Results 31 to 40 of about 37,380,162 (289)

VEGF vascularization pathway in human intervertebral disc does not change during the disc degeneration process

BMC Research Notes, 2018
Objective During degeneration of the intervertebral disc ingrowth of blood vessels and nerves into the disc are associated with back pain. Vascular endothelial growth factors promote vasculogenesis by binding to the membrane vascular endothelial growth ...
Simona Capossela, Alessandro Bertolo, Kapila Gunasekera, Tobias Pötzel, Martin Baur, Jivko V. Stoyanov   +5 more
doaj   +1 more source

The structural and functional characterization of the extracellular domain of vascular endothelial growth factor receptors : their role in receptor activation and use as therapeutic targets [PDF]

, 2012
: The vascular endothelial growth factor (VEGF) family plays key roles in the development of the blood and lymphatic vasculature. Five members, VEGF A, B, -C, -D, and PlGF can be found in the human body.
Stuttfeld, Edward
core   +1 more source

Moxibustion inhibits growth of tumor by down-regulating expression of FGFR1 and VEGFR2 in mice with sarcoma

针刺研究, 2021
Objective To observe the effect of moxibustion on the growth of tumor and expression of fibroblast growth factor receptor 1(FGFR1) and vascular endothelial cell growth factor receptor 2(VEGFR2) in mice with sarcoma, so as to explore its mechanisms ...
LI Li-jun, LUO Min-xiang, HE Li-jiao, ZHAO Chang-lin   +3 more
doaj   +2 more sources

Angiogenesis in Ocular and Extraocular Sebaceous Carcinoma

Acta Dermato-Venereologica, 2019
To shed more light on the pathogenesis of sebaceous carcinoma, we analysed the expression of proteins related to angiogenesis in 18 ocular and 22 extraocular sebaceous carcinomas using a broad panel of immunohistochemical markers.
Ferdinand Toberer, Holger A. Haenssle, Arno Rütten, Dmitry Kazakov, Liubov Kastnerova, Alexander Enk, Wolfgang Hartschuh, Ines Bertlich, Julia Hartmann, Martin Laimer, Wolfgang Weyers, Peter Helmbold, Heinz Kutzner   +12 more
doaj   +1 more source

Soluble Vascular Endothelial Growth Factor Receptor 1 in Human Breast Milk

Hormone Research in Paediatrics, 2011
<i>Background/Aims:</i> Vascular endothelial growth factor (VEGF) is a potent proangiogenic protein that activates VEGF receptor (VEGFR-1, VEGFR-2) tyrosine kinases expressed by vascular endothelial cells. A soluble truncated form of VEGFR-1 (sVEGFR-1) binds to VEGF as strongly as full-length VEGFR-1 and inhibits VEGF activity. sVEGFR-1 can
Ozgurtas, Taner, Aydin, Ibrahim, Turan, Ozden, Koc, Esin, Hirfanoglu, Ibrahim M., Acikel, Cengiz H., Akyol, Mesut, Serdar, Muhittin, Erbil, Kemal M.   +8 more
openaire   +5 more sources

Serum Vascular Endothelial Growth Factor/Soluble Vascular Endothelial Growth Factor Receptor 1 Ratio Is an Independent Prognostic Marker in Pancreatic Cancer [PDF]

Pancreas, 2008
Tumor angiogenesis is the consequence of an imbalance between positive and negative angiogenic regulatory factors. We sought to determine the role of pretreated serum angiogenic factors, including vascular endothelial growth factor (VEGF), placental growth factor (PlGF), and soluble vascular endothelial growth factor receptor 1 (sVEGFR-1), in ...
Chang, Yu-Ting, Chang, Ming-Chu, Wei, Shu-Chen, Tien, Yu-Wen, Hsu, Chiun, Liang, Po-Chin, Tsao, Po-Nien, Jan, I-Shiow, Wong, Jau-Min   +8 more
openaire   +3 more sources

VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia [PDF]

, 2003
Vascular endothelial growth factor (VEGF-A) is a major regulator of blood vessel formation and function. it controls several processes in endothelial cells, such as proliferation, survival, and migration, but it is not known how these are coordinately ...
Shima, D., Christiana Ruhrberg, Betsholtz, C, Jeltsch, M, Abramsson, A., Shima, D, Matthew Golding, Lundkvist, A, Lundkvist, A., Golding, M, David Shima, Ruhrberg, C, Christopher Mitchell, Mitchell, C, Betsholtz, C., Kari Alitalo, Gerhardt, H, Ruhrberg, C., Christer Betsholtz, Golding, M., Jeltsch, M., Holger Gerhardt, Abramsson, A, Alitalo, K, Andrea Lundkvist, Fruttiger, M., Gerhardt, H., Alitalo, K., Alexandra Abramsson, Mitchell, C., Fruttiger, M, Michael Jeltsch, Marcus Fruttiger   +32 more
core   +1 more source

Endothelial Dysfunction in Breast Cancer In-Vivo Model

Proceedings, 2018
Although the endothelial dysfunction is related with tumor development, there is no consensus on the suppressive or supportive effect on tumor growth. The goal of the present study was to evaluate endothelial dysfunction related factors in animal breast ...
Buğra Elkar, Mustafa Barış, Meryem Çalışır, Yasemin Çakır, Safiye Aktaş, Merve Tütüncü, M. Kürşat Şimşek, Mustafa Seçil, Osman Yılmaz, Zekiye Altun   +9 more
doaj   +1 more source

Brain homeostasis : VEGF receptor 1 and 2 ; two unequal brothers in mind [PDF]

, 2013
Vascular endothelial growth factors (VEGFs), initially thought to act specifically on the vascular system, exert trophic effects on neural cells during development and adulthood.
Karl H. Plate, Plate, Karl, Wittko-Schneider, Ina M., Schneider, Fabian T., Fabian T. Schneider, Ina M. Wittko-Schneider   +5 more
core   +1 more source

Placental growth factor promotes atherosclerotic intimal thickening and macrophage accumulation [PDF]

, 2005
Background: Placental growth factor (PlGF) has been implicated in the pathophysiological angiogenesis and monocyte recruitment that underlie chronic inflammatory disease, but its role in atherosclerosis has not been examined.
Collen, Desire, Moons, L., Carmeliet, P, Zachary, IC, Khurana, R, Martin, JF, Zachary, I.C., Khurana, Rohit, Luttun, A, Martin, John F., Martin, J.F., Zachary, Ian C., Shafi, S, Shafi, S., Collen, D., Khurana, R., Shafi, Shahida, Luttun, A., Carmeliet, Peter, Luttun, Aernout, Moons, L, Moons, Lieve, Carmeliet, P.   +22 more
core   +1 more source