Patologìâ, 2019 Aim – to study VEGF-A, VEGFR-1, VEGFR-2 and CD34 immunohistochemical expression on the I, II, III, IV stages (pTNM) of colorectal adenocarcinoma development. Materials and methods.
M. A. Shyshkin
doaj +1 more source
Expression of lymphatic markers and lymphatic growth factors in psoriasis before and after anti-TNF treatment [PDF]
Anais Brasileiros de Dermatologia, 2014 BACKGROUND: Angiogenesis is an early stage of psoriatic lesion development, but less is known about lymphagiogenesis and its role in the development of psoriasis.
Aikaterini Evangelia Moustou +6 more
doaj +1 more source
Abl family kinases regulate endothelial barrier function in vitro and in mice. [PDF]
PLoS ONE, 2013 The maintenance of endothelial barrier function is essential for normal physiology, and increased vascular permeability is a feature of a wide variety of pathological conditions, leading to complications including edema and tissue damage.
Elizabeth M Chislock +1 more
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Current Approach to The Treatment of Infantile Hemangioma
Çocuk Dergisi, 2023 Infantile hemangioma (IH) is the most common benign vascular tumor of the infantile period. Although the etiopathology of IH is not well-known, two primary theories exist.
Aybüke Doğan +2 more
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Neuropilin-1/GIPC1 signaling regulates α5β1 integrin traffic and function in endothelial cells [PDF]
, 2009 Neuropilin 1 (Nrp1) is a coreceptor for vascular endothelial growth factor A165 (VEGF-A165, VEGF-A164 in mice) and semaphorin 3A (SEMA3A). Nevertheless, <i>Nrp1</i> null embryos display vascular defects that differ from those of mice lacking ...
Caccavari, Francesca +43 more
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Mechanisms of vascular morphogenesis and stabilization by VEGF dose [PDF]
, 2014 VEGF is the master regulator of angiogenesis and the most investigated factor in therapeutic angiogenesis approaches to induce the growth of new vessels that could restore oxygen and nutrients supply in tissues affected by ischemia.
Groppa, Elena
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
The effect of magnesium sulfate on gene expression in maternal microvascular endothelial cells
Hypertension in Pregnancy, 2018 Preeclampsia is a severe complication of pregnancy associated with maternal and fetal morbidity and mortality. To date, magnesium sulfate remains the preferred method of treatment used to reduce the development of eclampsia.
Dennis K. Lee +2 more
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Vascular Endothelial Growth Factor Receptor-2-Mediated Mitogenesis Is Negatively Regulated by Vascular Endothelial Growth Factor Receptor-1 in Tumor Epithelial Cells [PDF]
The American Journal of Pathology, 2001 Vascular endothelial growth factor (VEGF) receptors are present on nonendothelial cells suggesting that VEGF may mediate nonendothelial effects during organogenesis and tumorigenesis. Here we show that VEGF receptor-1 (VEGFR-1) negatively regulates VEGFR-2-mediated proliferation via nitric oxide (NO) in an epithelial cancer cell line ECV304.
C, Dunk, A, Ahmed
openaire +2 more sources
Kaposin-B enhances the PROX1 mRNA stability during lymphatic reprogramming of vascular endothelial cells by Kaposi's sarcoma herpes virus. [PDF]
, 2010 Kaposi's sarcoma (KS) is the most common cancer among HIV-positive patients. Histogenetic origin of KS has long been elusive due to a mixed expression of both blood and lymphatic endothelial markers in KS tumor cells.
Kafka, Darren +37 more
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