Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner +8 more
wiley +1 more source
Glomerular ultrastructural change and vascular endothelial growth factor-A expression in diabetic cats. [PDF]
Reyes-Hughes H +6 more
europepmc +1 more source
A bone substitute with gentamicin physically precipitated onto the surface of carbonate apatite exhibits prompt drug release, high bactericidal activity, and osteogenic capacity. Efficient antibacterial activity mitigates early postoperative neutrophil accumulation, the status of which may serve as a potential parameter for evaluating the antibacterial
Linghao Xiao +6 more
wiley +1 more source
Ultrasound Biomicroscopy of Patients With Hemorrhagic Complications Following Intravitreal Anti-Vascular Endothelial Growth Factor Injection. [PDF]
Antonietti M +3 more
europepmc +1 more source
The comparative analysis of Vascular Endothelial Growth Factor-A (VEGF-A) impacts in Ovarian Hyper Stimulation Syndrome and Obesity [PDF]
Fatemeh Rahimianfar
openalex +1 more source
Advances in Bioprinting to Model Immune‐Mediated Skin Diseases
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández +4 more
wiley +1 more source
Retraction: "Levels of vascular endothelial growth factor and matrix metalloproteinase-9 proteins in patients with glioma". [PDF]
europepmc +1 more source
Vascular Endothelial Growth Factor Receptor 2-Targeted Therapy Suppresses the Progression of Alpha-Fetoprotein-Positive Hepatocellular Carcinoma After Combination Therapy With Anti-Programmed Death-Ligand 1 and Anti-Vascular Endothelial Growth Factor-A Antibodies. [PDF]
Sugiyama G +16 more
europepmc +1 more source
In ophthalmology, living biomaterials such as living contact lenses appear promising for sustained drug delivery or biosensing. The cytocompatibility of Cg‐PVA hydrogels, developed as a model living contact lens, is investigated with the ocular surface, showing their potential translation to the clinic.
Krupansh Desai +6 more
wiley +1 more source

