Results 71 to 80 of about 363,573 (256)

Effect of recombinant human vascular endothelial growth factor on testis tissue xenotransplants from prepubertal boys: a three-case study [PDF]

, 2019
Research question Does recombinant human vascular endothelial growth factor (VEGF-165) improve the efficiency of human immature testis tissue (ITT) xenotransplantation?
Goossens, Ellen, Kadam, Prashant, Ntemou, Elissavet, Van Laere, Sven, Van Saen, Dorien, Vicini, Elena   +5 more
core   +1 more source

Promoting vascular stability through Src inhibition and Tie2 activation: A model-based analysis

iScience
Summary: Dysregulated angiogenesis signaling leads to pathological vascular growth and leakage, and is a hallmark of many diseases including cancer and ocular diseases.
Yu Zhang, Christopher D. Kontos, Brian H. Annex, Aleksander S. Popel   +3 more
doaj   +1 more source

Insights into the Mechanisms Involved in Protective Effects of VEGF-B in Dopaminergic Neurons

Parkinson's Disease, 2017
Vascular endothelial growth factor-B (VEGF-B), when initially discovered, was thought to be an angiogenic factor, due to its intimate sequence homology and receptor binding similarity to the prototype angiogenic factor, vascular endothelial growth factor-
Beatrice Caballero, Scott J. Sherman, Torsten Falk   +2 more
doaj   +1 more source

Islet vascularization is regulated by primary endothelial cilia via VEGF-A-dependent signaling

eLife, 2020
Islet vascularization is essential for intact islet function and glucose homeostasis. We have previously shown that primary cilia directly regulate insulin secretion.
Yan Xiong, M Julia Scerbo, Anett Seelig, Francesco Volta, Nils O'Brien, Andrea Dicker, Daniela Padula, Heiko Lickert, Jantje Mareike Gerdes, Per-Olof Berggren   +9 more
doaj   +1 more source

A Switch in the Dynamics of Intra-Platelet VEGF-A from Cancer to the Later Phase of Liver Regeneration after Partial Hepatectomy in Humans. [PDF]

PLoS ONE, 2016
Liver regeneration (LR) involves an early inductive phase characterized by the proliferation of hepatocytes, and a delayed angiogenic phase distinguished by the expansion of non-parenchymal compartment.
Bibek Aryal, Toshiaki Shimizu, Jun Kadono, Akira Furoi, Teruo Komokata, Maki Inoue, Shunichiro Ikeda, Yoshihiko Fukukura, Masatoshi Nakamura, Munekazu Yamakuchi, Teruto Hashiguchi, Yutaka Imoto   +11 more
doaj   +1 more source

VEGF(164)-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization [PDF]

, 2003
Hypoxia-induced VEGF governs both physiological retinal vascular development and pathological retinal neovascularization. In the current paper, the mechanisms of physiological and pathological neovascularization are compared and contrasted.
Adamis, AP, Amano, S, Ambati, J, D'Amore, PA, Gragoudas, ES, Hida, T, Ishida, S, Kaji, Y, Miller, JW, Ng, YS, Oguchi, Y, Ogura, Y, Shima, DT, Usui, T, Yamashiro, K   +14 more
core   +1 more source

Therapeutic effect of apatinib-loaded nanoparticles on diabetes-induced retinal vascular leakage

International Journal of Nanomedicine, 2016
Ji Hoon Jeong,1,* Hong Khanh Nguyen,2,* Jung Eun Lee,1 Wonhee Suh2 1School of Pharmacy, Sungkyunkwan University, Suwon, 2College of Pharmacy, Chung-Ang University, Seoul, Korea *These authors contributed equally to this work Abstract: Apatinib, a
Jeong JH, Nguyen HK, Lee JE, Suh W
doaj  

Malignant peritoneal mesothelioma. Is there a new treatment?

Rare Tumors, 2009
The authors report a novel, alternative approach to treat malignant peritoneal mesothelioma (MPeM) targeting, vascular endothelial growth factor (VEGF) using anti-VEGF (bevacizumab) chemotherapy combination.
Kakil Ibrahim Rasul, David J Kerr
doaj   +1 more source

Slit2N and Robo4 regulate lymphangiogenesis through the VEGF-C/VEGFR-3 pathway [PDF]

, 2014
Background: Signaling through vascular endothelial growth factor C (VEGF–C) and VEGF receptor 3 (VEGFR-3) plays a central role in lymphangiogenesis and the metastasis of several cancers via the lymphatics.
Groopman, Jerome E, Jiang, Shuxian, Kuzontkoski, Paula M, Li, Dean Y, Yu, Jinlong, Zhang, Xuefeng, Zhu, Weiquan   +6 more
core   +2 more sources

Establishment of an abnormal vascular patterning model in the mouse retina

Journal of Pharmacological Sciences, 2018
Abnormalities in retinal blood vessels and neuronal function persist in eyes undergoing retinopathy of prematurity. In this study, we examined morphological and functional changes in retinal blood vessels and neurons in mice that had undergone short-term
Akane Morita, Shohei Sawada, Asami Mori, Shiho Arima, Kenji Sakamoto, Tohru Nagamitsu, Tsutomu Nakahara   +6 more
doaj   +1 more source