of 26 irrigated crops : version 1.0

open access: yes, 2008
A data set of monthly growing areas of 26 irrigated crops (MGAG-I) and related crop calendars (CC-I) was compiled for 402 spatial entities. The selection of the crops consisted of all major food crops including regionally important ones (wheat, rice ...
Portmann, Felix Theodor   +3 more
core  

Safe Movement of ICRISAT’s Seed Crops Germplasm [PDF]

open access: yes, 2010
This information bulletin is a part of the report of the project- Global Public Goods II, Activity 3.1 entitled “Safe Movement of Seed Crops Germplasm and Protection of CGIAR Germplasm Banks”.
Rao, V P, Gunjotikar, G A, Thakur, R P
core  

THE USE OF SPRINKLER IRRIGATION IN CULTIVATION OF VARIOUS CROPS

open access: yesGalaxy International Interdisciplinary Research Journal, 2023
The article presents the optimal conditions for the development of crops, created during irrigation by pulsed sprinkling, which contributes to an increase in productivity up to 15-20%, which will solve the issues of ensuring the country's food security.
Djumanazarova Altingul Tengelovna   +1 more
openaire   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

The 2011 IPM Program of the Muck Crops Research Station

open access: yes, 2011
Integrated Pest Management (IPM) Summary ReportThe 2011 Integrated Pest Management (IPM) program for vegetable crops in the Holland Marsh, Ontario, was successfully provided by the University of Guelph, Muck Crops Research Station (MCRS) in cooperation ...
Tesfaendrias, Michael Tecle   +1 more
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Pollinator effectiveness and their potential for pollination of greenhouse crops in Kenya

open access: yes, 2011
Oronje MLA. Pollinator effectiveness and their potential for pollination of greenhouse crops in Kenya.
Oronje, Mary Lucy Adhiambo
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

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