Results 101 to 110 of about 982,599 (398)

Review Article-Branch Retinal Vein Occlusion in the Light of Anti-angiogenic Therapy [PDF]

, 2013
Branch retinal vein occlusion (BRVO) is one of the most common causes of acquired retinal vascular abnormality in adults and a frequent cause of visual loss. This circulatory disorder leads to retinal ischemia, which then induces up regulation of various
Bakhshinova, Svetlana A., Shahsuvaryan, Marianne L.   +1 more
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Statins and the vasculopathy of systemic sclerosis: potential therapeutic agents? [PDF]

, 2006
It has been postulated that endothelial cell injury is the initiating event in the pathogenesis of systemic sclerosis, causing attraction, attachment, migration and infiltration of activated T-cells and subsequent production of cytokines and growth ...
Derk, Chris T., Jimenez, Sergio A.
core   +2 more sources

Vascular endothelial growth factor-tyrosine kinase inhibitors: Novel mechanisms, predictors of hypertension and management strategies

American Heart Journal Plus, 2022
Vascular endothelial growth factor inhibition has become a cornerstone of cancer therapy. Significant adverse effect is associated with these therapies, with hypertension among the most prevalent.
Javier A. Gomez
doaj  

Particle-based simulation of ellipse-shaped particle aggregation as a model for vascular network formation [PDF]

, 2015
Computational modelling is helpful for elucidating the cellular mechanisms driving biological morphogenesis. Previous simulation studies of blood vessel growth based on the Cellular Potts model (CPM) proposed that elongated, adhesive or mutually attractive endothelial cells suffice for the formation of blood vessel sprouts and vascular networks ...
arxiv   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Myc Regulates Embryonic Vascular Permeability and Remodeling [PDF]

, 2009
Previous work has shown that c-Myc is required for adequate vasculogenesis and angiogenesis. To further investigate the contribution of Myc to these processes, we conditionally expressed c-Myc in embryonic endothelial cells using a tetracycline-regulated
Deutsch, Urban, Fleischer, Frank, Kempe, Sybille, Kokai, Enikoe, Leithaeuser, Frank, Marinković, Dragan, Schmidt, Volker, Voss, Florian, Wirth, Thomas, Wolburg, Hartwig   +9 more
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Cardiotoxicity with vascular endothelial growth factor inhibitor therapy

npj Precision Oncology, 2018
Angiogenesis inhibitors targeting the vascular endothelial growth factor (VEGF) signaling pathway (VSP) have been important additions in the therapy of various cancers, especially renal cell carcinoma and colorectal cancer.
R. Touyz, J. Herrmann
semanticscholar   +1 more source

Interplay of integrins and selectins in metastasis

Molecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva, Ashot Nersisyan, Alexander Tonevitsky   +2 more
wiley   +1 more source

Inhibitory effect on expression of angiogenic factors by antiangiogenic agents in renal cell carcinoma [PDF]

Since it has been widely recognised that renal cell carcinoma is refractory to standard therapies such as chemotherapy and radiotherapy, a new modality of treatment is needed.
A Okura, A Takahashi, A Takahashi, AP Levy, AP Levy, BAJ Evans, CPN Dinney, CT Barillie, D Mukhopadhyay, DT Zava, E Ikeda, EP Sipos, F Blei, FC White, FC White, H Adlercreutz, IR Record, J Drevs, J Folkman, J Folkman, JC Tsai, JW Slaton, KJ Kim, KP Claffey, KP Claffey, LA Liota, MS Pepper, N Masumori, N Miyao, N Weidner, RJ Tamargo, RK Singh, S Gilbertson-Beadling, S Mäkelë, T Akiyama, T Fotsis, TS O'Brien, YA Sidky, YB Kim, ZM Shao   +39 more
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Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis. [PDF]

, 2005
Fibroblast growth factors (FGFs) are a family of heparin-binding growth factors. FGFs exert their pro-angiogenic activity by interacting with various endothelial cell surface receptors, including tyrosine kinase receptors, heparan-sulfate proteoglycans ...
Aigner, Arany, Asplin, Auguste, Baird, Baird, Barleon, Bastaki, Bergonzoni, Bikfalvi, Birkle, Blotnick, Bornstein, Bossard, Bottazzi, Breviario, Brown, Brustle, Cao, Cao, Carmeliet, Carmeliet, Carmeliet, Castellon, Chadderton, Chang, Chang, Chang, Chi, Collo, Coltrini, Colvin, Comerota, Compagni, Conforti, Connolly, Costa, Cozzolino, Cross, Czubayko, Daviet, Davis, De Marchis, Dell’Era, Dell’Era, Dell’Era, Deng, Dennis, Desbaillets, Dirix, Eliceiri, Ensoli, Eriksson, Ferrara, Ferrara, Florkiewicz, Folkman, Folkman, Folkman, Freedman, Fulgham, Gabler, Gajdusek, Gajdusek, Garlanda, Gerritsen, Giavazzi, Giavazzi, Gillis, Giordano, Gleich, Gloe, Gonzalez, Griffioen, Grines, Gross, Gualandris, Gualandris, Hanahan, Hanneken, Hanneken, Hartnett, Henke, Herbert, Hiraoka, Ho, Hollingsworth, Hori, Hoying, Hsia, Iozzo, Itoh, Jaakkola, Javerzat, Jih, Kage, Kanda, Kanda, Kandel, Kaneko, Kasahara, Kazemi, Kitayama, Kiuru-Kuhlefelt, Klein, Konerding, Konkle, Koochekpour, Kumar, Kumar, Kumar, Kurz, Kuwabara, Laham, Landgren, Latini, Lazarous, Leali, Lederman, Lee, Lee, Li, Li, Lindahl, Liotta, Lopez, Lozano, Maciag, Magnusson, Mantovani, Margosio, Mathew, Matsumoto, Mattila, McCarthy, McCrohan, Mignatti, Mignatti, Miller, Mongiat, Montesano, Montesano, Morbidelli, Moscatelli, Nachman, Nguyen, Nico, Nicosia, Nurcombe, Ozaki, Padro, Parsons-Wingerter, Partridge, Passaniti, Pellegrini, Pendurthi, Peoples, Pepper, Pepper, Pepper, Perollet, Placanica, Polnaszek, Poole, Poon, Post, Presta, Presta, Presta, Presta, Presta, Presta, Pugh, Quarto, Rak, Reuss, Ria, Ribatti, Ribatti, Ribatti, Ribatti, Ribatti, Ribatti, Rissanen, Rousseau, Ruegg, Rusnati, Rusnati, Rusnati, Rusnati, Rusnati, Rusnati, Russo, Sahni, Sahni, Sahni, Sahni, Salgado, Salmivirta, Salustri, Schnaper, Schnaper, Seghezzi, Sellke, Senn, Sepp, Shaw, Sheibani, Shing, Shono, Shono, Simons, Simons, Singh, Souttou, Stokes, Syed, Tabata, Takahashi, Takei, Talarico, Tanghetti, Taraboletti, Taraboletti, Tassi, Taverna, Terranova, Tiefenbacher, Tille, Tobe, Tomanek, Ueno, Underwood, Unger, Vacca, Vlodavsky, Walford, Wang, Wang, Weidner, Weinstein, Wempe, Xu, Xue, Yamaguchi, Yamayoshi, Yoon, Zhang, Zhang, Zhao, Zhou, Zhou, Ziche, Ziche   +253 more
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