Results 201 to 210 of about 1,474,592 (383)

Vascular calcification in chronic kidney disease [PDF]

, 2004
William G. Goodman, Gérard M. London, Kerstin Amann, Geoffrey A. Block, Cecilia M. Giachelli, Keith A. Hruska, Markus Ketteler, Adeera Levin, Ziad A. Massy, David A. McCarron, Paolo Raggi, Catherine M. Shanahan, Noriaki Yorioka   +12 more
openalex   +1 more source

High phosphorus diet induces vascular calcification, a related decrease in bone mass and changes in the aortic gene expression [PDF]

, 2010
In chronic kidney disease, hyperphosphatemia has been associated to vascular calcifications. Moreover, the rate and progression of vascular calcification have been related with the reduction of bone mass and osteoporotic fractures, hereby suggesting a ...
Cannata, J.B. (Jorge), Carrillo, Natalia, Fernández, J.L. (José), Naves-Díaz, Manuel, Piedad, María, Román-García, Pablo   +5 more
core  

An Organ‐on‐Chip Platform for Strain‐Controlled, Tissue‐Specific Compression of Cartilage and Mineralized Osteochondral Interface to Study Mechanical Overloading in Osteoarthritis

Advanced Healthcare Materials, EarlyView.
A mechanically active OsteoChondral Unit (OCU)‐on‐Chip platform mimicking the OCU's functional anatomy and the strain gradient across the osteochondral interface is presented. Upon compartment‐specific hyperphysiological compression, the model replicates mechanisms observed in osteoarthritis (OA) progression, such as calcium crystal accumulation ...
Andrea Mainardi, Anastasiya Börsch, Paola Occhetta, Robert Ivanek, Martin Ehrbar, Lisa Krattiger, Philipp Oertle, Marko Loparic, Ivan Martin, Marco Rasponi, Andrea Barbero   +10 more
wiley   +1 more source

Correlation between serum trimethylamine oxide and vascular calcification in patients with chronic kidney disease

Linchuang shenzangbing zazhi
Objective To evaluate the associations between serum level of trimethylamine oxide （TMAO） and vascular calcification and explore the risk factors of vascular calcification in patients with chronic kidney disease （CKD）.
Pei-ru Gao, Cai-xia Cui, Xue-ping Wu, Wei-dong Chen   +3 more
doaj   +1 more source

Tumor Necrosis Factor-α Promotes In Vitro Calcification of Vascular Cells via the cAMP Pathway

, 2000
Yin Tintut, Jignesh Patel, Farhad Parhami, Linda L. Demer   +3 more
openalex   +1 more source

Engineering a Human‐Sized Common Bile Duct Prototype with Regenerative Potential: In Vitro Evaluation of Mechanics, Function, Degradation, and Immune Modulation

Advanced Healthcare Materials, EarlyView.
This study presents a multiphasic bile duct construct composed of biocompatible materials and cells, featuring an inner layer that supports biliary epithelium growth, a middle layer providing mechanical strength, and an outer cell‐permissive layer designed to support future in vivo integration.
Mattia Pasqua, Marianna Barbuto, Matteo Calligaris, Roberto Di Gesù, Duilio Pagano, Rosalia Busà, Salvatore Gruttadauria, Simone Dario Scilabra, Antonio D'Amore, Maria Giovanna Francipane   +9 more
wiley   +1 more source

Vascular calcification in patients with end-stage renal disease [PDF]

, 2004
J. Floege
openalex   +1 more source

Therapeutic Implants: Mechanobiologic Enhancement of Osteogenic, Angiogenic, and Myogenic Responses in Human Mesenchymal Stem Cells on 3D‐Printed Titanium Truss

Advanced Healthcare Materials, EarlyView.
This study investigates a synergistic effect between 3D‐printed surface features and mechanical micro‐strain in enhancing the osteogenic, angiogenic, and myogenic responses of human mesenchymal stem cells (hMSCs). Load‐induced mechanotransduction, facilitated by the implant's architectural design, significantly amplifies hMSC differentiation.
Se‐Hwan Lee, Ali Kiapour, Brendan D. Stoeckl, Ellen Y. Zhang, Matthew R. Begley, Jarod Oldham, Lewis Harrison, Jessee Hunt, Robert L. Mauck, Su Chin Heo   +9 more
wiley   +1 more source

Ultra‐Tiny Gelatin Nanoparticles‐Assisted 3D Stem Cell Spheroids for Engineering Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
GNPs effectively guide the formation of structurally compact and functionally enhanced stem cell spheroids. This GNP‐assisted 3D culture system improves cell–cell and cell‐ECM interactions, leading to superior viability and complexity. Time‐dependent regenerative potential is demonstrated in both bone and skin defects, positioning GNP‐spheroids as a ...
Dream Kim, Woochan Kim, Harshita Sharma, Shinyull Lee, Chaeyeon Park, Sunho Park, Chan Yeong Heo, Jangho Kim   +7 more
wiley   +1 more source

Antibiotic-induced gut microbiota disruption promotes vascular calcification by reducing short-chain fatty acid acetate

Molecular Medicine
Background Vascular calcification is a common vascular lesion associated with high morbidity and mortality from cardiovascular events. Antibiotics can disrupt the gut microbiota (GM) and have been shown to exacerbate or attenuate several human diseases ...
Shi-Yu Zeng, Yi-Fu Liu, Zhao-Lin Zeng, Zhi-Bo Zhao, Xi-Lin Yan, Jie Zheng, Wen-Hang Chen, Zhen-Xing Wang, Hui Xie, Jiang-Hua Liu   +9 more
doaj   +1 more source