Results 51 to 60 of about 749,263 (385)
Serum vascular endothelial growth factor A and vascular endothelial growth factor receptor 2 as prognostic biomarkers for uterine cervical cancer [PDF]
International Journal of Clinical Oncology, 2019 There are few studies on serum vascular endothelial growth factors and receptors (VEGF/VEGFRs) in patients with uterine cervical cancer (CC). The aim of this study was to determine whether VEGF/VEGFRs could be used as prognostic biomarkers in patients with CC.A total of 107 patients with stage IB to IIB CC, who underwent radical hysterectomy at Tottori
Mayumi Sawada +8 more
openaire +2 more sources
The functions and applications of A7R in anti-angiogenic therapy, imaging and drug delivery systems
Asian Journal of Pharmaceutical Sciences, 2019 Vascular endothelial growth factor receptor 2 (VEGFR-2) and neuropilin-1 (NRP-1) are two prominent antiangiogenic targets. They are highly expressed on vascular endothelial cells and some tumor cells.
Lu Lu +4 more
doaj +1 more source
Hypoxia-induced reactive oxygen species cause chromosomal abnormalities in endothelial cells in the tumor microenvironment. [PDF]
PLoS ONE, 2013 There is much evidence that hypoxia in the tumor microenvironment enhances tumor progression. In an earlier study, we reported abnormal phenotypes of tumor-associated endothelial cells such as those resistant to chemotherapy and chromosomal instability ...
Miyako Kondoh +8 more
doaj +1 more source
Angiogenesis-dependent and independent phases of intimal hyperplasia. [PDF]
, 2004 BACKGROUND: Neointimal vascular smooth muscle cell (VSMC) proliferation is a primary cause of occlusive vascular disease, including atherosclerosis, restenosis after percutaneous interventions, and bypass graft stenosis. Angiogenesis is implicated in the
Bhardwaj, S +9 more
core +1 more source
VEGF: An essential mediator of both angiogenesis and endochondral ossification [PDF]
, 2007 During bone growth, development, and remodeling, angiogenesis as well as osteogenesis are closely associated processes, sharing some essential mediators.
Dai, J, Rabie, ABM
core +1 more source
Biomedicines, 2023 Introduction: Myxofibrosarcoma (MFS) is the most common soft-tissue sarcoma subtype in elderly patients. Local recurrence (LR) remains a major concern as the lack of intraoperative guidance and an infiltrative growth pattern with long, slender tails ...
Zeger Rijs +8 more
doaj +1 more source
International Journal of Molecular Medicine, 2004 It has been shown that vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor-2 (VEGFR-2) are upregulated in severe carotid stenosis. However, it is unknown whether carotid endarterectomy (CEA) affects serum level of these molecules.
Papalambros, E. +8 more
openaire +3 more sources
Direct sensing of endothelial oxidants by vascular endothelial growth factor receptor-2 and c-Src. [PDF]
PLoS ONE, 2011 BACKGROUND: ADPH oxidase-derived reactive oxygen species (ROS) play important roles in redox homeostasis and signal transduction in endothelial cells (ECs).
Monica Lee, Wing C Choy, Md Ruhul Abid
doaj +1 more source
Gynecology Obstetrics & Reproductive Medicine, 2022 OBJECTIVE: To examine early pregnancy levels of serum heme oxygenase-1, soluble vascular endothelial growth factor receptor-1, B-cell lymphoma/leukemia-2 in relation to unfavorable pregnancy outcomes, including preeclampsia, fetal growth restriction ...
Havva Sutcu +4 more
doaj +1 more source
Ubiquitin plays an atypical role in GPCR-induced p38 MAP kinase activation on endosomes. [PDF]
, 2015 Protease-activated receptor 1 (PAR1) is a G protein-coupled receptor (GPCR) for thrombin and promotes inflammatory responses through multiple pathways including p38 mitogen-activated protein kinase signaling.
Aguilar, Berenice +7 more
core +2 more sources