Results 331 to 340 of about 359,258 (362)
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Critical Reviews in Oncology/Hematology, 2000
Angiogenesis, formation of new vessels from pre-existing ones, results from stimulation of endothelial cells, which line the vessel wall. These cells will leave their resting state and start to digest the basement membrane, proliferate, migrate and eventually differentiate to form a hollow tube. All these steps can be induced by growth factors and this
P, Gerwins +2 more
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Angiogenesis, formation of new vessels from pre-existing ones, results from stimulation of endothelial cells, which line the vessel wall. These cells will leave their resting state and start to digest the basement membrane, proliferate, migrate and eventually differentiate to form a hollow tube. All these steps can be induced by growth factors and this
P, Gerwins +2 more
openaire +2 more sources
Zhonghua nei ke za zhi, 2006
To investigate the expression of vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor 2 (VEGFR-2/KDR) in lung tissues of emphysema patients.The peripheral lung tissues were obtained from 35 patients undergoing pneumonectomy.
Yue-hong, Wang +3 more
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To investigate the expression of vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor 2 (VEGFR-2/KDR) in lung tissues of emphysema patients.The peripheral lung tissues were obtained from 35 patients undergoing pneumonectomy.
Yue-hong, Wang +3 more
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The Histochemical Journal, 2001
Vascular endothelial growth factor is an angiogenic factor in vivo and in vitro that plays a crucial role in the control of blood vessel development and in pathological angiogenesis. The vascularized extraembryonic membranes of the chick embryo include the area vasculosa and the chorioallantoic membrane. In this study, we investigated the expression of
NICO, Beatrice +4 more
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Vascular endothelial growth factor is an angiogenic factor in vivo and in vitro that plays a crucial role in the control of blood vessel development and in pathological angiogenesis. The vascularized extraembryonic membranes of the chick embryo include the area vasculosa and the chorioallantoic membrane. In this study, we investigated the expression of
NICO, Beatrice +4 more
openaire +2 more sources
Vascular Endothelial Growth Factor (VEGF) Receptors
1995Abstract Two tyrosine kinases have been recently identified as putative VEGF receptors (deVries et al. 1992; Terman et al. 1992a). The flt-1 (fms-like-tyrosine kinase; Shibuya et al. 1990) and KOR (kinase domain region; Terman et al. 1991) proteins have been shown to bind VEGF with high affinity.
J E Park, N Ferrara
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Recent Patents on Anti-Cancer Drug Discovery, 2007
New blood vessel formation (angiogenesis) is fundamental to the process of tumor growth, invasion, and metastatic dissemination. The vascular endothelial growth factor (VEGF) family of ligands and receptors are well established as key regulators of these processes.
Anand, Veeravagu +5 more
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New blood vessel formation (angiogenesis) is fundamental to the process of tumor growth, invasion, and metastatic dissemination. The vascular endothelial growth factor (VEGF) family of ligands and receptors are well established as key regulators of these processes.
Anand, Veeravagu +5 more
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Diabetes, 1995
Ischemic eye disease often results in ocular neovascularization, presumably due to the elaboration of growth factors. Diabetic retinopathy is a classic example in which dramatic retinal neovascularization arises after ischemic retinal damage. The characterization of vascular endothelial growth factor (VEGF) as an angiogenic molecule whose expression is
H, Thieme +4 more
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Ischemic eye disease often results in ocular neovascularization, presumably due to the elaboration of growth factors. Diabetic retinopathy is a classic example in which dramatic retinal neovascularization arises after ischemic retinal damage. The characterization of vascular endothelial growth factor (VEGF) as an angiogenic molecule whose expression is
H, Thieme +4 more
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Inhibitors of Vascular Endothelial Growth Factor Receptor
2017Angiogenesis-targeting agents, predominantly inhibitors of vascular endothelial growth factor and its receptors, have become a mainstay in oncology practice over the last decade. The approved drugs, which include two antibodies and seven small molecule inhibitors, represent strong validation for the field of anti-angiogenesis in the treatment of cancer.
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Vascular Endothelial Growth Factor Receptors in Vascular Development and Hematopoiesis
2001Abstract The development of the vascular and hematopoietic systems of the vertebrate embryo occurs during early ontogeny and requires a variety of control mechanisms: those that specify mesodermal cells to form the lineage constituents, and those that control their proliferation and their coalescence to form a primitive vascular network.
Kari Alitalo +3 more
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A receptor for vascular endothelial growth factor that stimulates endothelial apoptosis.
Cancer research, 2002Vascular endothelial growth factor (VEGF) is a dimeric angiogenic factor that is overexpressed by many tumors and stimulates tumor angiogenesis. VEGF initiates signaling by dimerizing the receptors VEGFR-1 and VEGFR-2. The Fas receptor stimulates apoptosis, and artificial dimerization of the Fas cytoplasmic domain has been shown to induce apoptosis. We
T P, Quinn +4 more
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Cancer treatment and survivorship statistics, 2022
Ca-A Cancer Journal for Clinicians, 2022Kimberly D Miller +2 more
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