Results 91 to 100 of about 708,976 (400)

Endothelial dysfunction and vascular disease [PDF]

, 2009
The endothelium can evoke relaxations (dilatations) of the underlying vascular smooth muscle, by releasing vasodilator substances. The best characterized endothelium-derived relaxing factor (EDRF) is nitric oxide (NO).
Abeywardena, Aikawa, Ajayi, Alexopoulos, Alp, Anselm, Ardigo, Arehart, Argacha, Asano, Aubin, Aubin, Auch-Schwelk, Auch-Schwelk, Auch-Schwelk, Auch-Schwelk, August, Bachschmid, Barton, Basu, Bauersachs, Bechara, Behrendt, Belhassen, Bellamy, Bellien, Benndorf, Blanco-Rivero, Boban, Bode-Böger, Borg-Capra, Bos, Boulanger, Boulanger, Bouvet, Brandes, Briet, Bucala, Budhiraja, Bulckaen, Busse, Busse, Buzzard, Böger, Böger, Böhm, Cai, Camacho, Celermajer, Cernadas, Challah, Chambers, Chan, Chan, Chan, Charpie, Chauhan, Chen, Cheng, Chou, Chu, Cohen, Cohen, Coimbra, Cooke, Cosentino, Cosentino, Cox, Csiszar, Csiszar, Csiszar, Dantas, Dantas, Das, Davidge, Davidge, Davies, Davis, De Mey, De Mey, De Mey, De Vriese, DeLano, Dell’Agli, Derkach, Dhein, Dickson, Dimmeler, Dudzinski, Duffy, Duncan, Engler, Eringa, Eto, Feron, Ferreiro, Fichtlscherer, Filipe, Filser, Fisher, Fisslthaler, Flammer, Flavahan, Flavahan, Fleming, Fleming, Focardi, Fournet-Bourguignon, Frank, Fresquet, Furchgott, Furchgott, Furchgott, Furuhashi, Furuhashi, Félétou, Félétou, Félétou, Félétou, Félétou, Förstermann, Gamboa, Ganz, Gao, Garcia-Cohen, Ge, Ge, Gertz, Gill, Gisclard, Gluais, Gluais, Gluais, Goel, Gollasch, Graier, Grassi, Grisk, Gryglewski, Guns, Guzik, Halcox, Hambrecht, Han, Hanratty, Hansson, Hashikabe, Hattori, Heeba, Heiss, Herrmann, Heymes, Hibbert, Hirao, Hodgson, Holowatz, Hongo, Hoo, Houston, Houston, Hristovska, Husain, Hutri-Kahonen, Iellamo, Ignarro, Ignarro, Ignarro, Ijzerman, Ikeda, Indik, Inkster, Inoue, Iqbal, Ito, Iwama, Iwatani, Jankowski, Kagota, Kaiser, Kajiya, Kanani, Karagiannis, Kato, Katusic, Katusic, Katusic, Katusic, Katusic, Katz, Kaul, Kauser, Kennedy, Keung, Kim, Kim, Kirkby, Klöß, Knight, Koga, Koga, Kojda, Kubo, Kung, Kuriyama, Kuvin, Kähönen, Lamping, Landmesser, Landmesser, Landmesser, Lang, Lang, Lauer, Lavi, Lee, Lee, Lefèvre, Leikert, Lembo, Lesniewski, Leung, Levine, Levy, Li, Li, Li, Li, Li, Lida, Lin, Liu, Lockette, Looft-Wilson, Lopez-Sepulveda, Lu, Ludmer, Luz, Lyons, Lüscher, Lüscher, Lüscher, Lüscher, Lüscher, Lüscher, Lüscher, Lüscher, Lüscher, Macarthur, Machha, Machha, Maejima, Malo, Mancini, Marletta, Matoba, Matsumoto, Mayhan, Mayhan, Meyer, Michaud, Michel, Michel, Michel, Miller, Miller, Miller, Miller, Ming, Mitchell, Miyagawa, Moat, Mombouli, Mombouli, Mombouli, Mombouli, Moncada, Monobe, Monsalve, Montalcini, Morikawa, Moritoki, Motley, Mundy, Nagata, Nakamura, Nassar, Naya, Nietlispach, Nigris, Nigris, Nigris, Norel, Numaguchi, Obrosova, Okano, Okon, Ospina, O’Rourke, Pacher, Palm, Palmer, Palmer, Palmer, Palmer, Pannirselvam, Paulis, Pearson, Pellegrini, Perticone, Pierce, Quijano, Radomski, Rakobowchuk, Rapoport, Romero, Ross, Rossi, Roves, Rubanyi, Rubanyi, Rubanyi, Rubanyi, Rubanyi, Ryoo, Ryoo, Saifeddine, Santhanam, Santos, Sarr, Sartorio, Sata, Sbarouni, Schini, Schini, Schini, Schini-Kerth, Schroeter, Schäfer, Scott, Sekikawa, Sena, Shepherd, Shi, Shi, Shi, Shi, Shi, Shimokawa, Shimokawa, Shimokawa, Shimokawa, Shimokawa, Shimokawa, Shimokawa, Shimokawa, Shimokawa, Shimokawa, Shimokawa, Shirahase, Silva, Skott, Smith, Soares de Moura, Sousa, Spier, Spooner, Steinberg, Stepp, Stocker, Stocker, Stockley, Stuehr, Stähli, Subramanian, Sun, Suvorava, Suwaidi, Taddei, Taddei, Taddei, Taddei, Taddei, Taddei, Taddei, Tan, Tang, Tang, Tang, Tang, Tang, Tang, Taubert, Tesfamariam, Tesfamariam, Tesfamariam, Tesfamariam, Tostes, Touyz, Touyz, Traupe, Traupe, Treasure, Trochu, Tschudi, Tschudi, Uhrenholt, Uhrenholt, Ungvari, Vallance, Vallejo, Van Guilder, Van Guilder, Vanhoutte, Vanhoutte, Vanhoutte, Vanhoutte, Vanhoutte, Vanhoutte, Vanhoutte, Vanhoutte, Vanhoutte, Vanhoutte, Vanhoutte, Vanhoutte, Vanhoutte, Vanhoutte, Vanhoutte, Voetsch, von Schacky, Wallerath, Wang, Wang, Wassmann, Watts, Widder, Wilson, Wong, Wong, Xiang, Xiong, Xu, Xu, Yan, Yanagisawa, Yanagisawa, Yang, Yang, Yasuro, Yin, Zampetaki, Zerrouk, Zhang, Zhao, Zhong, Zhou, Zhou, Zhu, Zou, Zou, Álvarez, Álvarez   +460 more
core   +1 more source

