Results 11 to 20 of about 365,143 (361)

Progress of study on inflammatory factors regulating function of vascular endothelial cells from type 1 diabetes mellitus [PDF]

open access: yesJichu yixue yu linchuang, 2021
Inflammatory factors are widely involved not only in the physiopathological process of type 1 diabetes mellitus (T1DM), but also in the regulation of vascular endothelial dysfunction. A variety of inflammatory factors affect the insulin signaling pathway
LI Qian, LIU Chun-hua, WANG Chen-yi, TAN Jiao-jiao, MA Yu-ping, LYU Hai-hong
doaj  

Modeling the Cluster Size Distribution of Vascular Endothelial Growth Factor (VEGF) Receptors

open access: yesBioinformatics and Biology Insights, 2022
We previously developed a method of defining receptor clusters in the membrane based on mutual distance and applied it to a set of transmission microscopy images of vascular endothelial growth factor receptors. An optimal length parameter was identified,
Emine Güven   +3 more
doaj   +1 more source

Effects of diabetes on myocardial capillary density and serum angiogenesis biomarkers in male rats

open access: yesClinics, 2011
INTRODUCTION: Cardiovascular disease is one of the main causes of mortality and morbidity in diabetic patients. This study evaluated the effects of diabetes on myocardial capillary density and several serum angiogenic factors including nitric oxide ...
Majid Khazaei   +5 more
doaj   +1 more source

Progress in Research on the Role of FGF in the Formation and Treatment of Corneal Neovascularization

open access: yesFrontiers in Pharmacology, 2020
Corneal neovascularization (CNV) is a sight-threatening disease usually associated with inflammatory, infectious, degenerative, and traumatic disorders of the ocular surface.
Mengji Chen   +4 more
doaj   +1 more source

Vascular protection by angiotensin receptor antagonism involves differential VEGF expression in both hemispheres after experimental stroke. [PDF]

open access: yesPLoS ONE, 2011
We identified that the angiotensin receptor antagonist, candesartan, has profound neurovascular protective properties when administered after ischemic stroke and was associated with a proangiogenic state at least partly explained by vascular endothelial ...
Weihua Guan   +9 more
doaj   +1 more source

Extrahepatic Angiogenesis: A Potential Common Pathophysiological Basis of Multiple Organ Dysfunction in Rats with Cholestasis Cirrhosis

open access: yesFrontiers in Bioscience-Landmark, 2023
Background: In addition to intrahepatic angiogenesis, patients with cholestasis cirrhosis develop extrahepatic vasculature disorders and functional disturbances of multiple organ systems.
Dandan Wang   +14 more
doaj   +1 more source

A peptide derived from TIMP-3 inhibits multiple angiogenic growth factor receptors and tumour growth and inflammatory arthritis in mice [PDF]

open access: yes, 2013
The binding of vascular endothelial growth factor (VEGF) to VEGF receptor-2 (VEGFR-2) on the surface of vascular endothelial cells stimulates many steps in the angiogenic pathway.
A Janssen   +52 more
core   +1 more source

Efficacy and safety of nintedanib in patients with non-small cell lung cancer, and novel insights in radiation-induced lung toxicity

open access: yesFrontiers in Oncology, 2023
Nintedanib is a tyrosine kinase inhibitor of fibroblast growth factor-, vascular endothelial growth factor-, and platelet-derived growth factor receptors.
Shu Yan   +6 more
doaj   +1 more source

VEGF: An essential mediator of both angiogenesis and endochondral ossification [PDF]

open access: yes, 2007
During bone growth, development, and remodeling, angiogenesis as well as osteogenesis are closely associated processes, sharing some essential mediators.
Dai, J, Rabie, ABM
core   +1 more source

Aktuelle Entwicklungen und Perspektiven zielgerichteter Therapien [PDF]

open access: yes, 2010
Current Developments and Perspectives in Targeted Therapies Many different approaches for improving the prognosis of patients with advanced non-small-cell lung cancer (NSCLC) are currently being investigated.
Dickgreber, Nicolas   +6 more
core   +1 more source

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