Results 101 to 110 of about 1,474,592 (383)

Role of Macrophages in the Progression and Regression of Vascular Calcification

Frontiers in Pharmacology, 2020
Vascular calcification is an abnormal cell-mediated process in which bone-specific hydroxyapatite crystals are actively deposited on the blood vessel wall and is a significant pathological basis for the increased incidence and mortality of adverse ...
Yalan Li, Zhen Sun, Lili Zhang, Jinchuan Yan, C. Shao, Lele Jing, Lihua Li, Zhongqun Wang   +7 more
semanticscholar   +1 more source

Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification

FEBS Open Bio, EarlyView.
Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski, Irene Cortijo, Shruti Bhargava, Bernard Jover, Fabrice Raynaud, Juliana H Boukhaled, Anne‐Dominique Lajoix, Vera Jankowski, Joachim Jankowski, Magali Cordaillat‐Simmons, Àngel Argilés, Nathalie Gayrard, Flore Duranton, Jonas Laget   +13 more
wiley   +1 more source

Relationship between Vascular Calcification, Protein-Energy Wasting Syndrome, and Sarcopenia in Maintenance Automated Peritoneal Dialysis

Life, 2021
Vascular calcifications affect 80% to 90% of chronic kidney disease patients and are a predictive factor of cardiovascular mortality. Sarcopenia and protein-energy wasting syndrome are also associated with mortality.
Gustavo Leal-Alegre, Claudia Lerma, Gabriela Leal-Escobar, Bernardo Moguel-González, Karen Belén Martínez-Vázquez, Karla Berenice Cano-Escobar   +5 more
doaj   +1 more source

A Lindera obtusiloba Extract Blocks Calcium-/Phosphate-Induced Transdifferentiation and Calcification of Vascular Smooth Muscle Cells and Interferes with Matrix Metalloproteinase-2 and Metalloproteinase-9 and NF-kB [PDF]

, 2015
Vascular calcifications bear the risk for cardiovascular complications and have a high prevalence among patients with chronic kidney disease. Central mediators of vascular calcifications are vascular smooth muscle cells (VSMC).
Freise, Christian, Kim, Ki Young, Querfeld, Uwe   +2 more
core   +1 more source

Regulation of Vascular Calcification by Reactive Oxygen Species

Antioxidants, 2020
Vascular calcification is the deposition of hydroxyapatite crystals in the medial or intimal layers of arteries that is usually associated with other pathological conditions including but not limited to chronic kidney disease, atherosclerosis and ...
A. Tóth, E. Balogh, V. Jeney
semanticscholar   +1 more source

Extensive vascular calcification

Indian Journal of Health Sciences and Biomedical Research (KLEU), 2015
Calciphylaxis denotes the presence of cutaneous gangrene secondary to the ischemic necrosis caused by vascular calcification. This is seen in patients with end stage renal disease, especially those using the renal replacement therapy. We recently encountered an elderly patient with long standing type 2 diabetes who presented with diabetic foot disease.
Mukesh Dhillon, K. V. S. Hari Kumar, Vipin Kwatra, Saurabh Dawra   +3 more
openaire   +3 more sources

Osteoprotegerin, vascular calcification and atherosclerosis [PDF]

Atherosclerosis, 2009
The association of bone pathologies with atherosclerosis has stimulated the search for common mediators linking the skeletal and the vascular system. Since its initial discovery as a key regulator in bone metabolism, osteoprotegerin (OPG) has become the subject of intense interest for its role in vascular disease and calcification. Studies in vitro and
Golledge, Jonathan, Van Campenhout, Ann
openaire   +4 more sources

Paroxysmal Dyskinesias Secondary to HHV‐6A Encephalitis: The First Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paroxysmal dyskinesias encompasses a spectrum of conditions marked by intermittent involuntary movements, with paroxysmal kinesigenic dyskinesias being the most common phenotype. Central nervous system infection is a rare cause of paroxysmal dyskinesias.
Zhuoran Wang, Haiting Li, Xiaoping Du, Qiong Wang, Yating Zhang, Huifang Wang   +5 more
wiley   +1 more source

Metabolic Consequences of Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry, Emily Sheng, Joshua F. Baker   +2 more
wiley   +1 more source

Resolution of Occlusive Carotid Artery Thrombus Treated with Anticoagulation as Demonstrated on Duplex Ultrasonography. [PDF]

, 2017
BACKGROUND AND PURPOSE: While the majority of cerebral ischemic events due to carotid occlusive disease result from atherosclerotic plaque rupture, intraluminal carotid artery thrombus occasionally occurs in patients without preexisting carotid ...
Liang, John W., Stein, Laura, Weinberger, Jesse   +2 more
core   +2 more sources