Results 51 to 60 of about 363,573 (256)

VEGF Trap In Combination With Radiotherapy Improves Tumor Control In U87 Glioblastoma [PDF]

, 2016
Purpose To determine the effect of vascular endothelial growth factor VEGF Trap (Regeneron Pharmaceuticals, Tarrytown, NY), a humanized soluble vascular endothelial growth factor (VEGF) receptor protein, and radiation (RT) on tumor growth in U87 ...
Burd, PhD, Randy, Cardi, MS, Chris, Daskalakis, Constantine, Dicker, Adam, MD, PhD, Holash, PhD, Jocelyn, Thakur, Mathew L., Wachsberger, PhD, Phyllis, Yancopoulos, PhD, George D.   +7 more
core   +1 more source

Vascular Endothelial Growth Factor (VEGF), Mast Cells and Inflammation

International Journal of Immunopathology and Pharmacology, 2013
Vascular endothelial growth factor (VEGF) is one of the most important inducers of angiogenesis, therefore blocking angiogenesis has led to great promise in the treatment of various cancers and inflammatory diseases. VEGF, expressed in response to soluble mediators such as cytokines and growth factors, is important in the physiological development of ...
Shaik Dasthagirisaheb, Y. B, VARVARA, GIUSEPPE, MURMURA, Giovanna, Saggini, A, Potalivo, G, Caraffa, A, Antinolfi, P, TETE', Stefano, TRIPODI, Domenico, Conti, F, CIANCHETTI, Ettore, TONIATO, ELENA, Rosati, M, CONTI, Pio, SPERANZA, Lorenza, PANTALONE, ANDREA, SAGGINI, Raoul, Theoharides, T. C, Pandolfi, F.   +18 more
openaire   +2 more sources

Tpl2 is required for VEGF-A-stimulated signal transduction and endothelial cell function

Biology Open, 2019
New blood vessel sprouting (angiogenesis) and vascular physiology are fundamental features of metazoan species but we do not fully understand how signal transduction pathways regulate diverse vascular responses.
Gareth W. Fearnley, Izma Abdul-Zani, Antony M. Latham, Monica C. Hollstein, John E. Ladbury, Stephen B. Wheatcroft, Adam F. Odell, Sreenivasan Ponnambalam   +7 more
doaj   +1 more source

Efficacy of tumor-targeting Salmonella typhimurium A1-R in combination with anti-angiogenesis therapy on a pancreatic cancer patient-derived orthotopic xenograft (PDOX) and cell line mouse models. [PDF]

, 2014
The aim of the present study was to examine the efficacy of tumor-targeting Salmonella typhimurium A1-R treatment following anti-vascular endothelial growth factor (VEGF) therapy on VEGF-positive human pancreatic cancer.
Bouvet, Michael, Chishima, Takashi, Endo, Itaru, Hiroshima, Yukihiko, Hoffman, Robert M, Ichikawa, Yasushi, Maawy, Ali, Matsuyama, Ryusei, Miwa, Shinji, Momiyama, Masashi, Mori, Ryutaro, Murakami, Takashi, Sato, Sho, Tanaka, Kuniya, Yamamoto, Mako, Yano, Shuya, Zhang, Yong, Zhao, Ming   +17 more
core   +2 more sources

Two Birds, One Stone: Double Hits on Tumor Growth and Lymphangiogenesis by Targeting Vascular Endothelial Growth Factor Receptor 3

Cells, 2019
Vascular endothelial growth factor receptor 3 (VEGFR3) has been known for its involvement in tumor-associated lymphangiogenesis and lymphatic metastasis. The VEGFR3 signaling is stimulated by its main cognate ligand, vascular endothelial growth factor C (
Ming-Chuan Hsu, Mei-Ren Pan, Wen-Chun Hung   +2 more
doaj   +1 more source

Prognostic value of vascular endothelial growth factor tumor tissue content of colorectal cancer [PDF]

, 2005
A longitudinal study was designed to quantify tumor tissue content of vascular endothelial growth factor (VEGF) in patients with colorectal cancer (CRC) and to evaluate its prognostic value in respect to the relapse-free and overall ...
Buonomo, O, D'Alessandro, R, Del Monte, G, Ferroni, P, Graziano, P, Guadagni, F, Mariotti, S, Martini, F, Roselli, M, Spila, A   +9 more
core   +2 more sources

The effect of Lactobacillus plantarum hydrolysates promoting VEGF production on vascular growth and hair growth of C57BL/6 mice

Journal of Analytical Science and Technology, 2019
Purpose Angiogenesis is critical in various biological processes, such as blood vessel growth, fetal differentiation, wound healing, and organ regeneration.
Young Min Woo, Ok Ju Kim, Eun Sol Jo, Min Young Jo, Mee Young Ahn, Young-Ho Lee, Chun-ri Li, Sang-Hyeon Lee, Jae-Suk Choi, Jong Myung Ha, Andre Kim   +10 more
doaj   +1 more source

Cholinergic neural activity directs retinal layer-specific angiogenesis and blood retinal barrier formation. [PDF]

, 2019
Blood vessels in the central nervous system (CNS) develop unique features, but the contribution of CNS neurons to regulating those features is not fully understood. We report that inhibiting spontaneous cholinergic activity or reducing starburst amacrine
Angelopoulos, CM, Bartakova, AB, Daneman, R, Goldberg, JL, Murphy, A, Nudleman, E, Pulido, RS, Shah, SH, Weiner, GA   +8 more
core   +1 more source

Effects of EGFR Expression on Anti-tumor Efficacy of Vandetanib or Cediranib Combined with Radiotherapy (RT) in U87 Human Glioblastoma (GBM) Xenografts [PDF]

, 2010
Introduction: Vandetanib is a receptor tyrosine kinase inhibitor (RTKI) with activity against vascular endothelial growth factor receptor-2 (VEGFR-2) and epidermal growth factor receptor (EGFR).
Dicker, A. P., Lawrence, Y. R., Liu, Y., Wachsberger, P.   +3 more
core   +2 more sources

THE ROLE OF VEGF SINGLE NUCLEOTIDE POLYMORPHISMS IN THE DEVELOPMENT OF CARDIOVASCULAR DISEASES

Медицинская иммунология, 2019
Cardiovascular diseases (CVD) are the main cause of mortality in the population. The pathophysiological processes underlying the development of CVD are inflammation, endothelial dysfunction, oxidative stress, atherosclerosis, fibrosis, dyslipidemia and ...
Anife Sevrievna Gaffarova, Igor Anatolievich Yatskov, Vladimir Alekseevich Beloglazov, Elizaveta Sergeevna Ageyeva, Elena Mikhailovna Dolya   +4 more
doaj   +1 more source