Results 111 to 120 of about 28,223,317 (305)

Alternagin-C, a disintegrin-like protein from the venom of Bothrops alternatus, modulates a2ß1 integrin-mediated cell adhesion, migration and proliferation

Brazilian Journal of Medical and Biological Research, 2005
The alpha2ß1 integrin is a major collagen receptor that plays an essential role in the adhesion of normal and tumor cells to the extracellular matrix.
Selistre-de-Araujo H.S., Cominetti M.R., Terruggi C.H.B., Mariano-Oliveira A., De Freitas M.S., Crepin M., Figueiredo C.C., Morandi V.   +7 more
doaj  

Angiotensin converting enzyme and vascular endothelial growth factor responses to exercise training in claudicants: the role of ace inhibition [PDF]

, 2009
Exercise training is well recognised as an effective treatment for intermittent claudication. The mechanism underlying exercise induced improvements is multi-factorial but remains poorly understood.
Ng, P.
core  

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Expression of vascular endothelial growth factors A and C in human pancreatic cancer

World Journal of Gastroenterology, 2006
To study the expression of vascular endothelial growth factor A (VEGF-A) and VEGF-C and to determine whether the presence of VEGF-A and VEGF-C was associated with the clinicopathologic characteristics of pancreatic cancer.VEGF-A and VEGF-C mRNA transcripts were examined by Northern blot in 6 human pancreatic cancer cell lines and 8 normal pancreatic ...
Rui-Feng, Tang, Shu-Xia, Wang, Li, Peng, Shun-Xiang, Wang, Meng, Zhang, Zhi-Feng, Li, Zhi-Ming, Zhang, Yan, Xiao, Feng-Rui, Zhang   +8 more
openaire   +2 more sources

Angiogenesis-dependent and independent phases of intimal hyperplasia. [PDF]

, 2004
BACKGROUND: Neointimal vascular smooth muscle cell (VSMC) proliferation is a primary cause of occlusive vascular disease, including atherosclerosis, restenosis after percutaneous interventions, and bypass graft stenosis. Angiogenesis is implicated in the
De Muinck, E, Ferrara, N, Simons, M, Khurana, R, Zhuang, Z, Martin, JF, Murakami, M, Zachary, I, Bhardwaj, S, Yla-Herttuala, S   +9 more
core  

Spatially Controlled Embedded Bioprinting of Prevascularized Spheroids‐Containing Biopatch Enables Functional Skin Regeneration

Advanced Healthcare Materials, EarlyView.
A spatially controlled embedded bioprinting strategy enables precise engineering of prevascularized multicellular spheroids within skin‐derived dECM bioinks. Optimized spheroid size, composition, and spacing promote vascular maturation, paracrine signaling, and tissue integration, resulting in enhanced angiogenesis, blood perfusion, and functional skin
Minjun Ahn, Gyu Tae Park, Dongjun Lee, Sik Yoon, Sae‐Ock Oh, Jae Ho Kim, Byoung Soo Kim   +6 more
wiley   +1 more source

Vascular endothelial growth factor-C: its unrevealed role in fibrogenesis

American Journal of Physiology-Heart and Circulatory Physiology, 2014
Vascular endothelial growth factor (VEGF)-C is a key mediator of lymphangiogenesis. Our recent study shows that VEGF-C/VEGF receptors (VEGFR)-3 are significantly increased in the infarcted rat myocardium, where VEGFR-3 is expressed not only in lymph ducts but also in myofibroblasts, indicating that VEGF-C has an unrevealed role in fibrogenesis during ...
Tieqiang, Zhao, Wenyuan, Zhao, Weixin, Meng, Chang, Liu, Yuanjian, Chen, Yao, Sun   +5 more
openaire   +3 more sources

IFN-γ and TNF-α synergize to inhibit CTGF expression in human lung endothelial cells. [PDF]

, 2012
Connective tissue growth factor (CTGF/CCN2) is an angiogenetic and profibrotic factor, acting downstream of TGF-β, involved in both airway- and vascular remodeling.
Steffen Kunzmann, Roderich Laug, Laug, Roderich, Norbert Schütze, Krump-Konvalinkova, Vera, Boris W Kramer, Vera Krump-Konvalinkova, Kramer, Boris W., Markus Fehrholz, Schütze, Norbert, Kunzmann, Steffen, Schuetze, Norbert, Fehrholz, Markus, Speer, Christian P., Christian P Speer, Laug Roderich, Kunzmann Steffen, Krump-Konvalinkova Vera, Speer Christian P., Fehrholz Markus, Schütze Norbert, Kramer Boris W.   +21 more
core   +2 more sources

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Self‐Healing Hydrogel‐Enabled Modular Assembly of Bilayered Skin Construct for Hair Follicle Regeneration

Advanced Healthcare Materials, EarlyView.
Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park, Su Yong Kim, MinSu Jeong, Beom Joon Kim, Shin Hyuk Kang, Won‐Gun Koh   +5 more
wiley   +1 more source