Results 41 to 50 of about 706,179 (309)

Hypoxia-induced reactive oxygen species cause chromosomal abnormalities in endothelial cells in the tumor microenvironment. [PDF]

PLoS ONE, 2013
There is much evidence that hypoxia in the tumor microenvironment enhances tumor progression. In an earlier study, we reported abnormal phenotypes of tumor-associated endothelial cells such as those resistant to chemotherapy and chromosomal instability ...
Miyako Kondoh, Noritaka Ohga, Kosuke Akiyama, Yasuhiro Hida, Nako Maishi, Alam Mohammad Towfik, Nobuo Inoue, Masanobu Shindoh, Kyoko Hida   +8 more
doaj   +1 more source

VEGF is indirectly associated with NO production

, 2012
Background? Increased levels of vascular endothelial growth factor (VEGF) have been observed in patients with metabolic syndrome (MetS). Nitric oxide (NO) formation is reduced in MetS, but its relationship to VEGF production remains poorly defined.
Alberti, Barylski, Bergman, Birk, Blann, Cao, Conover, Doupis, Dullaart, Ersoy, Hagberg, Jackson, Jackson, Kakizawa, Kimura, Kimura, Loebig, Sandhofer, Siervo, Siervo, Siervo, Siervo, Siervo, Silha, Simera, Treins, Tsai, Valabhji, Vyzantiadis   +28 more
core   +1 more source

Circulating protein biomarkers in systemic sclerosis related pulmonary arterial hypertension: a review of published data [PDF]

, 2018
Pulmonary arterial hypertension (PAH) develops in 7-12% of patients with systemic sclerosis (SSc) and is associated with a 3 year survival of 52%. Early detection by screening is therefore recommended for all patients with SSc.
Adela, Andreassen, Angelini, Avouac, Boucly, Cacoub, Chung, Coghlan, Coghlan, Condliffe, Conley, Coral-Alvarado, Eddahibi, Fijalkowska, Gore, Hachulla, Hoeper, Humbert, Kylhammar, Lau, Lefèvre, Leuchte, Machado, Mathai, McMahan, Meadows, Mercié, Mukerjee, Nagaya, Nickel, Nickel, Nickel, Olsson, Overbeek, Papaioannou, Park, Ramjug, Rhee, Shibuya, Stratton, Strimbu, Tyndall, Vandecasteele, Voelkel, Warwick, Williams   +45 more
core   +2 more sources

Serum vascular endothelial growth factor: a prognostic factor in cervical cancer [PDF]

Journal of Cancer Research and Clinical Oncology, 2008
To study pre-treatment serum VEGF of patients with invasive cervical cancer and its possible role as prognostic indicator.VEGF was measured using ELISA in the largest patient group (n = 167) to date.Serum VEGF was significantly higher in advanced tumor stage (P = 0.01), large tumor size (tumors larger than 2 cm) (P = 0.03), and the presence of vascular
Zusterzeel, P.L.M., Span, P.N., Dijksterhuis, M.G., Thomas, C.M.G., Sweep, C.G.J., Massuger, L.F.A.G.   +5 more
openaire   +3 more sources

VEGF-A isoforms differentially regulate ATF-2-dependent VCAM-1 gene expression and endothelial-leukocyte interactions [PDF]

, 2014
Vascular endothelial growth factor A (VEGF-A) regulates many aspects of vascular physiology. VEGF-A stimulates signal transduction pathways that modulate endothelial outputs such as cell migration, proliferation, tubulogenesis, and cell-cell interactions.
Abid MR, Abid MR, Adam F. Odell, Alexander F. Bruns, Antony M. Latham, Arthur JS, Baker M, Bartoli M, Bates DO, Bruns AF, Bruns AF, Butler JM, Carl-Henrik Heldin, Carmeliet P, Chen TT, Chung AS, Collins T, Cuhlmann S, Dejana E, Delcombel R, Ding BS, Ewan LC, Fearnley GW, Gareth W. Fearnley, Gerits N, Goddard LM, Griffioen AW, Harper SJ, Herve MA, Holmqvist K, Hordijk PL, Horowitz A, Howell GJ, Ian C. Zachary, Jain RK, Jopling HM, Jopling HM, Karihaloo A, Kawasaki H, Kawasaki H, Keyt BA, Kim I, Kim I, Koch S, Koch S, Lau E, Lemmon MA, Liu D, Meadows KL, Melder RJ, Monica C. Hollstein, Nadeem A. Mughal, Nakatsu MN, Nakayama M, Naldini A, Nicholas J. Burgoyne, Nourshargh S, Pan Q, Panne D, Plotnikov A, Reglero-Real N, Reimold AM, Rivera CG, Salameh A, Schweighofer B, Seko Y, Shalaby F, Shervanthi Homer-Vanniasinkam, Sixt M, Sreenivasan Ponnambalam, Stannard AK, Stephen B. Wheatcroft, Takahashi T, Testori J, Usui T, Weber C, Xu D, Zhang HT, Zhang Y   +78 more
core   +3 more sources

