Results 201 to 210 of about 126,547 (360)

Protein‐Like Polymers Targeting Keap1/Nrf2 as Therapeutics for Myocardial Infarction

Advanced Materials, EarlyView.
We describe a Keap1 targeting protein‐like polymer (PLP) which activates Nrf2, an important cytoprotective transcription factor for relieving myocardial infarction‐induced oxidative stress. This PLP increases cell survival in vitro in multiple relevant cardiac cell types and elicits pro‐reparative responses, improving cardiac function in a preclinical ...
Joshua M. Mesfin, Kendal P. Carrow, Alexander Chen, Madeline P. Hopps, JoJo J. Holm, Quincy P. Lyons, Michael B. Nguyen, Jervaughn D. Hunter, Assa Magassa, Elyse G. Wong, Kate Reimold, Sriya N. Paleti, Emily Gardner, Matthew P. Thompson, Colin G. Luo, Xiaoyu Zhang, Karen L. Christman, Nathan C. Gianneschi   +17 more
wiley   +1 more source

Materials Advances in Devices for Heart Disease Interventions

Advanced Materials, EarlyView.
This review examines the crucial role of materials in heart disease interventions, focusing on strategies for monitoring, managing, and repairing heart conditions. It discusses the material requirements for medical devices, highlighting recent innovations and their impact on cardiovascular health.
Gagan K. Jalandhra, Lauryn Srethbhakdi, James Davies, Chi Cong Nguyen, Phuoc Thien Phan, Zachary Och, Aditya Ashok, Khoon S. Lim, Hoang‐Phuong Phan, Thanh Nho Do, Nigel H. Lovell, Jelena Rnjak‐Kovacina   +11 more
wiley   +1 more source

Vascular wall microenvironment: Endothelial cells original exosomes mediated melatonin-suppressed vascular calcification and vascular ageing in a m6A methylation dependent manner

Bioactive Materials
Vascular calcification and vascular ageing are “silent” diseases but are highly prevalent in patients with end stage renal failure and type 2 diabetes, as well as in the ageing population. Melatonin (MT) has been shown to induce cardiovascular protection
Su-Kang Shan, Xiao Lin, Feng Wu, Chang-Chun Li, Bei Guo, Fu-Xing-Zi Li, Ming-Hui Zheng, Yi Wang, Qiu-Shuang Xu, Li-Min Lei, Ke-Xin Tang, Yun-Yun Wu, Jia-Yue Duan, Ye-Chi Cao, Yan-Lin Wu, Chang-Ming Tan, Zi-Han Liu, Zhi-Ang Zhou, Xiao-Bo Liao, Feng Xu, Ling-Qing Yuan   +20 more
doaj  

Hybrid roles of adaptation and optimization in formation of vascular network [PDF]

arXiv
It was hypothesized that the structures of biological transport networks are the result of either energy consumption or adaptation dynamics. Although approaches based on these hypotheses can produce optimal network and form loop structures, we found that neither possesses complete ability to generate complex networks that resemble vascular network in ...
arxiv  

Vascular calcification in chronic kidney disease [PDF]

, 2004
William G. Goodman, Gérard M. London, Kerstin Amann, Geoffrey A. Block, Cecilia M. Giachelli, Keith A. Hruska, Markus Ketteler, Adeera Levin, Ziad A. Massy, David A. McCarron, Paolo Raggi, Catherine M. Shanahan, Noriaki Yorioka   +12 more
openalex   +1 more source

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

Advanced Materials, EarlyView.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi, Yadi Fan, Qin Zhang, Yingying Huang, Mo Yang   +4 more
wiley   +1 more source

Haralick texture feature analysis for Monte Carlo dose distributions of permanent implant prostate brachytherapy [PDF]

arXiv
Purpose: Demonstrate quantitative characterization of 3D patient-specific absorbed dose distributions using Haralick texture analysis and interpret measures in terms of underlying physics and radiation dosimetry. Methods: Retrospective analysis is performed for 137 patients who underwent permanent implant prostate brachytherapy using two simulation ...
arxiv  

Vascular calcification in patients with end-stage renal disease [PDF]

, 2004
J. Floege
openalex   +1 more source

Bioactive Glass Microscaffolds Fabricated by Two‐Photon Lithography

Advanced Materials, EarlyView.
Microstructuring of bioactive glasses offers great potential to influence cell behavior for bone tissue engineering. By utilizing two‐photon lithography of a nanocomposite and thermal post‐processing, single‐micron features and complex structures are achieved.
Leonhard Hambitzer, Jan Mathis Hornbostel, Louise Roolfs, Richard Prediger, Sebastian Kluck, Kai Zheng, Cornelia Lee‐Thedieck, Frederik Kotz‐Helmer   +7 more
wiley   +1 more source

Enhancing Coronary Artery Calcium Scoring via Multi-Organ Segmentation on Non-Contrast Cardiac Computed Tomography [PDF]

arXiv
Despite coronary artery calcium scoring being considered a largely solved problem within the realm of medical artificial intelligence, this paper argues that significant improvements can still be made. By shifting the focus from pathology detection to a deeper understanding of anatomy, the novel algorithm proposed in the paper both achieves high ...
arxiv