Results 11 to 20 of about 2,053,431 (310)

Understanding vascular development [PDF]

open access: yesWIREs Developmental Biology, 2012
AbstractThe vasculature of an organism has the daunting task of connecting all the organ systems to nourish tissue and sustain life. This complex network of vessels and associated cells must maintain blood flow, but constantly adapt to acute and chronic changes within tissues.
Ryan S, Udan   +2 more
openaire   +2 more sources

GTP-Binding Protein 1-Like (GTPBP1l) Regulates Vascular Patterning during Zebrafish Development

open access: yesBiomedicines, 2022
Genetic regulation of vascular patterning is not fully understood. Here, we report a novel gene, gtpbp1l (GTP-binding protein 1-like), that regulates vascular development in zebrafish.
Yi-Hao Lo   +8 more
doaj   +1 more source

Spatio-temporal imaging of cell fate dynamics in single plant cells using luminescence microscope

open access: yesQuantitative Plant Biology, 2022
Stem cell fates are spatio-temporally regulated during plant development. Time-lapse imaging of fluorescence reporters is the most widely used method for spatio-temporal analysis of biological processes. However, excitation light for imaging fluorescence
Shunji Shimadzu   +4 more
doaj   +1 more source

One-Step In Vitro Generation of ETV2-Null Pig Embryos

open access: yesAnimals, 2022
Each year, tens of thousands of people worldwide die of end-stage organ failure due to the limited availability of organs for use in transplantation. To meet this clinical demand, one of the last frontiers of regenerative medicine is the generation of ...
Marta Moya-Jódar   +16 more
doaj   +1 more source

Probing the Effects of the FGFR-Inhibitor Derazantinib on Vascular Development in Zebrafish Embryos

open access: yesPharmaceuticals, 2020
Angiogenesis is a fundamental developmental process and a hallmark of cancer progression. Receptor tyrosine kinases (RTK) are targets for cancer therapy which may include their action as anti-angiogenic agents.
Maria P. Kotini   +4 more
doaj   +1 more source

Peptide Signaling Pathways Regulate Plant Vascular Development

open access: yesFrontiers in Plant Science, 2021
Plant small peptides, including CLAVATA3/EMBRYO SURROUNDING REGION-RELATED (CLE) and Epidermal Patterning Factor-Like (EPFL) peptides, play pivotal roles in coordinating developmental processes through cell-cell communication.
Bingjian Yuan   +2 more
doaj   +1 more source

Identification of Novel Vascular Genes Downstream of Islet2 and Nr2f1b Transcription Factors

open access: yesBiomedicines, 2022
The genetic regulation of vascular development is not elucidated completely. We previously characterized the transcription factors Islet2 (Isl2) and Nr2f1b as being critical for vascular growth.
Ru-Fang Li   +6 more
doaj   +1 more source

Integrins in Vascular Development [PDF]

open access: yesCirculation Research, 2001
In recent years, there has been a sustained interest in vascularization processes. Much, if not all, of the work has included the concept of new vessel morphogenesis. Surprisingly, most of the work has not addressed developmental mechanisms directly, but rather as an offshoot of a disease process, wound healing process, or from the perspective of ...
P A, Rupp, C D, Little
openaire   +2 more sources

Highly Efficient Synthetic CRISPR RNA/Cas9-Based Mutagenesis for Rapid Cardiovascular Phenotypic Screening in F0 Zebrafish

open access: yesFrontiers in Cell and Developmental Biology, 2021
The zebrafish is a valuable vertebrate model to study cardiovascular formation and function due to the facile visualization and rapid development of the circulatory system in its externally growing embryos.
Rachael E. Quick   +9 more
doaj   +1 more source

Ifi30 Is Required for Sprouting Angiogenesis During Caudal Vein Plexus Formation in Zebrafish

open access: yesFrontiers in Physiology, 2022
Interferon-gamma-inducible protein 30 (IFI30) is a critical enzyme that mainly exists in immune cells and functions in reducing protein disulfide bonds in endocytosis-mediated protein degradation.
Xiaoning Wang   +4 more
doaj   +1 more source

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