Results 41 to 50 of about 27,631,015 (306)

Cerebral and systemic endothelial dysfunction in migraine: Current knowledge and perspective [PDF]

Romanian Journal of Neurology, 2021
Migraine still causes a high rate of disability and is reported to increase the risk of cardiovascular and cerebrovascular diseases. Endothelial dysfunction is considered to be one of the underlying mechanisms linking migraine and vascular disorders ...
I Made Oka Adnyana, Valentina Tjandra Dewi   +1 more
doaj   +1 more source

Shear Stress Induces the Release of an Endothelial Elastase: Role in Integrin alpha(v)beta(3)-Mediated FGF-2 Release [PDF]

, 2011
Background/Aims: Laminar shear stress is an important stimulus in the endothelium-dependent control of vascular tone and of vascular remodeling processes.
Hennig, Theres, Christina Mogensen, Gloe, Torsten, Kirsch, Julian, Julian Kirsch, Torsten Gloe, Ulrich Pohl, Pohl, Ulrich, Theres Hennig, Mogensen, Christina   +9 more
core   +1 more source

Vascular endothelial growth factor +405G/C polymorphism as a predictor of diabetic retinopathy

Bulletin of the National Research Centre, 2020
Background Diabetic retinopathy is a multistage event, and the most important of it is angiogenesis. The possible association between vascular endothelial growth factor (VEGF) +405G/C gene polymorphism and various diseases, in which angiogenesis might be
Azza K. Amer, Nervana A. Khalaf, Safia H. Aboelmakarem, Mehry S. Elsobky, Mona R. Abdelrasoul, Amira A. Abdelazeem, Shahira R. Noweir, Safa Refaat, Leqaa A. Moemen, Soheir A. Mohammed, Mona A. Abdelhameed, Mohmoud M. Kenawy, Manal H. Abuelela, Marwa A. Fouly, Olfat A. Hassanin, Sherif M. Saadeldin Karawya, Zeinab M. Osman   +16 more
doaj   +1 more source

Lymphangiogenic Markers and Their Impact on Nodal Metastasis and Survival in Non-Small Cell Lung Cancer--A Structured Review with Meta-Analysis. [PDF]

PLoS ONE, 2015
In non-small cell lung cancer (NSCLC), nodal metastasis is an adverse prognostic factor. Several mediating factors have been implied in the development of nodal metastases and investigated for predictive and prognostic properties in NSCLC. However, study
Thomas K Kilvaer, Erna-Elise Paulsen, Sigurd M Hald, Tom Wilsgaard, Roy M Bremnes, Lill-Tove Busund, Tom Donnem   +6 more
doaj   +1 more source

Vascular endothelial growth factor‐C‐mediated lymphangiogenesis promotes tumour metastasis [PDF]

The EMBO Journal, 2001
Metastasis is a frequent and lethal complication of cancer. Vascular endothelial growth factor-C (VEGF-C) is a recently described lymphangiogenic factor. Increased expression of VEGF-C in primary tumours correlates with dissemination of tumour cells to regional lymph nodes.
Mandriota, Stefano Jacopo, Jussila, Lotta, Jeltsch, Michael, Compagni, Amelia, Baetens Baumann, Danielle, Prevo, Remko, Banerji, Suneale, Huarte, Joachim, Montesano, Roberto, Jackson, David G., Orci, Lelio, Alitalo, Kari, Christofori, Gerhard, Pepper, Michael Sean   +13 more
openaire   +2 more sources

CD8 T-cell induction against vascular endothelial growth factor receptor 2 by Salmonella for vaccination purposes against a murine melanoma. [PDF]

, 2012
The Salmonella type III secretion system (T3SS) efficiently translocates heterologous proteins into the cytosol of eukaryotic cells. This leads to an antigen-specific CD8 T-cell induction in mice orally immunized with recombinant Salmonella. Recently, we
Jellbauer, Stefan, Hetrodt, Justin H., Justin H Hetrodt, Rüssmann, Holger, Stefan Jellbauer, Klaus Panthel, Holger Rüssmann, Panthel, Klaus, Rüssmann Holger, Panthel Klaus, Jellbauer Stefan, Hetrodt Justin H.   +11 more
core   +2 more sources

Two Birds, One Stone: Double Hits on Tumor Growth and Lymphangiogenesis by Targeting Vascular Endothelial Growth Factor Receptor 3

Cells, 2019
Vascular endothelial growth factor receptor 3 (VEGFR3) has been known for its involvement in tumor-associated lymphangiogenesis and lymphatic metastasis. The VEGFR3 signaling is stimulated by its main cognate ligand, vascular endothelial growth factor C (
Ming-Chuan Hsu, Mei-Ren Pan, Wen-Chun Hung   +2 more
doaj   +1 more source

Serum vascular endothelial growth factors C and D in patients with oesophageal cancer☆☆☆ [PDF]

European Journal of Cardio-Thoracic Surgery, 2010
Lymph node metastasis is a characteristic of malignant cancers and is observed more frequently in oesophageal cancer than in other digestive tract cancers, making it one of the most important prognostic factors. Vascular endothelial growth factors C (VEGF-C) and D (VEGF-D) are important lymphangiogenic factors in human cancers and lymphangiogenesis is ...
Mirosław Kozłowski, Oksana Kowalczuk, Robert Milewski, Chyczewski, Lech, Jacek Nikliński, Laudański, Jerzy   +5 more
openaire   +3 more sources

Kolaviron shows anti-proliferative effect and down regulation of vascular endothelial growth factor-C and toll like receptor-2 in Wuchereria bancrofti infected blood lymphocytes

Journal of Infection and Public Health, 2017
The anti-proliferative effect and down regulation of vascular endothelial growth factor C and toll like receptor-2 by kolaviron on Wuchereria bancrofti infected peripheral blood lymphocytes were investigated.
Aliyu Muhammad, Audu Funmilola, Idowu A. Aimola, Iliya S. Ndams, Mairo H. Inuwa, Andrew J. Nok   +5 more
doaj   +1 more source

Vascular endothelial growth factor C is increased in endometrium and promotes endothelial functions, vascular permeability and angiogenesis and growth of endometriosis

Angiogenesis, 2013
Endometriosis is an angiogenesis-dependent disease. Many studies demonstrated inhibition of angiogenesis leads to inhibition of endometriotic growth, however underlying mechanism is still not fully understood. Our previous study suggested vascular endothelial growth factor C (VEGF-C) as a target of anti-angiogenesis therapy for endometriosis.
Xu, Hui, Zhang, Tao, Man, Gene Chi Wai, Maiden_Name, Katie E, Becker, Christian M, Davis, Tina N, Kung, Andrew L, Birsner, Amy E, D'Amato, Robert J, Wong, Alice Wai Yee, Wang, Chi Chiu   +10 more
openaire   +4 more sources