Updates on Anticancer Therapy-Mediated Vascular Toxicity and New Horizons in Therapeutic Strategies
Frontiers in Cardiovascular Medicine, 2021 Vascular toxicity is a frequent adverse effect of current anticancer chemotherapies and often results from endothelial dysfunction. Vascular endothelial growth factor inhibitors (VEGFi), anthracyclines, plant alkaloids, alkylating agents, antimetabolites,
Po-Yen Hsu +4 more
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Comparison of Continuous and Periodic Exercise on Serum Nitric Oxide Level and Vascular Endothelial Growth Factor in Old Rats [PDF]
Medical Laboratory Journal, 2023 Background and objectives: Considering the importance of aging and the associated physiological changes, as well as the effects of exercise on angiogenesis and cardiac index, this study aimed to compare continuous and periodic exercise in form of high ...
Abdolhamid Zokaei +3 more
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Intravitreal Anti-Vascular Endothelial Growth Factor Therapies for Retinal Disorders
Pharmaceuticals, 2023 Vascular endothelial growth factors (VEGFs) are key mediator of retinal and choroidal neovascularization as well as retinal vascular leakage leading to macular edema.
Abraham Hang +4 more
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Breaking the VE-cadherin bonds [PDF]
FEBS Letters / FEBS-Letters; FEBS Microbiol Lett (2008) epub ahead
of print, 2008 Exchanges between the blood compartment and the surrounding tissues require a tight regulation by the endothelial barrier. Recent reports inferred that VE-cadherin, an endothelial specific cell-cell adhesion molecule, plays a pivotal role in the formation, maturation and remodeling of the vascular wall. Indeed, a growing number of permeability inducing
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THE ROLE OF DYSLIPIDEMIA IN THE PROGRESSION OF DIABETIC RETINOPATHY
Медицинский совет, 2017 Angiogenesis factors, growth factors (vascular endothelial growth factor (VEGF), angiopoietin-2, insulin-like growth factor, etc.) and cytokines play the leading role in the production by endothelial cells of new retinal blood vessels, increased vascular
A. G. Kuzmin +2 more
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Frontiers in Physiology, 2020 Vasculogenesis, angiogenesis and arteriogenesis represent three crucial mechanisms involved in the formation and maintenance of the vascular network in embryonal and post-natal life. It has long been known that endothelial Ca2+ signals are key players in
Sharon Negri +4 more
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The role of vascular endothelial growth factor in ossification [PDF]
International Journal of Oral Science, 2012 Osteogenesis and angiogenesis are two closely correlated processes during bone growth, development, remodelling and repair.Vascular endothelial growth factor (VEGF) is an essential mediator during the process of angiogenesis. Based on an extensive literature search, which was carried out using the PubMed database and the keywords of osteogenesis, VEGF,
Ying-Ying Tan +6 more
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The effect of endurance resistance exercise combined with Lcitrulline malate supplement on FGF, VEGF, and fatigue among young bodybuilders [PDF]
فصلنامه ابن سینا, 2019 Background: Citrulline malate is a non-essential alpha-amino acid supplement resulting from arginine oxidation and may cause changes in the immunity, cardiovascular, and angiogenic mechanisms. It also reduces the rating of fatigue perception. The purpose
farah nameni +1 more
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Protein Kinase C-related Kinase and ROCK Are Required for Thrombin-induced Endothelial Cell Permeability Downstream from G{alpha}12/13 and G{alpha}11/q [PDF]
The Journal of Biological Chemistry 283, 44 (2008) 29888-96, 2008 Increase in vascular permeability occurs under many physiological conditions and is central in diverse human pathologies. Thrombin is a pro-coagulant serine protease, which causes the local loss of endothelial barrier integrity thereby enabling the rapid extravasation of plasma proteins and the local formation of fibrin-containing clots.
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How relevant are vascular endothelial growth factor and intercellular adhesion molecule in the systemic capillary leak syndrome of psoriasis? [PDF]
Anais Brasileiros de Dermatologia, 2017 : Psoriasis is a chronic disease, characterized by erythematous scaly lesions, presented in eight different forms: plaques, guttate, pustular, erythrodermic, inverse, nail and scalp psoriasis, and psoriatic arthritis.
Aline Lopes Bressan +4 more
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