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Comprehensive analysis of the oncogenic roles of vascular endothelial growth factors and their receptors in stomach adenocarcinoma [PDF]

open access: yesHeliyon, 2023
Background: Vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs) play complicated oncogenic roles in multiple tumors by initiating and promoting tumor angiogenesis and lymphangiogenesis.
Jianxin Li, Ting Han
doaj   +2 more sources

Differential Regulation of Vascular Endothelial Growth Factors by Promoter-targeted shRNAs [PDF]

open access: yesMolecular Therapy: Nucleic Acids, 2015
Vascular endothelial growth factors (VEGFs) and their receptors (VEGF-R) are central regulators of vasculogenesis, angiogenesis, and lymphangiogenesis.
Nihay Laham-Karam   +3 more
doaj   +2 more sources

Encapsulated VEGF121-PLA microparticles promote angiogenesis in human endometrium stromal cells

open access: yesJournal of Genetic Engineering and Biotechnology, 2021
Background In this study, Vascular Endothelial Growth Factor 121 expressed abundantly in endometrial stromal cells is encapsulated with poly-l-lactide and characterized the properties for endometrial angiogenesis.
Sunil Abraham   +3 more
doaj   +1 more source

Inflammation in diabetic retinopathy: possible roles in pathogenesis and potential implications for therapy

open access: yesNeural Regeneration Research, 2023
Diabetic retinopathy, characterized as a microangiopathy and neurodegenerative disease, is the leading cause of visual impairment in diabetic patients.
Lei Tang, Guo-Tong Xu, Jing-Fa Zhang
doaj   +1 more source

VEGF-A, HGF and bFGF are involved in IL-17A-mediated migration and capillary-like vessel formation of vascular endothelial cells [PDF]

open access: yesIranian Journal of Immunology, 2021
Background: Interleukin (IL)-17A possesses biological activities to promote vascular endothelial cell migration and microvessel development. Objective: To clarify which angiogenic factors are involved in IL-17A-modified angiogenesis-related functions of ...
Muneo Numasaki, Koyu Ito
doaj   +1 more source

Vascular Endothelial Growth Factor [PDF]

open access: yesArteriosclerosis, Thrombosis, and Vascular Biology, 1993
Vascular endothelial growth factor (VEGF, VEGF-A) is a major regulator of physiological and pathological angiogenesis. Several VEGF inhibitors have been approved by the FDA for the treatment of advanced cancer and neovascular age-related macular degeneration.
openaire   +4 more sources

Application of neurotrophic and proangiogenic factors as therapy after peripheral nervous system injury

open access: yesNeural Regeneration Research, 2022
The intrinsic ability of peripheral nerves to regenerate after injury is extremely limited, especially in case of severe injury. This often leads to poor motor function and permanent disability.
Kamilla Faritovna Idrisova   +11 more
doaj   +1 more source

Endothelial Dysfunction in Breast Cancer In-Vivo Model

open access: yesProceedings, 2018
Although the endothelial dysfunction is related with tumor development, there is no consensus on the suppressive or supportive effect on tumor growth. The goal of the present study was to evaluate endothelial dysfunction related factors in animal breast ...
Buğra Elkar   +9 more
doaj   +1 more source

Progress of study on inflammatory factors regulating function of vascular endothelial cells from type 1 diabetes mellitus [PDF]

open access: yesJichu yixue yu linchuang, 2021
Inflammatory factors are widely involved not only in the physiopathological process of type 1 diabetes mellitus (T1DM), but also in the regulation of vascular endothelial dysfunction. A variety of inflammatory factors affect the insulin signaling pathway
LI Qian, LIU Chun-hua, WANG Chen-yi, TAN Jiao-jiao, MA Yu-ping, LYU Hai-hong
doaj  

Vasoregulatory Autoantibodies and Clinical Outcome After Ischemic Stroke—PROSCIS‐B

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Vasoregulatory autoantibodies including autoantibodies targeting G‐protein–coupled receptors might play a functional role in vascular diseases.
Thomas G. Liman   +10 more
doaj   +1 more source

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