Results 321 to 330 of about 359,258 (362)

The vascular endothelial growth factor family and its receptors

Hematology/Oncology Clinics of North America, 2004
This article focuses on describing the biology of vascular endothelial growth factor (VEGF) and its receptors as well as the regulation of their expression. A thorough understanding of the VEGF system is paramount in optimizing antiangiogenic therapies as a component of antineoplastic regimens.
Alexander A, Parikh, Lee M, Ellis
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Signaling via Vascular Endothelial Growth Factor Receptors

Experimental Cell Research, 1999
Angiogenesis, or development of blood vessels from preexisting vasculature, has important functions under both normal and pathophysiological conditions. Vascular endothelial growth factor receptors 1-3, also known as flt-1, KDR, and flt-4, are endothelial cell-specific receptor tyrosine kinases which serve as key mediators of the angiogenic responses ...
T V, Petrova, T, Makinen, K, Alitalo
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Expression of Vascular Endothelial Growth Factor C and Vascular Endothelial Growth Factor Receptor 3 in Corneal Lymphangiogenesis

Experimental Eye Research, 2001
Lymphangiogenesis has been reported in vascularized corneas. However, the molecular mechanisms of lymphangiogenesis in the cornea are still unclear. Since lymphatic vessels may contribute to a decreased success rate of keratoplasty in vascularized cornea by accelerating antigen recognition and graft rejection, elucidation of the mechanisms of corneal ...
T, Mimura, S, Amano, T, Usui, Y, Kaji, T, Oshika, Y, Ishii   +5 more
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Developmental expression of vascular endothelial growth factor receptor 3 and vascular endothelial growth factor C in forebrain

Neuroscience, 2015
Increased understanding of the neurovascular niche suggests that development of the central nervous system (CNS) and its vasculature is coordinated through shared regulatory factors. These include the vascular endothelial growth factor (VEGF) family, reported to promote neuroproliferation and neuroprotection in addition to angiogenesis via its ...
M C, Ward, A M, Cunningham
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Vascular endothelial growth factor and vascular endothelial growth factor receptor-2 expression in mdx mouse brain

Brain Research, 2002
Recent data have demonstrated that vascular endothelial growth factor (VEGF) is expressed by subsets of neurons, coincident with angiogenesis within its developing cerebral cortex. In this study, with the aim of elucidating the mechanisms of vascular involvement during brain impairment in Duchenne muscular distrophy (DMD), we have correlated the ...
NICO, Beatrice, CORSI, Patrizia, RIBATTI, Domenico, VACCA, Angelo, RONCALI L.   +4 more
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Vascular Endothelial Growth Factor and Type 2 Receptor for This Factor in Vascular Malformations

Bulletin of Experimental Biology and Medicine, 2011
Immunohistochemical study revealed higher level of VEGF expression in vascular malformations compared to that in normal vessels of the adjacent tissue. VEGF expression was slightly higher in the endothelium of arteriovenous angiodysplasias than in venous angiodysplasias.
K A, Pavlov, E S, Gershtein, E A, Dubova, A I, Shchegolev   +3 more
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Immunohistochemical Expression of Vascular Endothelial Growth Factor and Vascular Endothelial Growth Factor Receptor in Canine Cutaneous Fibrosarcomas

Journal of Comparative Pathology, 2009
The expression of five markers associated with tumour angiogenesis, proliferation and apoptosis was studied in 24 canine cutaneous fibrosarcomas. Tumours were assigned histological grades and were immunohistochemically evaluated for the expression of vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor-2 (VEGFR-2 ...
A N, Al-Dissi, D M, Haines, B, Singh, B A, Kidney   +3 more
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Signal transduction by vascular endothelial growth factor receptors

Biochemical Society Transactions, 2003
Vascular endothelial growth factor (VEGF)/vascular permeability factor is the prototype for a growing family of dimeric growth factors, which exert their effects on vascular and lymphatic endothelial cells, as well as on a wide range of other cell types.
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Increased Vascular Endothelial Growth Factor and Receptors

American Journal of Respiratory and Critical Care Medicine, 2006
Increased vascularity is a feature of airway remodeling in asthma with the potential to contribute to a number of functional abnormalities in this chronic disease. Although various growth factors have been implicated in modulating vascularity, the important contributors in vivo are still being elucidated.
Feltis, Bryce N., Wignarajah, Dharshini, Zheng, Ling, Ward, Chris, Reid, David, Harding, Richard, Walters, E. Haydn   +6 more
openaire   +3 more sources

Endothelial Cell Death and Decreased Expression of Vascular Endothelial Growth Factor and Vascular Endothelial Growth Factor Receptor 2 in Emphysema

American Journal of Respiratory and Critical Care Medicine, 2001
Emphysema due to cigarette smoking is characterized by a loss of alveolar structures. We hypothesize that the disappearance of alveoli involves apoptosis of septal endothelial cells and a decreased expression of lung vascular endothelial growth factor (VEGF) and its receptor 2 (VEGF R2).
Y, Kasahara, R M, Tuder, C D, Cool, D A, Lynch, S C, Flores, N F, Voelkel   +5 more
openaire   +2 more sources