Results 331 to 340 of about 365,143 (361)

Modulation of vascular endothelial growth factor receptors in melanocytes

Experimental Dermatology, 2005
Abstract:  Vascular endothelial growth factor (VEGF) is constitutively produced by keratinocytes, but has no known epidermal target cell. We now report that normal human melanocytes (Mc) maintained in serum‐free, hormone‐, and growth factor‐supplemented medium lacking phorbol ester and choleragen constitutively express VEGF receptor‐1 (VEGFR‐1), VEGFR ...
Ellen J, Kim, Hee-Young, Park, Mina, Yaar, Barbara A, Gilchrest   +3 more
openaire   +2 more sources

The vascular endothelial growth factor family and its receptors

Hematology/Oncology Clinics of North America, 2004
This article focuses on describing the biology of vascular endothelial growth factor (VEGF) and its receptors as well as the regulation of their expression. A thorough understanding of the VEGF system is paramount in optimizing antiangiogenic therapies as a component of antineoplastic regimens.
Alexander A, Parikh, Lee M, Ellis
openaire   +2 more sources

Vascular endothelial growth factor receptor 3 in hypoxia‐induced vascular development

The FASEB Journal, 2004
ABSTRACT Reduced tissue oxygen tension (hyp‐oxia) is appreciated as an efficient stimulus for neovas‐cularization. The effect of hypoxia on the very first stages of vascular development is, however, less well characterized.
Ingrid, Nilsson, Charlotte, Rolny, Yan, Wu, Bronislaw, Pytowski, Dan, Hicklin, Kari, Alitalo, Lena, Claesson-Welsh, Stefan, Wennström   +7 more
openaire   +2 more sources

[Expression of pulmonary vascular endothelial growth factor and vascular endothelial growth factor receptor in emphysema].

Zhonghua nei ke za zhi, 2006
To investigate the expression of vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor 2 (VEGFR-2/KDR) in lung tissues of emphysema patients.The peripheral lung tissues were obtained from 35 patients undergoing pneumonectomy.
Yue-hong, Wang, Chun-xue, Bai, Ling, Mao, Min, Zhang   +3 more
openaire   +1 more source

Inhibitors of Vascular Endothelial Growth Factor Receptor

2017
Angiogenesis-targeting agents, predominantly inhibitors of vascular endothelial growth factor and its receptors, have become a mainstay in oncology practice over the last decade. The approved drugs, which include two antibodies and seven small molecule inhibitors, represent strong validation for the field of anti-angiogenesis in the treatment of cancer.
openaire   +1 more source

Vascular-endothelial-growth-factor-receptor-antagonists

Reactions Weekly, 2022
openaire   +1 more source

Cancer treatment and survivorship statistics, 2022

Ca-A Cancer Journal for Clinicians, 2022
Kimberly D Miller, Leticia M Nogueira, Angela B Mariotto   +2 more
exaly  

Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Laura A Huppert, Hope S Rugo
exaly  

Current treatment and recent progress in gastric cancer

Ca-A Cancer Journal for Clinicians, 2021
Smita S Joshi, Brian D Badgwell
exaly  

Vascular endothelial growth factor, vascular endothelial growth factor receptor-3 and cyclooxygenase-2 expression in psoriasis.

Analytical and quantitative cytology and histology, 2008
To investigate expression patterns and relationship of vascular endothelial growth factor (VEGF), vascular endothelial receptor-3 (VEGF-R3) (FLT-4) and cyclooxygenase-2 (COX-2) in psoriasis.Forty-three patients were included in this study. The clinical severity of psoriasis was assessed using the psoriasis area and severity index (PASI).
Başak, Yalçin, Gaye Güler, Tezel, Nilüfer, Arda, Mustafa, Erman, Nuran, Alli   +4 more
openaire   +1 more source