Results 81 to 90 of about 364,472 (353)

Ubiquitination of basal VEGFR2 regulates signal transduction and endothelial function

Biology Open, 2017
Cell surface receptors can undergo recycling or proteolysis but the cellular decision-making events that sort between these pathways remain poorly defined.
Gina A. Smith, Gareth W. Fearnley, Izma Abdul-Zani, Stephen B. Wheatcroft, Darren C. Tomlinson, Michael A. Harrison, Sreenivasan Ponnambalam   +6 more
doaj   +1 more source

Markers of Angiogenesis Associated with Surgical Attenuation of Congenital Portosystemic Shunts in Dogs [PDF]

, 2014
BACKGROUND: Dogs with congenital portosystemic shunts (CPSS) have hypoplasia of the intrahepatic portal veins. Surgical CPSS attenuation results in the development of the intrahepatic portal vasculature, the precise mechanism for which is unknown ...
Chiarelli, Clifford, Efimova, Ferrara, Fossey, Futami, Gentilini, Greene, Ishikawa, Karayiannakis, Kruitwagen, Kummeling, Kummeling, Lee, Malamitsi-Puchner, Millauer, Mochida, Nissen, Papetti, Peters, Ross, Sato, Shimizu, Stieger, Taniguchi, Tivers, Tivers, Tivers, Vandesompele, Yamane   +29 more
core   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Endocannabinoid receptor blockade increases vascular endothelial growth factor and inflammatory markers in obese women with polycystic ovary syndrome [PDF]

, 2016
© 2016 John Wiley & Sons Ltd Context: Animal studies suggest that cannabinoid receptor-1 (CB-1) blockade reduces inflammation and neovascularization by decreasing vascular endothelial growth factor (VEGF) levels associated with a reduction in ...
Atkin, Stephen L., Coady, Anne-Marie, Javed, Zeeshan, Kilpatrick, Eric S., Sathyapalan, Thozhukat   +4 more
core   +1 more source

Aqueous Two‐Phase Bioinks for Discrete Packing and Compartmentalization of 3D Bioprinted Cells

Advanced Healthcare Materials, EarlyView.
Aqueous two‐phase systems (ATPS) enable the formation of biomimetic interfaces crucial for tissue engineering. However, clinical translation remains limited by the challenge of precisely controlling cellular compartmentalization. Here, we developed ATPS biomaterial inks for 3D bioprinting allowing tuneable droplet formation via NaCl modulation.
Martina Marcotulli, Arianna Iacomino, Federico Serpe, Lucia Iafrate, Marco Bastioli, Giorgia Montalbano, Michele D'Orazio, Biagio Palmisano, Silvia Franco, Arianna Mencattini, Roberta Angelini, Eugenio Martinelli, Alessandro Corsi, Mara Riminucci, Giancarlo Ruocco, Chiara Scognamiglio, Andrea Barbetta, Gianluca Cidonio   +17 more
wiley   +1 more source

Promoting vascular stability through Src inhibition and Tie2 activation: A model-based analysis

iScience
Summary: Dysregulated angiogenesis signaling leads to pathological vascular growth and leakage, and is a hallmark of many diseases including cancer and ocular diseases.
Yu Zhang, Christopher D. Kontos, Brian H. Annex, Aleksander S. Popel   +3 more
doaj   +1 more source

Insights into the Mechanisms Involved in Protective Effects of VEGF-B in Dopaminergic Neurons

Parkinson's Disease, 2017
Vascular endothelial growth factor-B (VEGF-B), when initially discovered, was thought to be an angiogenic factor, due to its intimate sequence homology and receptor binding similarity to the prototype angiogenic factor, vascular endothelial growth factor-
Beatrice Caballero, Scott J. Sherman, Torsten Falk   +2 more
doaj   +1 more source

Islet vascularization is regulated by primary endothelial cilia via VEGF-A-dependent signaling

eLife, 2020
Islet vascularization is essential for intact islet function and glucose homeostasis. We have previously shown that primary cilia directly regulate insulin secretion.
Yan Xiong, M Julia Scerbo, Anett Seelig, Francesco Volta, Nils O'Brien, Andrea Dicker, Daniela Padula, Heiko Lickert, Jantje Mareike Gerdes, Per-Olof Berggren   +9 more
doaj   +1 more source

A Switch in the Dynamics of Intra-Platelet VEGF-A from Cancer to the Later Phase of Liver Regeneration after Partial Hepatectomy in Humans. [PDF]

PLoS ONE, 2016
Liver regeneration (LR) involves an early inductive phase characterized by the proliferation of hepatocytes, and a delayed angiogenic phase distinguished by the expansion of non-parenchymal compartment.
Bibek Aryal, Toshiaki Shimizu, Jun Kadono, Akira Furoi, Teruo Komokata, Maki Inoue, Shunichiro Ikeda, Yoshihiko Fukukura, Masatoshi Nakamura, Munekazu Yamakuchi, Teruto Hashiguchi, Yutaka Imoto   +11 more
doaj   +1 more source

Prognostic value of carcinoembryonic antigen and vascular endothelial growth factor tumor tissue content in colorectal cancer [PDF]

, 2006
This study was designed to assess the prognostic significance of the combined measurement of vascular endothelial growth factor (VEGF) and carcinoembryonic antigen (CEA) tissue content with respect to relapse-free and overall survival of patients with ...
Buonomo, O, Del Monte, G, Ferroni, P, Formica, V, Guadagni, F, Martini, F, Palmirotta, R, Portarena, I, Roselli, M, Spila, A   +9 more
core   +1 more source