Results 331 to 340 of about 855,799 (394)

Vascular Endothelial Growth Factor and Angiogenesis

Pharmacological Reviews, 2004
Angiogenesis is a hallmark of wound healing, the menstrual cycle, cancer, and various ischemic and inflammatory diseases. A rich variety of pro- and antiangiogenic molecules have already been discovered. Vascular endothelial growth factor (VEGF) is an interesting inducer of angiogenesis and lymphangiogenesis, because it is a highly specific mitogen for
Ann, Hoeben, Bart, Landuyt, Martin S, Highley, Hans, Wildiers, Allan T, Van Oosterom, Ernst A, De Bruijn   +5 more
openaire   +3 more sources

Vascular Endothelial Growth Factor A in Intraocular Vascular Disease

Ophthalmology, 2013
The vascular beds supplying the retina may sustain injury as a result of underlying disease such as diabetes, and/or the interaction of genetic predisposition, environmental insults, and age. The vascular pathologic features observed in different intraocular vascular diseases can be categorized broadly as proliferation, exemplified by proliferative ...
Joan W, Miller, Jennifer, Le Couter, Erich C, Strauss, Napoleone, Ferrara   +3 more
openaire   +3 more sources

Vascular endothelial growth factor

Journal of Neuro-Oncology, 1997
Vascular endothelial growth factor (VEGF) is a hypoxia-inducible angiogenesis and vascular permeability factor which is expressed in high amounts in perinecrotic palisading cells in human glioblastomas. In vitro VEGF gene expression is enhanced approximately ten times by hypoxia.
Plate, Karlheinz, Warnke, Peter C.
openaire   +2 more sources

Vascular Endothelial Growth Factor

Ceskoslovenska fysiologie, 2012
VEGF, vascular endothelial growth factor, is a substance firstly described in 1983 as a tumor-secreted protein which causes the development of ascitic fluid in case of abdominal tumors. Its influence on angiogenesis was ascertained by many studies. The strongest stimulus for its production is hypoxia, which leads to higher secretion of VEGF and new ...
R, Kaiser, P, Dubový, P, Haninec
  +5 more sources

Vascular Endothelial Growth Factor

2003
The striking structural and anatomical parallels between the vasculature and the nervous system is reflected by the fact that these two organ systems appear to use related mechanisms during their development. Thus, it is not surprising that an increasing number of vascular biologists and researchers in the neuroscience field are fascinated by molecules
D GABRILOVICH, M DIKOV
openaire   +3 more sources

Vascular Endothelial Growth Factor and Vascular Homeostasis

Proceedings of the American Thoracic Society, 2011
Vascular endothelial growth factor (VEGF) is the angiogenic factor promoting and orchestrating most, if not all, processes of neovascularization taking place in the embryo and the adult. VEGF is also required to sustain newly formed vessels and plays additional multiple roles in the maintenance and function of certain mature vascular beds ...
Alon, Lazarus, Eli, Keshet
openaire   +2 more sources

Vascular endothelial growth factor

Ophthalmology, 2007
Vascular endothelial growth factor (VEGF) signalling is a key stimulant of tumour neovascular growth, survival and capillary permeability, which are critical to solid tumour progression. The intracellular signalling responses that induce an angiogenic phenotype are dependent upon VEGF binding to specific transmembrane receptors on the endothelium and ...
Neil Swanson, Anthony Gershlick
  +4 more sources