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Vascular Endothelial Growth Factor Receptor 2 [PDF]

open access: yesDefinitions, 2020
Introduction: Chronic myeloid leukemia (CML) is a myeloproliferative disorder derived by formation of Philadelphia chromosome (Ph chromosome). Formation of the Ph chromosome is caused by a reciprocal translocation between the chromosomes 9 and 22 t(9;22)(
Marwah H. Alagele   +2 more
semanticscholar   +2 more sources

Galectin-3 Enhances Vascular Endothelial Growth Factor-A Receptor 2 Activity in the Presence of Vascular Endothelial Growth Factor [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2021
Galectin-3 (Gal3) is a carbohydrate-binding protein reported to promote angiogenesis by influencing vascular endothelial growth factor-A receptor 2 (VEGFR2) signal transduction.
Issahy Cano   +14 more
doaj   +3 more sources

Monomeric gremlin is a novel vascular endothelial growth factor receptor-2 antagonist [PDF]

open access: yesOncotarget, 2016
Angiogenesis plays a key role in various physiological and pathological conditions, including inflammation and tumor growth. The bone morphogenetic protein (BMP) antagonist gremlin has been identified as a novel pro-angiogenic factor.
Ballmer-Hofer, Kurt   +10 more
core   +5 more sources

Grb10 Prevents Nedd4-mediated Vascular Endothelial Growth Factor Receptor-2 Degradation [PDF]

open access: hybridJournal of Biological Chemistry, 2004
One of the cellular mechanisms used to prevent continuous and enhanced activation in response to growth factors is the internalization and degradation of their receptors. Little is known about the molecular mechanisms involved in vascular endothelial growth factor receptor-2 (VEGF-R2) degradation.
Joseph Murdaca   +6 more
openalex   +5 more sources

A Naturally Occurring Soluble Form of Vascular Endothelial Growth Factor Receptor 2 Detected in Mouse and Human Plasma [PDF]

open access: bronzeMolecular Cancer Research, 2004
Angiogenesis and vasculogenesis are regulated in large part by several different growth factors and their associated receptor tyrosine kinases (RTKs). Foremost among these is the vascular endothelial growth factor (VEGF) family including VEGF receptor ...
John M.L. Ebos   +7 more
openalex   +2 more sources

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