Syndecan2 Controls Vascular Smooth Muscle Development And Cytoskeletal Dynamics [PDF]
Syndecan2 is a member of the Syndecan family of transmembrane proteoglycans, expressed broadly in mammals. Syndecan2, along with Syndecan4, is expressed in the vasculature of mouse and man. Global deletion of Syndecan2 in mice does not affect viability
Atri, Deepak
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Syndecan-1 regulates vascular smooth muscle cell phenotype.
ObjectiveWe examined the role of syndecan-1 in modulating the phenotype of vascular smooth muscle cells in the context of endogenous inflammatory factors and altered microenvironments that occur in disease or injury-induced vascular remodeling.Methods ...
Somali Chaterji+4 more
doaj +1 more source
Prediction of Muscle Activations for Reaching Movements using Deep Neural Networks [PDF]
The motor control problem involves determining the time-varying muscle activation trajectories required to accomplish a given movement. Muscle redundancy makes motor control a challenging task: there are many possible activation trajectories that accomplish the same movement.
arxiv
Calcium-accumulating properties of subcellular fractions of bovine vascular smooth muscle. [PDF]
George D. Ford, Michael Heß
openalex +1 more source
Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension. [PDF]
Concentric lung vascular wall thickening due to enhanced proliferation of pulmonary arterial smooth muscle cells is an important pathological cause for the elevated pulmonary vascular resistance reported in patients with pulmonary arterial hypertension ...
Ayon, Ramon J+18 more
core +1 more source
Intimal hyperplasia in blood vessels is primarily caused by the migration and proliferation of vascular smooth muscle cells. Excessive intimal thickening characterizes atherosclerosis as well as bypass graft and angioplasty failures.
Alison T. Stopeck M.D.+2 more
doaj +1 more source
A Two-Phase Model of Early Fibrous Cap Formation in Atherosclerosis [PDF]
Atherosclerotic plaque growth is characterised by chronic inflammation that promotes accumulation of cellular debris and extracellular fat in the inner artery wall. This material is highly thrombogenic, and plaque rupture can lead to the formation of blood clots that occlude major arteries and cause myocardial infarction or stroke. In advanced plaques,
arxiv
Imbalance of Endothelium-derived Relaxing and Contracting Factors: A New Concept in Hypertension? [PDF]
The endothelium has a strategical anatomical position between the circulating blood and vascular smooth muscle cells. It has recently been recognized that endothelial cells play an important regulatory role in the circulation.
Lüscher, T. F.
core
TOLMESOXIDE, A DRUG THAT LOWERS BLOOD PRESSURE BY A DIRECT RELAXANT EFFECT ON VASCULAR SMOOTH MUSCLE [PDF]
John C. Doxey
openalex +1 more source
HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype. [PDF]
Aortic calcification is an important independent predictor of future cardiovascular events. We performed a genome-wide association meta-analysis to determine SNPs associated with the extent of abdominal aortic calcification (n = 9,417) or descending ...
Bagchi, Aranya+49 more
core