Results 131 to 140 of about 359,258 (362)

Data from Targeted Anti–Vascular Endothelial Growth Factor Receptor-2 Therapy Leads to Short-term and Long-term Impairment of Vascular Function and Increase in Tumor Hypoxia

, 2023
Marcela Franco, Shan Man, Limor Chen, Urban Emmenegger, Yuval Shaked, Alison Cheung, Allison S. Brown, Daniel J. Hicklin, F. Stuart Foster, Robert S. Kerbel   +9 more
openalex   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Inhibition of VEGF-Dependent Multistage Carcinogenesis by Soluble EphA Receptors

Neoplasia: An International Journal for Oncology Research, 2003
Elevated expression of Eph receptors has long been correlated with the growth of solid tumors. However, the functional role of this family of receptor tyrosine kinases in carcinogenesis and tumor angiogenesis has not been well characterized.
Nikki Cheng, Dana Brantley, Wei Bin Fang, Hua Liu, William Fanslow, Douglas Pat Cerretti, Katrin N. Bussell, Alastair D. Reith, Dowdy Jackson, Jin Chen   +9 more
doaj   +1 more source

Clinical outcomes of patients with metastatic renal cell carcinoma (mRCC) treated with vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitors (TKI) and mammalian target of rapamycin inhibitors (mTORI) after immuno-oncology (IO) checkpoint inhibitors [PDF]

, 2018
Jeffrey Graham, J. Connor Wells, R.R. McKay, Ulka N. Vaishampayan, Aaron R. Hansen, Frede Donskov, Georg A. Bjarnason, Benoit Beuselinck, Guillermo de Velasco, Mei Sheng Duh, Lynn Huynh, R. Chang, Giovanni Zanotti, Krishnan Ramaswamy, Toni K. Choueiri, D.Y.C. Heng   +15 more
openalex   +1 more source

3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research

Advanced Functional Materials, EarlyView.
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram, Majd Machour, Janette Zavin, Roy Meretzki, Reut Lev‐Ari, Shulamit Levenberg   +5 more
wiley   +1 more source

Clinical utility of ramucirumab in advanced gastric cancer

Biologics: Targets & Therapy, 2015
Matthew MK Chan,1,2 Katrin M Sjoquist,1,3 John R Zalcberg4 1NHMRC Clinical Trials Centre, University of Sydney, Sydney, NSW, Australia; 2Department of Medical Oncology, Central Coast Cancer Centre, Gosford Hospital, Gosford, NSW, Australia; 3Cancer Care ...
Chan MMK, Sjoquist KM, Zalcberg JR
doaj  

Gene Expression Analysis of VEGF and Its Receptors and Assessment of Its Serum Level in Unexplained Recurrent Spontaneous Abortion [PDF]

Cell Journal, 2015
Objective: Unexplained recurrent spontaneous abortion (URSA) is one of the main complications of pregnancy which is usually defined as three or more consecutive pregnancy losses before the 20th week of gestation without a known cause.
Elham Amirchaghmaghi, Abbas Rezaei, Ashraf Moini, Mohammad Ali Roghaei, Maryam Hafezi, Reza Aflatoonian   +5 more
doaj  

Gintonin facilitates brain delivery of donepezil, a therapeutic drug for Alzheimer disease, through lysophosphatidic acid 1/3 and vascular endothelial growth factor receptors. [PDF]

J Ginseng Res, 2021
Choi SH, Lee NE, Cho HJ, Lee RM, Rhim H, Kim HC, Han M, Lee EH, Park J, Nah SY.   +9 more
europepmc   +1 more source

Urokinase Receptor and Vascular Endothelial Growth Factor Are Synergistically Associated with the Liver Metastasis of Colorectal Cancer [PDF]

, 2001
Hiroyuki Konno, Jinro Abe, Takeshi Kaneko, Megumi Baba, Atsushi Shoji, Kenichi Sunayama, Kinji Kamiya, Tatsuo Tanaka, Shohachi Suzuki, Satoshi Nakamura, Tetsumei Urano   +10 more
openalex   +1 more source

A Self‐Curling Si3N4‐Biofunctionalized Nerve Wrap for Suture‐Free Peripheral Nerve Repair with Multimodal Regenerative Bioregulation

Advanced Functional Materials, EarlyView.
Si3N4‐enhanced bioactive nanostructured adhesive wrap enables rapid conduit formation in wet environments, simplifying surgical procedures. Incorporated Si3N4 undergoes controlled hydrolysis within nanofibers, multi‐directionally modulating the peripheral nerve repair microenvironment for effective suture‐free repair.
Pengchao Ma, Yihao Liu, Bowen Ren, Chun‐Yi Yang, Xiaobin Luo, Peilun Hu, Jia Yang, Zheng Cao, Keya Mao, Jianheng Liu, Xiumei Wang   +10 more
wiley   +1 more source