Results 11 to 20 of about 331,972 (306)

Upregulation of vascular endothelial growth factor receptor-1 contributes to sevoflurane preconditioning–mediated cardioprotection

Drug Design, Development and Therapy, 2018
Bin Qian,1 Yang Yang,2 Yusheng Yao,3 Yanling Liao,3 Ying Lin3 1Department of Anesthesiology, People’s Hospital Affiliated to Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China; 2Department of Anesthesiology, West China ...
Qian B, Yang Y, Yao Y, Liao Y, Lin Y
doaj   +1 more source

Vasoregulatory Autoantibodies and Clinical Outcome After Ischemic Stroke—PROSCIS‐B

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Vasoregulatory autoantibodies including autoantibodies targeting G‐protein–coupled receptors might play a functional role in vascular diseases.
Thomas G. Liman, Bob Siegerink, Sophie Piper, Rusan Catar, Guido Moll, Gabriela Riemekasten, Harald Heidecke, Peter U. Heuschmann, Mitchell S. V. Elkind, Duska Dragun, Matthias Endres   +10 more
doaj   +1 more source

Vascular Endothelial Growth Factor Receptor-1 Modulates Vascular Endothelial Growth Factor-Mediated Angiogenesis via Nitric Oxide [PDF]

The American Journal of Pathology, 2001
The known responses of vascular endothelial growth factor (VEGF) are mediated through VEGF receptor-2 (VEGFR-2/KDR) in endothelial cells. However, it is unknown whether VEGFR-1 (Flt-1) is an inert decoy or a signaling receptor for VEGF during physiological or pathological angiogenesis.
B, Bussolati, C, Dunk, M, Grohman, C D, Kontos, J, Mason, A, Ahmed   +5 more
openaire   +2 more sources

Encapsulated VEGF121-PLA microparticles promote angiogenesis in human endometrium stromal cells

Journal of Genetic Engineering and Biotechnology, 2021
Background In this study, Vascular Endothelial Growth Factor 121 expressed abundantly in endometrial stromal cells is encapsulated with poly-l-lactide and characterized the properties for endometrial angiogenesis.
Sunil Abraham, Geetha Sanjay, Noushin Abdul Majiyd, Amutha Chinnaiah   +3 more
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Adipose-Derived Stem Cells Improve Angiogenesis and Lymphangiogenesis in a Hypoxic Dermal Regeneration Model In Vitro

Medicina, 2023
Background and Objectives: Impaired wound healing represents an unsolved medical issue with a high impact on patients’ quality of life and global health care.
Benedikt Fuchs, Alexandra Birt, Nicholas Moellhoff, Constanze Kuhlmann, Riccardo E. Giunta, Paul Severin Wiggenhauser   +5 more
doaj   +1 more source

Vascular endothelial growth factor receptor‐1 in human cancer [PDF]

Cancer, 2010
AbstractThe human vascular endothelial growth factor receptor‐1 (VEGFR‐1, or Flt‐1) is widely expressed in normal and pathologic tissue and contributes to the pathogenesis of both neoplastic and inflammatory diseases. In human cancer, VEGFR‐1 mediated signaling is responsible for both direct tumor activation and angiogenesis.
Jonathan D, Schwartz, Eric K, Rowinsky, Hagop, Youssoufian, Bronislaw, Pytowski, Yan, Wu   +4 more
openaire   +2 more sources

Vascular endothelial growth factor receptor 1 in glioblastoma‑associated microglia/macrophages

Oncology Reports, 2020
The anti‑vascular endothelial growth factor‑A (VEGF‑A) monoclonal antibody (mAb) bevacizumab is an FDA‑approved monotherapy for the treatment of recurrent glioblastoma (GB), a highly angiogenic and infiltrative tumour. However, bevacizumab does not increase overall survival and blockade of VEGF‑A/VEGF receptor (VEGFR)‑2 signal transduction is ...
Lisi L., Ciotti G. M. P., Chiavari M., Ruffini F., Lacal P. M., Graziani G., Navarra P.   +6 more
openaire   +4 more sources

Flt-1 (Vascular Endothelial Growth Factor Receptor-1) Is Essential for the Vascular Endothelial Growth Factor–Notch Feedback Loop During Angiogenesis [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2013
Objective— Vascular endothelial growth factor (VEGF) signaling induces Notch signaling during angiogenesis. Flt-1/VEGF receptor-1 negatively modulates VEGF signaling. Therefore, we tested the hypothesis that disrupted Flt-1 regulation of VEGF signaling causes Notch pathway defects that contribute to dysmorphogenesis of Flt-1 ...
John C, Chappell, Kevin P, Mouillesseaux, Victoria L, Bautch   +2 more
openaire   +2 more sources

Vascular Endothelial Growth Factor Receptor-1 and Neuropilin-2 Form Complexes [PDF]

Journal of Biological Chemistry, 2001
The products of the neuropilin-1 (Np-1) and neuropilin-2 (Np-2) genes are receptors for factors belonging to the class 3 semaphorin family and participate in the guidance of growing axons to their targets. In the presence of heparin-like molecules, both receptors also function as receptors for the heparin-binding 165-amino acid isoform of vascular ...
Z, Gluzman-Poltorak, T, Cohen, M, Shibuya, G, Neufeld   +3 more
openaire   +2 more sources

Immunohistochemical Evaluation of Candidate Biomarkers for Fluorescence-Guided Surgery of Myxofibrosarcoma Using an Objective Scoring Method

Biomedicines, 2023
Introduction: Myxofibrosarcoma (MFS) is the most common soft-tissue sarcoma subtype in elderly patients. Local recurrence (LR) remains a major concern as the lack of intraoperative guidance and an infiltrative growth pattern with long, slender tails ...
Zeger Rijs, Esther Belt, Gijsbert M. Kalisvaart, Cornelis F. M. Sier, Peter J. K. Kuppen, Arjen H. G. Cleven, Alexander L. Vahrmeijer, Michiel A. J. van de Sande, Pieter B. A. A. van Driel   +8 more
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