Results 91 to 100 of about 769,970 (260)

Origin and differentiation of vascular smooth muscle cells

Journal of Physiology, 2015
Vascular smooth muscle cells (SMCs), a major structural component of the vessel wall, not only play a key role in maintaining vascular structure but also perform various functions.
Gang Wang, Laureen Jacquet, Eirini Karamariti, Qingbo Xu   +3 more
semanticscholar   +1 more source

Targeting AGGF1 (angiogenic factor with G patch and FHA domains 1) for Blocking Neointimal Formation After Vascular Injury

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundDespite recent improvements in angioplasty and placement of drug‐eluting stents in treatment of atherosclerosis, restenosis and in‐stent thrombosis impede treatment efficacy and cause numerous deaths. Research efforts are needed to identify new
Yufeng Yao, Zhenkun Hu, Jian Ye, Changqing Hu, Qixue Song, Xingwen Da, Yubin Yu, Hui Li, Chengqi Xu, Qiuyun Chen, Qing Kenneth Wang   +10 more
doaj   +1 more source

BRG1 expression is increased in thoracic aortic aneurysms and regulates proliferation and apoptosis of vascular smooth muscle cells through the long non-coding RNA HIF1A-AS1 in vitro.

European Journal of Cardio-Thoracic Surgery, 2015
OBJECTIVES Brahma-related gene 1 (BRG1) and long non-coding RNAs (lncRNAs) play important roles in cellular processes. However, little is known regarding their roles in thoracic aortic aneurysms.
Shu-wei Wang, Xi-wu Zhang, Yang Yuan, Meng-wei Tan, Le Zhang, Xiang Xue, Yan Yan, Lin Han, Zhiyun Xu   +8 more
semanticscholar   +1 more source

TGF-β type II receptor in rat renal vascular development: Localization to juxtaglomerular cells [PDF]

, 1998
TGF-γ type II receptor in rat renal vascular development: Localization to juxtaglomerular cells. To further define the role of transforming growth factor-beta (TGF-γ) receptors in renal vascular development, detailed immunohistochemical studies of TGF-γ ...
Ballermann, Barbara J., Liu, Ailian
core   +1 more source

Increased neointimal thickening in dystrophin-deficient mdx mice.

PLoS ONE, 2012
BackgroundThe dystrophin gene, which is mutated in Duchenne muscular dystrophy (DMD), encodes a large cytoskeletal protein present in muscle fibers. While dystrophin in skeletal muscle has been extensively studied, the function of dystrophin in vascular ...
Uwe Rauch, Annelie Shami, Feng Zhang, Virginie Carmignac, Madeleine Durbeej, Anna Hultgårdh-Nilsson   +5 more
doaj   +1 more source

Optimal mechanical operation in the vicinity of curved vasculature [PDF]

arXiv, 2018
It has been shown that geometrical, structural properties vary along the length of the aortic arch. There is a scarcity of studies focus on the variation in the vessel wall thickness of aortic arch. The central premise of this study is that considering the variation in the vessel wall thickness along the circumference of the aortic arch to be governed ...
arxiv  

Gasdermin D affects aortic vascular smooth muscle cell pyroptosis and Ang II-induced vascular remodeling

Heliyon, 2023
Vascular smooth muscle cells (VSMCs) are primarily responsible for vasoconstriction and the regulation of blood pressure1. Pyroptosis, a particular form of regulated cell death, is involved in multiple vascular injuries, including hypertensive vascular ...
Zimin Fang, Gaojun Wu, Jian Sheng, Bozhi Ye, Zhouqing Huang, Jianjiang Xu, Jianqin Zhang, Jibo Han, Bingjiang Han, Jiajun Xu   +9 more
doaj  

MicroRNA-34a Induces Vascular Smooth Muscle Cells Senescence by SIRT1 Downregulation and Promotes the Expression of Age-Associated Pro-inflammatory Secretory Factors.

The journals of gerontology. Series A, Biological sciences and medical sciences, 2015
Arterial aging is a major risk factor for the occurrence of cardiovascular diseases. The aged artery is characterized by endothelial dysfunction and vascular smooth muscle cells altered physiology together with low-grade chronic inflammation.
Ileana Badi, I. Burba, C. Ruggeri, F. Zeni, M. Bertolotti, A. Scopece, G. Pompilio, A. Raucci   +7 more
semanticscholar   +1 more source

Smooth Muscle Progenitor Cells: Friend or Foe in Vascular Disease? [PDF]

The origin of vascular smooth muscle cells that accumulate in the neointima in vascular diseases such as transplant arteriosclerosis, atherosclerosis and restenosis remains subject to much debate.
de Kleijn, Dominique, Fledderus, Joost O., Pasterkamp, Gerard, van Oostrom, Olivia, Verhaar, Marianne C.   +4 more
core   +2 more sources

The model of circular and longitudinal smooth muscle motions in the motility of intestinal segment [PDF]

arXiv, 2014
Coordination in circular and longitudinal muscle motions are of crucial importance in the motor function of gastrointestinal (GI) tract. Intestinal wall motions depend on myogenic-active properties of smooth muscles layers of intestinal wall, which is the ability to create active contractile forces in response to distension.
arxiv