Medicina, 2023 Background and Objectives: Impaired wound healing represents an unsolved medical issue with a high impact on patients’ quality of life and global health care.
Benedikt Fuchs +5 more
doaj +1 more source
Effects of diabetes on myocardial capillary density and serum angiogenesis biomarkers in male rats
Clinics, 2011 INTRODUCTION: Cardiovascular disease is one of the main causes of mortality and morbidity in diabetic patients. This study evaluated the effects of diabetes on myocardial capillary density and several serum angiogenic factors including nitric oxide ...
Majid Khazaei +5 more
doaj +1 more source
Diabetes & Vascular Disease Research, 2020 Peripheral artery disease is a severe complication of diabetes. We have reported that the deletion of angiotensin type 2 receptor in diabetic mice promoted vascular angiogenesis in the ischaemic muscle 4 weeks following ischaemia.
Stéphanie Robillard +6 more
doaj +1 more source
Structure-Activity Relationship of Indole-Tethered Pyrimidine Derivatives that Concurrently Inhibit Epidermal Growth Factor Receptor and Other Angiokinases. [PDF]
PLoS ONE, 2015 Antiangiogenic agents have been widely investigated in combination with standard chemotherapy or targeted cancer agents for better management of advanced cancers.
Jiho Song +7 more
doaj +1 more source
Serum vascular endothelial growth factor A and vascular endothelial growth factor receptor 2 as prognostic biomarkers for uterine cervical cancer [PDF]
International Journal of Clinical Oncology, 2019 There are few studies on serum vascular endothelial growth factors and receptors (VEGF/VEGFRs) in patients with uterine cervical cancer (CC). The aim of this study was to determine whether VEGF/VEGFRs could be used as prognostic biomarkers in patients with CC.A total of 107 patients with stage IB to IIB CC, who underwent radical hysterectomy at Tottori
Mayumi Sawada +8 more
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248 EXPRESSION AND LOCALIZATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR AND VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 IN EQUINE FOLLICLES [PDF]
Reproduction, Fertility and Development, 2004 Ovarian follicles undergo pronounced morphological changes, alternating between periods of growth and regression. The equine follicle will grow to an average of 45 mm in diameter at ovulation, and during the phase of growth, there is an increase in blood supply to the follicle. Vascular endothelial growth factor (VEGF) is a cytokine that interacts with
H.G. Pedersen +3 more
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Vascular endothelial growth factor C and vascular endothelial growth factor receptor 2 are related closely to the prognosis of patients with ovarian carcinoma [PDF]
Cancer, 2004 AbstractBACKGROUNDThe vascular endothelial growth factor (VEGF) family and VEGF receptors (VEGFR) play an essential role in the angiogenesis of both pathologic and nonpathologic conditions. However, the prognostic significance of VEGF and VEGFR expression in ovarian carcinoma is unclear.METHODSThe tissue expression levels of VEGF‐A, VEGF‐C, VEGFR‐2 ...
Naoyo, Nishida +5 more
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Glycocalyx regulation of vascular endothelial growth factor receptor 2 activity. [PDF]
FASEB J, 2019 ABSTRACT We have previously shown that knockdown of endomucin (EMCN), an integral membrane glycocalyx glycoprotein, prevents VEGF‐induced proliferation, migration, and tube formation in vitro and angiogenesis in vivo .
LeBlanc ME +6 more
europepmc +3 more sources
Potential autocrine function of vascular endothelial growth factor in head and neck cancer via vascular endothelial growth factor receptor-2 [PDF]
Modern Pathology, 2005 Vascular endothelial growth factor is a peptide with well-defined actions on the vasculature and fundamental role in tumor angiogenesis. Its action in vascular endothelium is exerted in a paracrine manner. The immunohistochemical expression of this protein by cancer cells in head and neck squamous cell carcinoma was correlated with increased tumor ...
Kyzas, P. A. +3 more
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Myoferlin Regulates Vascular Endothelial Growth Factor Receptor-2 Stability and Function [PDF]
Journal of Biological Chemistry, 2007 Myoferlin and dysferlin are members of the ferlin family of membrane proteins. Recent studies have shown that mutation or genetic disruption of myoferlin or dysferlin promotes muscular dystrophy-related phenotypes in mice, which are the result of impaired plasma membrane integrity. However, no biological functions have been ascribed to myoferlin in non-
Pascal N, Bernatchez +11 more
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