Results 91 to 100 of about 28,223,317 (305)
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
The aim of the work was to assess vascular endothelial growth factor VEGF-C and vascular endothelial growth factor VEGF-D expression in ovarian carcinomas.Clinical records and preserved specimens from 80 patients with ovarian cacinoma who underwent treatment at Lower Silesia Centre of Oncology were examined consecutively.Most of analysed patients (n=53)
Barbara, Rossochacka-Rostalska +5 more
openaire +1 more source
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
Vascular endothelial growth factor-C in patients with breast cancer.
Metastatic spread of tumours is the major cause of death in patients with breast cancer. Despite the importance of the lymphatic system in tumour metastasis, little is known about the role of lymphangiogenesis in tumour growth and metastasis. This study was undertaken to evaluate the potential usefulness of plasma levels of lymphanagiogenesis factor ...
Al-Mowallad, Abdulfattah +7 more
openaire +3 more sources
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa +4 more
wiley +1 more source
Effect of inflammatory cytokines on the expression of the vascular endothelial growth factor‐C
The development of the vascular system involves vasculogenesis and angiogenesis. In vasculogenesis the endothelium of blood vessels forms by in situ differentiation from precursor cells called angioblasts. During later embryogenesis and adult life the new blood vessels are formed mainly via angiogenesis, most commonly involving sprouting of capillaries
K, Narko +3 more
openaire +3 more sources
Endothelial Wnt/β-catenin signaling inhibits glioma angiogenesis and normalizes tumor blood vessels by inducing PDGF-B expression [PDF]
Endothelial Wnt/β-catenin signaling is necessary for angiogenesis of the central nervous system and blood–brain barrier (BBB) differentiation, but its relevance for glioma vascularization is unknown. In this study, we show that doxycycline-dependent Wnt1
Devraj, Kavi +29 more
core +1 more source
Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu +7 more
wiley +1 more source
Greater Endothelial Apoptosis and Oxidative Stress in Patients with Peripheral Artery Disease
We compared apoptosis, cellular oxidative stress, and inflammation of cultured endothelial cells treated with sera from 156 subjects with peripheral artery disease (PAD) and 16 healthy control subjects.
Andrew W. Gardner +7 more
doaj +1 more source

