Results 61 to 70 of about 13,622 (207)

Serum concentration of vascular endothelial growth factor and depth of trophoblastic invasion in ampullary ectopic pregnancy

Clinics
OBJECTIVE: To evaluate the association between the depth of trophoblastic infiltration and serum vascular endothelial growth factorconcentration in patients with an ampullary pregnancy. METHODS: This prospective cross-sectionalstudy involved 34 patients
Fábio Roberto Cabar, Décio Roberto Kamio Teshima, Pedro Paulo Pereira, Leila Antonangelo, Regina Schultz, Rossana Pulcineli Francisco   +5 more
doaj   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Measurement of plasma levels of vascular endothelial growth factor in prostate cancer patients: relationship with clinical stage, Gleason score, prostate volume, and serum prostate-specific antigen Medida da concentração plasmática do fator de crescimento do endotélio vascular em pacientes com câncer prostático: relação com estado clinico, gleason score, volume prostático e PSA sérico

Clinics, 2006
PURPOSE: This study focused on circulating levels of vascular endothelial growth factor in patients with prostate cancer compared to a normal population. METHODS: We analyzed 26 normal individuals and 80 patients with prostate cancer.
José Luis Ferreira Duque, Kevin R. Loughlin, Rosalyn M. Adam, Philip Kantoff, Eduardo Mazzucchi, Michael R. Freeman   +5 more
doaj   +1 more source

Dynamic Physicochemical Gradients for Tendon–Bone Regeneration

Advanced Functional Materials, EarlyView.
Dynamic physicochemical gradients offer a framework for reconnecting soft tendon and hard bone. This Review examines how hydration, transport, loading and degradation reshape these gradients during healing. Coordinating regional biological cues with progressive transfer of load from scaffold to tissue guides the design of interfaces that retain ...
Wanxue Wang, Minsheng Zhu, Junmiao Liu, Haowen Lu, Haoteng Wang, Yu Chen, Hua Liu, Zhengyu Xu, Zhiyong Sun, Huilin Yang, Yusen Qiao, Xia Zhao   +11 more
wiley   +1 more source

Evaluation of anticancer peptide VEGF111b secretion in HEK293 human cells

Fiyz̤, 2017
Background: VEGF111b is a new isoform of vascular endothelial growth factor (VEGF) recently considered as a new anticancer drug. The aim of this study was to evaluate the VEGF111b secretion from HEK293 cell wall in order to commercial production of this ...
Morteza Sadeghi , Zohreh Hojati
doaj  

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Self‐Healing Hydrogel‐Enabled Modular Assembly of Bilayered Skin Construct for Hair Follicle Regeneration

Advanced Healthcare Materials, EarlyView.
Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park, Su Yong Kim, MinSu Jeong, Beom Joon Kim, Shin Hyuk Kang, Won‐Gun Koh   +5 more
wiley   +1 more source

Atom‐Efficient Cerium‐Based Molecular Cages as Biocompatible Reactive Oxygen Scavengers

Advanced Healthcare Materials, EarlyView.
Discrete mixed‐valent cerium molecular cages organize accessible redox centers within confined coordination environments and scavenge superoxide, hydrogen peroxide, and hydroxyl radicals. Encapsulation of the lead cage in an ROS‐responsive DTP nanoplatform enables lesion‐associated delivery, attenuates macrophage oxidative stress and inflammation, and ...
Chao Li, Chunbai Xiang, Ye Xu, Yu Liu, Keze Hong, Fanchu Zeng, Gelin Xu, Zhao‐Xi Wang, Jonathan L. Sessler, Ping Gong   +9 more
wiley   +1 more source

CXC chemokine ligand 1 mediates adiponectin-induced angiogenesis in ovarian cancer

Tumor Biology, 2019
Objectives: Adiponectin is a cytokine secreted from adipose tissue that regulates energy homeostasis, inflammation, and cell proliferation. Obesity is associated with increased risk of various cancers, including ovarian cancer.
Yung-Taek Ouh, Hyun Woong Cho, Jae Kwan Lee, Song Hee Choi, Hyun Jin Choi, Jin Hwa Hong   +5 more
doaj   +1 more source

Vascular endothelium activation mechanisms study іn patients with psoriasis and essential hypertension

Zaporožskij Medicinskij Žurnal, 2016
The aim. To study Vascular Endothelial Growth Factor-A expression in patients with both psoriasis and hypertension. Methods and results. 102 patients were included. Vascular Endothelial Growth Factor-A level was detected with indirect ELISA method.
G. I. Makurina
doaj   +1 more source