Investigation of the mechanism of dural arteriovenous fistula formation induced by high intracranial venous pressure in a rabbit model [PDF]

, 2014
BACKGROUND: The causes of dural arteriovenous fistula have not been clearly defined. The aim of this study was to investigate the mechanism of dural arteriovenous fistula formation induced by high intracranial venous pressure using a rabbit model ...
Chang-Hua Li, Ru-Mi Wang, Shou-Sen Wang, Xiao-Jun Zhang   +3 more
core   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Vascular endothelial growth factor in relation to the development of hepatocellular carcinoma in hepatitis C virus patients treated by direct-acting antivirals

Egyptian Liver Journal, 2021
Background Hepatocellular carcinoma (HCC) comprises 5.6% of all cancers worldwide representing the sixth most common cancer. It is also the fourth most common cause of cancer-related mortality.
Ahmed Mohamed ElGhandour, Essam Mohamed Bayoumy, Wesam Ahmed Ibrahim, Moataz Mohamed Sayed, Ashraf Bekheet Salama, Nahla Mohamed Teama, Mohamed Magdy Salama   +6 more
doaj   +1 more source

A peptide derived from TIMP-3 inhibits multiple angiogenic growth factor receptors and tumour growth and inflammatory arthritis in mice [PDF]

, 2013
The binding of vascular endothelial growth factor (VEGF) to VEGF receptor-2 (VEGFR-2) on the surface of vascular endothelial cells stimulates many steps in the angiogenic pathway.
A Janssen, A Kim, A Tuuttila, Ahmed H. Mujamammi, B AnandApte, C Alam, C Fischer, CA Bootle-Wilbraham, CA Staton, Claire E. Lewis, D Matei, DR Robinson, DW Seo, F Kazazi-Hyseni, FX Gomis-Ruth, G Bergers, G Fassina, G Fuh, H Gitay-Goren, HB Patel, J Mintseris, J Waltenberger, JC Tille, JE Rundhaug, JH Qi, JH Qi, JR Jackson, JR Worley, K Maskos, KP Langton, KP Langton, LA Kelley, M Bandt De, M Benedetto Di, M Lohela, M Wisniewska, Michael D. Barker, Michael P. Seed, MS Brozzo, Munitta Muthana, N Manabe, Nicola J. Brown, Q Ebrahem, Rita Jones, S Rosengren, S Sivaprasad, SE Hoegy, V Chabottaux, WH Yu, WU Kim, Y Cao, Y Matsumoto, Yung-Yi Chen   +52 more
core   +1 more source

Serum vascular endothelial growth factor A and vascular endothelial growth factor receptor 2 as prognostic biomarkers for uterine cervical cancer [PDF]

International Journal of Clinical Oncology, 2019
There are few studies on serum vascular endothelial growth factors and receptors (VEGF/VEGFRs) in patients with uterine cervical cancer (CC). The aim of this study was to determine whether VEGF/VEGFRs could be used as prognostic biomarkers in patients with CC.A total of 107 patients with stage IB to IIB CC, who underwent radical hysterectomy at Tottori
Mayumi Sawada, Tetsuro Oishi, Hiroaki Komatsu, Shinya Sato, Jun Chikumi, Michiko Nonaka, Akiko Kudoh, Daiken Osaku, Tasuku Harada   +8 more
openaire   +2 more sources