Modelling Atherosclerotic Plaque Cap Mechanics: Microcalcifications Reduce Mechanical Properties in Mesenchymal Stromal Cell‐Based Model

Advanced Biology, EarlyView.
This study develops a tissue‐engineered model of the atherosclerotic cap using human mesenchymal stromal cells (MSCs). After 2 weeks of culture to produce a collagenous matrix, a mineralizing medium induces microcalcifications over 4 weeks. These constructs, imaged with second harmonic generation microscopy, lead to reduced ultimate stress at rupture ...
Imke L. Jansen, Deniz Şahin, Frank J.H. Gijsen, Eric Farrell, Kim van der Heiden   +4 more
wiley   +1 more source

Research advances on the role of Runx2-related miRNAs in vascular calcification of chronic kidney disease

Linchuang shenzangbing zazhi, 2022
Vascular calcification （VC） is a major cause of cardiovascular mortality in patients with chronic kidney disease （CKD）. Current studies suggest that VC of CKD is not simply an ectopic deposition of calcium phosphate crystals in vascular wall.
Lu Yang-yang, Bai Ya-ling, Xu Jin-sheng
doaj  

Generation of vascular endothelial and smooth muscle cells from human pluripotent stem cells

Nature Cell Biology, 2015
The use of human pluripotent stem cells for in vitro disease modelling and clinical applications requires protocols that convert these cells into relevant adult cell types. Here, we report the rapid and efficient differentiation of human pluripotent stem
Christoph Patsch, Ludivine Challet-Meylan, E. Thoma, E. Urich, Tobias Heckel, J. O’Sullivan, Stephanie Grainger, Friedrich G. Kapp, Lin Sun, K. Christensen, Yulei Xia, Mary H. C. Florido, Wei He, W. Pan, M. Prummer, C. Warren, R. Jakob‐Roetne, U. Certa, R. Jagasia, P. Freskgård, Isaac Adatto, D. Kling, P. Huang, L. Zon, E. Chaikof, Robert E. Gerszten, M. Graf, R. Iacone, Chad A. Cowan   +28 more
semanticscholar   +1 more source

Resident phenotypically modulated vascular smooth muscle cells in healthy human arteries. [PDF]

, 2012
Vascular interstitial cells (VICs) are non-contractile cells with filopodia previously described in healthy blood vessels of rodents and their function remains unknown.
Greenwood, IA, Harhun, MI, Huggins, CL, Khong, TK, Moss, RF, Raje, D, Ratnasingham, K, Reddy, M, Szewczyk, K, Vasilikostas, G, Wan, A   +10 more
core   +1 more source

Microphysiological Glomerular Filtration Barriers: Current Insights, Innovations, and Future Applications

Advanced Biology, EarlyView.
The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran, Kieu Ngo, David Buob, Hanna Debiec, Pierre Ronco, Guillaume Perry   +5 more
wiley   +1 more source

Vasoconstrictor prostanoids [PDF]

, 2010
In cardiovascular diseases and during aging, endothelial dysfunction is due in part to the release of endothelium-derived contracting factors that counteract the vasodilator effect of the nitric oxide.
Félétou, M, Huang, Y, Vanhoutte, PM
core   +1 more source

Fibronectin matrix polymerization regulates smooth muscle cell phenotype through a Rac1 dependent mechanism. [PDF]

PLoS ONE, 2014
Smooth muscle cells are maintained in a differentiated state in the vessel wall, but can be modulated to a synthetic phenotype following injury. Smooth muscle phenotypic modulation is thought to play an important role in the pathology of vascular ...
Feng Shi, Xiaochun Long, Allison Hendershot, Joseph M Miano, Jane Sottile   +4 more
doaj   +1 more source

3D Bioprinting of Thick Adipose Tissues with Integrated Vascular Hierarchies

Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
An advanced 3D bioprinting technique is used here to create thick adipose tissues with a central, vessel and extensive branching. The construct is made using alginate, gelatin and collagen‐based bioinks. Flow through the complex vessel network is demonstrated as well as its successful integration with a femoral artery following implantation in a rat ...
Idit Goldfracht, Majd Machour, Inbal Michael, Maria Bulatova, Janette Zavin, Shulamit Levenberg   +5 more
wiley   +1 more source

Increased neointimal thickening in dystrophin-deficient mdx mice.

PLoS ONE, 2012
BackgroundThe dystrophin gene, which is mutated in Duchenne muscular dystrophy (DMD), encodes a large cytoskeletal protein present in muscle fibers. While dystrophin in skeletal muscle has been extensively studied, the function of dystrophin in vascular ...
Uwe Rauch, Annelie Shami, Feng Zhang, Virginie Carmignac, Madeleine Durbeej, Anna Hultgårdh-Nilsson   +5 more
doaj   +1 more source