Results 71 to 80 of about 881,071 (281)

Tables describing the use of various inputs during organic growing of important horticultural and arable crops across Europe [PDF]

open access: yes, 2018
This Annex presents the results of the survey carried out in the frame of Tasks 3.1. and Task 5.1 in the Organic PLUS project. A common table/questionnaire for both tasks was used in order to map the use of contentious inputs linked to plant protection ...
Katsoulas, Nikolaos, Løes, Anne-Kristin
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Integrated disease management [PDF]

open access: yes, 2006
Integrated disease management in organic farming combines the use of various measures. The usefulness of certain measures depends on the specific crop-pathogen combination.
Köhl, Jürgen
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Core reference sets of sorghum and musa : from a whole collection to a mini core collection and back (W291) [PDF]

open access: yes, 2011
The core approach for investigating genetic diversity in a crop germplasm collection has proven merits, among which the possibility to choose a sample of manageable size (e.g.
Arnaud, Elizabeth   +7 more
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Embedding Diversity: Communication and Label Concept for Underutilized Crops – Checklist for your First Evaluation [PDF]

open access: yes, 2018
There are some very successful cases of marketing of underutilized crops in European countries. Examples are the marketing of rare varieties in Austrian and Swiss supermarkets.
Förster, Iris   +2 more
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Modification of the existing maximum residue levels for penthiopyrad in stone fruits and cereals

open access: yesEFSA Journal, 2016
In accordance with Article 6 of Regulation (EC) No 396/2005, the evaluating Member States (EMS), France and Bulgaria, sent an application to modify the existing maximum residue levels (MRL) for the active substance penthiopyrad in apricots, peaches ...
European Food Safety Authority (EFSA)
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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