Results 71 to 80 of about 357,387 (353)

FOXP3 Polymorphism and Upregulation of the CXCL12‐CXCR4‐SNAIL Axis with High Infiltration of M2TAM by STAT3/NFKB Pathways Influence the Survival of Cervical Cancer Patients

Advanced Biology, EarlyView.
This study highlights how cervical carcinoma progression is shaped by immune–tumor interactions within the TME. M2‐TAM infiltration, regulated through STAT3/NF‐κB and linked to CXCL12–CXCR4, promotes immune suppression, angiogenesis, and poor survival.
George A. Lira, Fábio M. de Azevedo, Ingrid G. S. Lins, Janaína C. O. Crispim, Giovanna A. Lira, Rômulo S. Cavalcante, Ricardo Cobucci, Carolina O. Mendes‐Aguiar, Rafaela Torres Dantas Da Silva, Vinícius E. da Silva, Ryan C. Q. Aquino, Raimundo F. Araújo Júnior   +11 more
wiley   +1 more source

Prognostic value of vascular endothelial growth factor tumor tissue content of colorectal cancer [PDF]

, 2005
A longitudinal study was designed to quantify tumor tissue content of vascular endothelial growth factor (VEGF) in patients with colorectal cancer (CRC) and to evaluate its prognostic value in respect to the relapse-free and overall ...
Buonomo, O, D'Alessandro, R, Del Monte, G, Ferroni, P, Graziano, P, Guadagni, F, Mariotti, S, Martini, F, Roselli, M, Spila, A   +9 more
core   +2 more sources

Optical Aptasensors for the Analysis of the Vascular Endothelial Growth Factor (VEGF)

Analytical Chemistry, 2012
The vascular endothelial growth factor, VEGF, is an important biomarker for different diseases and clinical disorders. We present a series of optical aptasensor-based sensing platforms for VEGF that include the following: (i) A FRET-based sensor that involves the VEGF-induced separation of aptamer-functionalized quantum dots blocked by a quencher ...
Freeman, Ronit, Girsh, Julia, Jou, Amily Fang-ju, Ho, Ja-an Annie, Hug, Thomas, Dernedde, Jens, Willner, Itamar   +6 more
openaire   +3 more sources

A Vascularized Microphysiological System Reproducing Endochondral Ossification in Vitro to Study Ewing Sarcoma Proliferation and Migration

Advanced Functional Materials, EarlyView.
A biofabricated 3D in vitro model recapitulating endochondral ossification (ECO) is described, mimicking the steps from condensation to chondrogenesis and hypertrophy, culminating with vascularization of the hypertrophic construct. As a model proof of concept application, Ewing Sarcoma cells are seeded in the model, showing modifications in their ...
Maria Vittoria Colombo, Chiara Arrigoni, Tobias Faehling, Antonietta Verrillo, Viviana Secci, Thomas G. P. Grünewald, Giuseppe Talò, Alexandra Kummer, Jorge Gonzalez, Vincenzo De Rosa, Christian Candrian, Andrea Barbero, Florencia Cidre‐Aranaz, Matteo Moretti   +13 more
wiley   +1 more source

Reassessing vascular endothelial growth factor (VEGF) in anti-angiogenic cancer therapy

Cancer Treatment and Research Communications, 2022
Vascularization is fundamental to the growth and spread of tumor cells to distant sites. As a consequence, angiogenesis, the sprouting of new blood vessels from existing ones, is a characteristic trait of cancer.
Tobiloba C. Elebiyo, Damilare Rotimi, Ikponmwosa O. Evbuomwan, Rotdelmwa Filibus Maimako, Matthew Iyobhebhe, Oluwafemi Adeleke Ojo, Olarewaju M. Oluba, Oluyomi S. Adeyemi   +7 more
doaj   +1 more source

Neuropilin-1 Controls Endothelial Homeostasis by Regulating Mitochondrial Function and Iron-Dependent Oxidative Stress. [PDF]

, 2018
The transmembrane protein neuropilin-1 (NRP1) promotes vascular endothelial growth factor (VEGF) and extracellular matrix signaling in endothelial cells (ECs).
Bosseboeuf, E, Chikh, A, De Winter, N, Dufton, N, Gestri, G, Issitt, T, Raimondi, C, Randi, AM, Senatore, V   +8 more
core   +3 more sources

Vascular Endothelial Growth Factor (VEGF), Mast Cells and Inflammation

International Journal of Immunopathology and Pharmacology, 2013
Vascular endothelial growth factor (VEGF) is one of the most important inducers of angiogenesis, therefore blocking angiogenesis has led to great promise in the treatment of various cancers and inflammatory diseases. VEGF, expressed in response to soluble mediators such as cytokines and growth factors, is important in the physiological development of ...
Shaik Dasthagirisaheb, Y. B, VARVARA, GIUSEPPE, MURMURA, Giovanna, Saggini, A, Potalivo, G, Caraffa, A, Antinolfi, P, TETE', Stefano, TRIPODI, Domenico, Conti, F, CIANCHETTI, Ettore, TONIATO, ELENA, Rosati, M, CONTI, Pio, SPERANZA, Lorenza, PANTALONE, ANDREA, SAGGINI, Raoul, Theoharides, T. C, Pandolfi, F.   +18 more
openaire   +2 more sources

Inhibitory mechanism of vascular endothelial growth factor (VEGF) by bucillamine [PDF]

British Journal of Pharmacology, 2002
Vascular endothelial growth factor (VEGF) plays an important role in the neovascularization of ischaemic retinal diseases such as proliferative diabetic retinopathy. We determined that bucillamine, an anti‐rheumatic drug, inhibits the VEGF production induced by hypoxia in bovine retinal microcapillary endothelial cells (BREC).
Shinji, Koyama, Hitoshi, Takagi, Atsushi, Otani, Hideyasu, Oh, Kazuo, Nishimura, Yoshihito, Honda   +5 more
openaire   +2 more sources

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Vascular endothelium activation mechanisms study іn patients with psoriasis and essential hypertension

Zaporožskij Medicinskij Žurnal, 2016
The aim. To study Vascular Endothelial Growth Factor-A expression in patients with both psoriasis and hypertension. Methods and results. 102 patients were included. Vascular Endothelial Growth Factor-A level was detected with indirect ELISA method.
G. I. Makurina
doaj   +1 more source