Results 131 to 140 of about 357,387 (353)

A prospective evaluation of the role of Vascular Endothelial Growth Factor (VEGF) and the immune system in stage III/IV melanoma [PDF]

, 2015
Nicole M Agostino, Christine Saraceni, Hope Kincaid, Wenjing Shi, Wendy K. Nevala, Svetomir N. Markovic, Suresh Nair   +6 more
openalex   +1 more source

Visible Light Induced DLP‐Printed Oxygen‐Releasing TPMS Scaffolds Mitigate Early Hypoxia in Bone Defects

Advanced Healthcare Materials, EarlyView.
Visible light‐induced digital light processing 3D printed Primitive‐triply periodic minimal surface hydrogels embed CaO2–Si core–shell nanoparticles to deliver short‐term oxygen during the avascular window. The scaffolds maintain cytocompatibility, elevate osteopontin in vitro, and enhance calvarial defect repair in vivo without toxicity.
Anastasia B. Timoshenko, Ali Ghasemkhani, Chanul Kim, Domenic J. Cordova, Maria Astudillo Potes, Valeria Aceves, Indranath Mitra, Justin E. Bird, Ryan S. Gray, Stephanie K. Seidlits, Benjamin D. Elder, Maryam Tilton   +11 more
wiley   +1 more source

Vascular Endothelial Growth Factor (VEGF) Signaling in Tumour Vascularization: Potential and Challenges

Current Vascular Pharmacology, 2017
Angiogenesis is defined as the physiological process by which new blood vessels develop from pre-existing vessels; either by sprouting or intussusception. Inhibition of angiogenesis is one of the most encouraging strategies to manage the growth and metastasis of cancers.
Siveen, Kodappully Sivaraman, Prabhu, Kirti, Krishnankutty, Roopesh, Kuttikrishnan, Shilpa, Tsakou, Magdalini, Alali, Feras Q., Dermime, Said, Mohammad, Ramzi M., Uddin, Shahab   +8 more
openaire   +4 more sources

A Sacrificial 3D Printed Vessel‐on‐Chip Demonstrates a Versatile Approach to Model Granulation Tissue

Advanced Healthcare Materials, EarlyView.
A novel method that combines 3D printing and organ‐on‐chip technology enables the creation of hollow channels lined with endothelial cells through a fibroblast‐populated connective tissue matrix. The model supports stable metabolic culture conditions, angiogenic sprouting, and immune cell migration, thereby demonstrating an easy and versatile method to
Jonas Jäger, Phil Berger, Andrew I. Morrison, Hendrik Erfurth, Maria Thon, Eva‐Maria Dehne, Susan Gibbs, Jasper J. Koning   +7 more
wiley   +1 more source

Vascular endothelial growth factor (VEGF) induces rapid prourokinase (pro-uPA) activation on the surface of endothelial cells [PDF]

, 2003
Gerald W. Prager, Johannes M. Breuss, Stefan Steurer, Judit Mihaly, Bernd R. Binder   +4 more
openalex   +1 more source

Engineering Complexity: Advances in 3D Breast Cancer Models for Precision Oncology

Advanced Healthcare Materials, EarlyView.
In vitro breast cancer models that closely mimic the complex biological and cellular interactions within the tumor microenvironment hold strong promise for enhancing our understanding of tumor progression, immune system behavior, and resistance to therapies, which are essential for developing personalized cancer treatments. Abstract Engineered in vitro
Wonwoo Jeong, Sang Jin Lee
wiley   +1 more source

Microphysiological Systems of Lymphatics and Immune Organs

Advanced Healthcare Materials, EarlyView.
This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain, Ankur Singh, Andrés J. García   +2 more
wiley   +1 more source

The Difference of Endometrial Vascular Endothelial Growth Factor (VEGF) Expression between Polycystic Ovarian Syndrome (PCOS) and Normal Women [PDF]

, 2020
Ricky Bernadi Saputra, Uki Retno Budihastuti, Sri Sulistyowati, Eriana Melinawati, Supriyadi Hari Respati   +4 more
openalex   +1 more source

Progressive Insights into 3D Bioprinting for Corneal Tissue Restoration

Advanced Healthcare Materials, EarlyView.
This review explores the potential of 3D bioprinting to replicate the complex structure and function of the human cornea. It highlights key advances in bioink development, printing modalities, and in vivo performance, while addressing current challenges and emerging strategies. The review emphasizes bioprinting's promise to overcome donor shortages and
Ilayda Namli, Deepak Gupta, Yogendra Pratap Singh, Pallab Datta, Muhammad Rizwan, Mehmet Baykara, Ibrahim T. Ozbolat   +6 more
wiley   +1 more source

A mechanistic computational model of HGF-VEGF-mediated endothelial cell proliferation and vascular permeability

iScience
Summary: Hepatocyte growth factor (HGF) and vascular endothelial growth factor (VEGF) are important pro-angiogenic factors in angiogenesis-dependent diseases.
Rebeca Hannah de Melo Oliveira, Akash Patil, Brian H. Annex, Arvind P. Pathak, Aleksander S. Popel   +4 more
doaj   +1 more source