Results 61 to 70 of about 119,420 (306)

Increased Platelet Reactivity and Proinflammatory Profile Are Associated with Intima–Media Thickness and Arterial Stiffness in Prediabetes

, 2022
Alterations of glucose homeostasis are associated with subclinical vascular damage; however, the role of platelet reactivity in this process has not been fully investigated.
L’Episcopo, Giuseppe, Giuseppe Coppolino, Miano, Nicoletta, Francesca Urbano, Stefania Di Mauro, Salvatore Piro, Agnese Filippello, Scamporrino, Alessandra, Di Pino, Antonino, Scicali, Roberto, Giuseppe L’Episcopo, Purrello, Francesco, Urbano, Francesca, Maurizio Di Marco, Di Marco, Maurizio, Di Mauro, Stefania, Stefano Leggio, Roberto Scicali, Nicoletta Miano, Francesco Purrello, Coppolino, Giuseppe, Leggio, Stefano, Antonino Di Pino, Alessandra Scamporrino, Filippello, Agnese, Piro, Salvatore   +25 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Vascular smooth muscle contraction in hypertension [PDF]

, 2018
Hypertension is a major risk factor for many common chronic diseases, such as heart failure, myocardial infarction, stroke, vascular dementia, and chronic kidney disease.
Aikaterini Anagnostopoulou, Rheure Alves-Lopes, Rhian M Touyz, Livia L Camargo, Augusto C Montezano, Francisco J Rios, Anders Arner   +6 more
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Óxido nítrico e alterações na reatividade vascular: envolvimento de nitrosotióis [PDF]

, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2013.A produção excessiva de óxido nítrico (NO) durante a sepse está relacionada com a disfunção ...
Benedet, Patrícia de Oliveira
core  

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Effect of tamoxifen on the coronary vascular reactivity of spontaneously hypertensive female rats

Brazilian Journal of Medical and Biological Research, 2011
Tamoxifen has been associated with a reduction in the incidence of myocardial infarction. However, the effects of tamoxifen on coronary reactivity have not been fully elucidated.
M.V. Borgo, A.B. Lopes, S.A. Gouvêa, W.G. Romero, M.R. Moyses, N.S. Bissoli, G.R. Abreu   +6 more
doaj   +3 more sources

Association between NT-pro-BNP levels and endothelial dysfunction assessed by digital thermal monitoring in patients with coronary artery disease

Frontiers in Cardiovascular Medicine
ObjectiveEndothelial dysfunction is a key mechanism in the progression of coronary artery disease (CAD). N-terminal pro-B-type natriuretic peptide (NT-pro-BNP), a biomarker of myocardial wall stress, has been associated with vascular abnormalities beyond
Ji-Hung Wang, Ji-Hung Wang, Ji-Hung Wang, I-Min Su, I-Min Su, I-Min Su, Bang-Gee Hsu, Bang-Gee Hsu, Bang-Gee Hsu, Bang-Gee Hsu   +9 more
doaj   +1 more source

Pregnancy blunts pulmonary vascular reactivity in dogs

, 1980
Pregnancy decreases systemic vascular reactivity but comparatively little is known about the effects of pregnancy on the pulmonary circulation. Pulmonary vascular resistance (PVR) during acute hypoxia was lower (P < 0.01) in eight intact anesthetized
J. T. Reeves, L. G. Moore
core   +1 more source