Results 71 to 80 of about 10,815,340 (358)

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Temporal Evolution of Left Main Coronary Artery Stenosis De Novo Presentation: Trends in Coronary Angiography and Clinical Characteristics (LM-EVOLUTION Study)

Journal of Interventional Cardiology
Conclusions: In consecutive patients presenting with de novo LM stenosis, angiographic SS showed a statistically significant negative trend over a decade, driven primarily by a reduction in non-LM-SS.
Jakub Chmiel, Kacper Miłosz Książek, Jagoda Dradrach, Grażyna Wnuk, Krzysztof Piotr Malinowski, Karol Musiał, Władysław Dąbrowski, Łukasz Czyż, Paweł Iwaszczuk, Kenneth Rosenfield, Piotr Musiałek   +10 more
doaj   +1 more source

Nanoparticle Therapy for Vascular Diseases

Arteriosclerosis, Thrombosis and Vascular Biology, 2019
Nanoparticles promise to advance strategies to treat vascular disease. Since being harnessed by the cancer field to deliver safer and more effective chemotherapeutics, nanoparticles have been translated into applications for cardiovascular disease ...
Alyssa M. Flores, Jianqin Ye, K. Jarr, Niloufar Hosseini-Nassab, B. Smith, N. Leeper   +5 more
semanticscholar   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

The light and shadow of senescence and inflammation in cardiovascular pathology and regenerative medicine [PDF]

, 2017
Recent epidemiologic studies evidence a dramatic increase of cardiovascular diseases, especially associated with the aging of the world population. During aging, the progressive impairment of the cardiovascular functions results from the compromised ...
Cavarretta, Elena, Dal Sasso, Eleonora, Forte, Maurizio, Frati, Giacomo, Gerosa, Gino, Iop, Laura, Palmerio, Silvia, Peruzzi, Mariangela, Schirone, Leonardo, Sciarretta, Sebastiano   +9 more
core   +4 more sources

Regulation of T cell afferent lymphatic migration by targeting LTβR-mediated non-classical NFκB signaling

Nature Communications, 2018
Lymphotoxin beta receptor (LTβR) signalling regulates leukocyte migration through the lymphatic endothelial layers. Here, the authors show that treatment of an LTβR-derived decoy peptide can target the non-classical NFκB pathway to inhibit T cell and ...
Wenji Piao, Yanbao Xiong, Konrad Famulski, C. Colin Brinkman, Lushen Li, Nicholas Toney, Chelsea Wagner, Vikas Saxena, Thomas Simon, Jonathan S. Bromberg   +9 more
doaj   +1 more source

The original and two new derivative versions of the COMPERA 2.0 risk assessment model: useful tools for guiding balloon pulmonary angioplasty

Respiratory Research, 2022
Background The COMPERA 2.0 4-stratum (4-S) risk score has been demonstrated superior over the 3-stratum (3-S) one in patients with pulmonary arterial hypertension and medically managed patients with chronic thromboembolic pulmonary hypertension (CTEPH ...
Yi Zhang, Xin Li, Qi Jin, Qin Luo, Qing Zhao, Tao Yang, Qixian Zeng, Lu Yan, Anqi Duan, Zhihua Huang, Meixi Hu, Changming Xiong, Zhihui Zhao, Zhihong Liu   +13 more
doaj   +1 more source

Vascular Diseases In Patients With Chronic Myeloproliferative Neoplasms – Impact Of Comorbidity

Clinical Epidemiology, 2019
Background Patients with chronic myeloproliferative neoplasms (MPNs), including essential thrombocythemia (ET), polycythemia vera (PV), and primary myelofibrosis (PMF), are at high risk of vascular complications.
H. Frederiksen, S. Szépligeti, M. Bak, W. Ghanima, H. Hasselbalch, C. Christiansen   +5 more
semanticscholar   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Alzheimer and vascular brain disease: Senile dementia. [PDF]

, 2015
Alois Alzheimer is best known for his description of a novel disease, subsequently named after him. However, his wide range of interests also included vascular brain diseases.
Engelhardt, Eliasz, Grinberg, Lea T
core   +2 more sources