Results 311 to 320 of about 364,472 (353)
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Vascular Endothelial Growth Factor (VEGF) in Autoimmune Diseases
Journal of Clinical Immunology, 2007Vascular endothelial growth factor (VEGF) is a potent stimulating factor for angiogenesis and vascular permeability. There are eight isoforms with different and sometimes overlapping functions. The mechanisms of action are under investigation with emerging insights into overlapping pathways and cross-talk between other receptors such as the neuropilins,
Jozélio Freire, Carvalho +2 more
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Vascular endothelial growth factor (VEGF) and its receptors
The FASEB Journal, 1999ABSTRACT Vascular endothelial growth factor (VEGF) is a highly specific mitogen for vascular endothelial cells. Five VEGF isoforms are generated as a result of alternative splicing from a single VEGF gene. These isoforms differ in their molecular mass and in biological properties such as their ability to bind to ...
G, Neufeld +3 more
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Vascular Endothelial Growth Factor (VEGF)
1995Abstract VEGF purified from conditioned media of normal and neoplastic cells is a glycoprotein of -45000 kDa (Ferrara and Henzel 1989). It is inactivated by reducing agents but it is heat- and acid-stable. By alternative splicing of RNA, VEGF may exist in four different homodimeric isoforms (Leung et al. 1989; Houck et al.
N Ferrara, J E Park
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The biology of vascular endothelial growth factor-B (VEGF-B)
Pulmonary Pharmacology & Therapeutics, 2006The formation of new blood vessels (angiogenesis) is critical for both embryonic development and a variety of normal postnatal physiological processes. Various pathological processes, most notably tumour growth and chronic inflammation, are also known to be dependent on the new vessel formation.
Andrew D, Nash +3 more
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Vascular endothelial growth factors (VEGF): role in pathological processes
Vestnik oftal'mologii, 2016Russian and foreign literature sources on vascular endothelial growth factors (VEGF) from different parts of the human body, their prevalence and involvement in pathological processes were analyzed. A conclusion has been drawn that further research on different types of VEGF is needed.
Yu A, Borzilova +2 more
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Vascular Endothelial Growth Factor (VEGF) Inhibition - A Critical Review
Anti-Cancer Agents in Medicinal Chemistry, 2007Angiogenesis, or formation of new blood capillaries from preexisting vessels, plays both beneficial and damaging roles in the organism. It is a result of a complex balance of positive and negative regulators, and vascular endothelial growth factor (VEGF) is one of the most important pro-angiogenic factors involved in tumor angiogenesis.
Irina Sousa, Moreira +2 more
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Vascular Endothelial Growth Factor (VEGF)
2016One of the best-validated signalling pathways in angiogenesis is vascular endothelial growth factor (VEGF) and its receptors. VEGF family encompasses 7 VEGF glycoproteins members including, VEGF-A, VEGF-B, VEGF-C, VEGF-D, and VEGF-E and placental growth factors 1 and 2 (PLGF). Of these, the very well-characterized member is VEGF-A. Vascular endothelial
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On the detection of neutrophil-derived vascular endothelial growth factor (VEGF)
Journal of Immunological Methods, 1999In recent years, several investigators have addressed the question of whether mature polymorphonuclear neutrophils (PMN) are able to secrete cytokines. Their studies have brought forward new and exciting discoveries, by establishing that the release of inflammatory cytokines constitutes a novel and important aspect of the neutrophil biology, thereby ...
SCAPINI, Patrizia +2 more
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Le VEGF (vascular endothelial growth factor)
Sang thrombose vaisseaux, 2009Auteur(s) : Yasmine Zouggari Inserm 970, PARCC, 56 Rue Leblanc 75015, Paris Les vaisseaux sanguins assurent le transport d’oxygene et de nutriments vers l’ensemble des organes et des tissus. La formation de neo-vaisseaux (ou angiogenese) s’observe dans des conditions physiologiques, lors du developpement embryonnaire et de la croissance.
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Vascular Endothelial Growth Factor (VEGF) Receptors
1995Abstract Two tyrosine kinases have been recently identified as putative VEGF receptors (deVries et al. 1992; Terman et al. 1992a). The flt-1 (fms-like-tyrosine kinase; Shibuya et al. 1990) and KOR (kinase domain region; Terman et al. 1991) proteins have been shown to bind VEGF with high affinity.
J E Park, N Ferrara
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