Pathophysiological Role of Caveolae in Hypertension [PDF]
Caveolae, flask-shaped cholesterol-, and glycosphingolipid-rich membrane microdomains, contain caveolin 1, 2, 3 and several structural proteins, in particular Cavin 1-4, EHD2, pacsin2, and dynamin 2.
Daumke, Oliver +4 more
core +2 more sources
Vascular calcification (VC) is a major cause of cardiovascular mortality in patients with chronic kidney disease (CKD). Current studies suggest that VC of CKD is not simply an ectopic deposition of calcium phosphate crystals in vascular wall.
Lu Yang-yang, Bai Ya-ling, Xu Jin-sheng
doaj
Guidance Molecules in Vascular Smooth Muscle
Several highly conserved families of guidance molecules, including ephrins, Semaphorins, Netrins, and Slits, play conserved and distinct roles in tissue remodeling during tissue patterning and disease pathogenesis.
Alexandra Christine Finney +3 more
doaj +1 more source
Micro-RNA-1 is decreased by hypoxia and contributes to the development of pulmonary vascular remodeling via regulation of sphingosine kinase 1 [PDF]
Sphingosine kinase 1 (SphK1) upregulation is associated with pathologic pulmonary vascular remodeling in pulmonary arterial hypertension (PAH), but the mechanisms controlling its expression are undefined.
Chen, Jiwang +6 more
core +1 more source
Guggulsterone, an anti-inflammatory phytosterol, inhibits tissue factor and arterial thrombosis [PDF]
Background: The phytosterol guggulsterone is a potent anti-inflammatory mediator with less side effects than classic steroids. This study assesses the impact of guggulsterone on tissue factor (TF) expression and thrombus formation.
Akhmedov, Alexander +8 more
core
Permanently proliferating rat vascular smooth muscle cell with maintained expression of smooth muscle characteristics, including actin of the vascular smooth muscle type. [PDF]
Werner W. Franke +3 more
openalex +1 more source
Vascular smooth muscle cell apoptosis in atherosclerosis [PDF]
Cell death has long been recognized within the vessel wall, in particular, in disease states such as atherosclerosis. The use of the term ‘necrotic core’ for the central lipid core of advanced lesions emphasizes this. Indeed there is obvious cell fragmentation and cell debris in areas of plaques, particularly the lipid core (Mitchinson et al.
openaire +3 more sources
Role of androgens in vascular smooth muscle cell calcification [PDF]
University of Technology, Sydney. Faculty of Science.Calcification is a common feature of advanced atherosclerotic lesions and is a clinically significant predictor of cardiovascular events.
Tsatralis, T
core
Stimulation of vascular smooth muscle cell prostacyclin and prostaglandin E2 synthesis by plasma high and low density lipoproteins. [PDF]
Kenneth B. Pomerantz +3 more
openalex +1 more source
Isolation and characterization of single vascular smooth muscle cells from spontaneously hypertensive rats. [PDF]
Bradley J. Bolzon, D W Cheung
openalex +1 more source

