Results 231 to 240 of about 231,096 (267)
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Lysolecithin actions on vascular smooth muscle cells
Biochemical and Biophysical Research Communications, 1992Oxidation of low density lipoprotein increases its atherogenic potential. During oxidation there is an extensive conversion of lecithin to lysolecithin. In rat aortic smooth muscle cells, 2-25 micrograms/ml lysolecithin elevated cytosolic calcium concentration up to 560%.
R, Locher +4 more
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Sodium Cotransport in Vascular Smooth Muscle Cells
Journal of Vascular Research, 1991Vascular smooth muscle cells possess a number of Na cotransport systems. Three of these cotransport systems, Na/Ca exchange, Na/H exchange and Na-K-Cl cotransport, have been the subject of an increasing number of investigations to determine the respective roles of these transporters in vascular smooth muscle cell function.
M E, O'Donnell, N E, Owen
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Ligustilide inhibits vascular smooth muscle cells proliferation
European Journal of Pharmacology, 2006Proliferation and migration of vascular smooth muscle cells (VSMCs) are believed to develop atherosclerosis and venous bypass graft disease. Ligustilide is widely used to treat some pathological settings such as atherosclerosis and hypertension. The aim of this study was to examine the effect of ligustilide on VSMCs proliferation. The results show that
Qun, Lu, Tai-Qiu, Qiu, Hong, Yang
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Smooth Muscle Progenitor Cells in Vascular Disease
Trends in Cardiovascular Medicine, 2004Vascular smooth muscle cells have long been described as phenotypically diverse, with some populations possessing the potential for monoclonal expansion within the adult vessel wall. Recent experimental and human data suggest a potential role in atherosclerotic plaque, transplant arteriopathy, and angiogenesis biology for putative smooth muscle ...
Chunsheng, Liu +3 more
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Endothelin degradation by vascular smooth muscle cells
Regulatory Peptides, 1996The mechanism(s) of degradation of the potent vasoconstrictor endothelin-1 (ET-1) by rat vascular smooth muscle A-10 cells, which possess the ETA receptor subtype, was investigated by incubating [125I]ET-1 (0.1 nM) with cells for 0-4 h at 37 degrees C in the presence and absence of lysosomal enzyme inhibitors, NH4Cl and chloroquine, and a neutral ...
H, Bermek +4 more
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Dexamethasone Suppresses Vascular Smooth Muscle Cell Proliferation
Journal of Surgical Research, 1999Experimental studies in vivo have demonstrated that dexamethasone inhibits neointimal hyperplasia following arterial injury. The mechanisms of this inhibition have not been clearly defined. Our objective was to test the hypothesis that dexamethasone directly suppresses smooth muscle cell (SMC) proliferation by inhibiting cell cycle progression and the ...
T D, Reil +4 more
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Calcium Channels in Vascular Smooth Muscle Cells
Journal of Vascular Research, 1995Control of intracellular Ca2+ ([Ca2+]i) is critical to vascular smooth muscle function. Calcium channels are the major route by which Ca2+ enters the smooth muscle cell. This article reviews the types of calcium channel present in vascular smooth muscle cells and their physiological and biochemical regulation.
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PC12 Cells Stimulate Vascular Smooth Muscle Growth
Journal of Cardiovascular Pharmacology, 2001Sympathetic nerves stimulate vascular growth. The mechanisms underlying this stimulation have not been fully elucidated. PC12 cells and cultures of vascular smooth muscle were used to study sympathetic stimulation of vascular smooth muscle growth. Media conditioned by undifferentiated and differentiated PC12 cells stimulated the growth of vascular ...
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