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Expression of vascular endothelial growth factor (VEGF) and VEGF receptors in human neuroblastomas
Medical and Pediatric Oncology, 2000Vascular endothelial growth factor (VEGF) is a specific endothelial cell mitogen that stimulates angiogenesis and plays a crucial role in tumor growth. The aim of the present study was to evaluate the expression of VEGF and of its two high-affinity tyrosine kinase receptors (KDR and Flt-1) in neuroblastoma surgical samples and cell lines.The VEGF, KDR,
Jason Perret
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Vascular Endothelial Growth Factor (VEGF) Inhibition by Small Molecules
Journal of Chemotherapy, 2004Angiogenesis is essential for primary tumours to grow and metastasise, and is driven by the production of positive angiogenic factors. The Vascular Endothelial Growth Factor (VEGF) family is central to the process of angiogenesis and comprises 5 molecules designated A, B, C, D and E. VEGF is overexpressed in several solid malignancies.
S I, Ahmed, A L, Thomas, W P, Steward
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Vascular Endothelial Growth Factor (VEGF) in Astrocytic Gliomas – A Prognostic Factor?
Journal of Neuro-Oncology, 1999Survival in astrocytic gliomas is closely related to WHO tumor grade. Within one tumor grade, especially in grade II and III tumors, the clinical course is variable and can hardly be predicted by histological criteria. Neovascularization is a neuropathological hallmark in high grade gliomas and angiogenic factors may play an important role in malignant
R D, Oehring +6 more
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Vascular endothelial growth factor (VEGF) signaling in tumor progression
Critical Reviews in Oncology/Hematology, 2007Vascular endothelial cells are ordinarily quiescent in adult humans and divide less than once per decade. When tumors reach a size of about 0.2-2.0mm in diameter, they become hypoxic and limited in size in the absence of angiogenesis. There are about 30 endogenous pro-angiogenic factors and about 30 endogenous anti-angiogenic factors.
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Vascular Endothelial Growth Factor (VEGF)
2020Alexandra Erdmann, Erin S. Costanzo
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Vascular Endothelial Growth Factor (VegF) Signaling
RCSB Protein Data Bank, 2022openaire +1 more source
[Vascular endothelial growth factor (VEGF)].
Nihon rinsho. Japanese journal of clinical medicine, 2011Nobuko, Sakita-Kawaguchi +2 more
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Vascular Endothelial Growth Factor (VegF) and Angiogenesis
RCSB Protein Data Bank, 2022openaire +1 more source