Results 51 to 60 of about 558,315 (219)

Vascular endothelial growth factor B, a novel growth factor for endothelial cells. [PDF]

Proceedings of the National Academy of Sciences, 1996
We have isolated and characterized a novel growth factor for endothelial cells, vascular endothelial growth factor B (VEGF-B), with structural similarities to vascular endothelial growth factor (VEGF) and placenta growth factor. VEGF-B was particularly abundant in heart and skeletal muscle and was coexpressed with VEGF in these and other tissues.
Vladimir Joukov, Birgitta Olofsson, R F Pettersson, Katri Pajusola, Ulf Eriksson, G. von Euler, Arto Orpana, Arja Kaipainen, Olli Saksela, Kari Alitalo   +9 more
openaire   +3 more sources

Factors Affecting Compliance to Anti-Vascular Endothelial Growth Factor Treatment of Diabetic Macular Edema in a Cohort of Jordanian Patients

Clinical Ophthalmology, 2020
Nakhleh E Abu-Yaghi,1 Alaa M Abed,1 Dana F Khlaifat,2 Mohammed B Nawaiseh,2 Laith O Emoush,2 Heba Z AlHajjaj,2 Ala M Abojaradeh,2 Mariana N Hattar,2 Sura K Abusaleem,2 Hashem M Sabbagh,1 Yazan A Abu Gharbieh,1 Sura A Quaqazeh2 1Department of Special ...
Abu-Yaghi NE, Abed AM, Khlaifat DF, Nawaiseh MB, Emoush LO, AlHajjaj HZ, Abojaradeh AM, Hattar MN, Abusaleem SK, Sabbagh HM, Abu Gharbieh YA, Quaqazeh SA   +11 more
doaj  

Angiogenic Factors produced by Hypoxic Cells are a leading driver of Anastomoses in Sprouting Angiogenesis---a computational study [PDF]

Scientific Reports volume 8, Article number: 8726 (2018), 2018
Angiogenesis - the growth of new blood vessels from a pre-existing vasculature - is key in both physiological processes and on several pathological scenarios such as cancer progression or diabetic retinopathy. For the new vascular networks to be functional, it is required that the growing sprouts merge either with an existing functional mature vessel ...
arxiv   +1 more source

THE ROLE OF GROWTH AND ENDOTHELIAL FACTORS IN HEMOSTATIC DISORDER IN CHILDREN WITH THE SYNDROM DELAYED FETAL

Медицинский вестник Юга России, 2013
Violation of the natural defense mechanisms of endothelial dysfunction and an imbalance can occur many neurohumoral factors. The imbalance of angiogenic and antiangiogenic growth factors, endothelial, platelet factor closely related to disorders of ...
S. B. Berezhanskaya, E. A. Lukyanova, A. S. Todorova, E. Y. Kaushanskaya   +3 more
doaj   +1 more source

Vascular Inflammatory Diseases and Endothelial Phenotypes

Cells, 2023
The physiological functions of endothelial cells control vascular tone, permeability, inflammation, and angiogenesis, which significantly help to maintain a healthy vascular system.
Jenita Immanuel, Sanguk Yun
doaj   +1 more source

Vascular endothelial growth factor-tyrosine kinase inhibitors: Novel mechanisms, predictors of hypertension and management strategies

American Heart Journal Plus, 2022
Vascular endothelial growth factor inhibition has become a cornerstone of cancer therapy. Significant adverse effect is associated with these therapies, with hypertension among the most prevalent.
Javier A. Gomez
doaj  

c-Myc is essential to prevent endothelial pro-inflammatory senescent phenotype. [PDF]

PLoS ONE, 2013
The proto-oncogene c-Myc is vital for vascular development and promotes tumor angiogenesis, but the mechanisms by which it controls blood vessel growth remain unclear. In the present work we investigated the effects of c-Myc knockdown in endothelial cell
Victoria Florea, Nithya Bhagavatula, Gordana Simovic, Francisco Y Macedo, Ricardo A Fock, Claudia O Rodrigues   +5 more
doaj   +1 more source

Pattern formation of vascular network in a mathematical model of angiogenesis [PDF]

arXiv, 2021
We discuss the characteristics of the patterns of the vascular networks in a mathematical model for angiogenesis. Based on recent in vitro experiments, this mathematical model assumes that the elongation and bifurcation of blood vessels during angiogenesis are determined by the density of endothelial cells at the tip of the vascular network, and ...
arxiv  

Particle-based simulation of ellipse-shaped particle aggregation as a model for vascular network formation [PDF]

, 2015
Computational modelling is helpful for elucidating the cellular mechanisms driving biological morphogenesis. Previous simulation studies of blood vessel growth based on the Cellular Potts model (CPM) proposed that elongated, adhesive or mutually attractive endothelial cells suffice for the formation of blood vessel sprouts and vascular networks ...
arxiv   +1 more source

Stochastic models of the binding kinetics of VEGF-A to VEGFR1 and VEGFR2 in endothelial cells [PDF]

arXiv, 2016
Vascular endothelial growth factor receptors (VEGFRs) are receptor tyrosine kinases (RTKs) that regulate proliferation, migration, angiogenesis and vascular permeability of endothelial cells. VEGFR1 and VEGFR2 bind vascular endothelial growth factors (VEGFs), inducing receptor dimerisation and activation, characterised by phosphorylation of tyrosine ...
arxiv